NUMB and EPS15

  • Number of citations of the paper that reports this interaction (PMID 9303539)
  • 81
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro)

NUMB

EPS15

Gene Name numb homolog (Drosophila) epidermal growth factor receptor pathway substrate 15
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder (mood-incongruent) ( 23092984)
  • Coronary artery calcification ( 17903303)
Protein-Protein Interactions 24 interactors: AP2A1 AP2A2 APP DPYSL2 EGFR EPS15 ITCH ITGB2 ITGB3 ITGB5 L1CAM LNX1 LNX2 MDM2 NOTCH1 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCZ RPL3 SIAH1 42 interactors: AGFG1 AGFG2 AP2A1 AP2A2 CLINT1 CORO7 CRK DNM1 DNM2 EGFR ELF3 EPN1 EPN2 GRB2 HGS ITSN1 ITSN2 LAPTM5 MOB4 NAGPA NEDD4 NUMB NUMBL OPTN PARK2 REPS2 RNF11 SCAMP1 SNAP91 SPG20 STAM2 STAMBP STON2 SYNJ1 TFAP2A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H UBQLN1
Entrez ID 8650 2060
HPRD ID 04767 08968
Ensembl ID ENSG00000133961 ENSG00000085832
Uniprot IDs P49757 B1AUU8 B7Z240 H7BYP0 P42566
PDB IDs 1C07 1EH2 1F8H 1FF1 2IV9 2JXC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adapter  affinities  arise  asymmetric  bind  bond  contain  diverse  division  domain  gp  gppy  helical  hydrogen  ldnpay  library  lnx  modes  motif  nak  nmr  npxy  peptide  phosphotyrosine  ptb  reveals  sheet  turn  y 
6g4  adaptin  adaptins  ap  cerevisiae  clathrin  coimmunoprecipitated  delineated  end3  endocytosis  glutathione  homology  immunoprecipitates  immunoreactivity  kd  keeping  mammals  metabolically  mu2  nh2  nih3t3  pheromone  polypeptides  precipitated  saccharomyces  sets  sigma  transferase  ubiquitous 
Tagcloud (Difference) ?
adapter  affinities  arise  asymmetric  bind  bond  contain  diverse  division  domain  gp  gppy  helical  hydrogen  ldnpay  library  lnx  modes  motif  nak  nmr  npxy  peptide  phosphotyrosine  ptb  reveals  sheet  turn  y 
6g4  adaptin  adaptins  ap  cerevisiae  clathrin  coimmunoprecipitated  delineated  end3  endocytosis  glutathione  homology  immunoprecipitates  immunoreactivity  kd  keeping  mammals  metabolically  mu2  nh2  nih3t3  pheromone  polypeptides  precipitated  saccharomyces  sets  sigma  transferase  ubiquitous 
Tagcloud (Intersection) ?