NUMB and ITGB3

  • Number of citations of the paper that reports this interaction (PMID 12606711)
  • 66
  • Data Source:
  • HPRD (in vitro)

NUMB

ITGB3

Gene Name numb homolog (Drosophila) integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder (mood-incongruent) ( 23092984)
  • Coronary artery calcification ( 17903303)
Protein-Protein Interactions 24 interactors: AP2A1 AP2A2 APP DPYSL2 EGFR EPS15 ITCH ITGB2 ITGB3 ITGB5 L1CAM LNX1 LNX2 MDM2 NOTCH1 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCZ RPL3 SIAH1 40 interactors: AKT1 ANGPTL3 CAPN1 CD36 CIB1 COL1A2 DAB1 DAB2 DOK1 EPS8 FBLN2 FGA FGG FLNA FLNB FN1 ILK ITGA2B ITGA5 ITGAV ITGB3BP KDR NID1 NUMB P2RY2 PDGFRA PDGFRB PDPK1 PECAM1 PTK2 PTK2B PXN SHC1 SRC TGM2 THBS1 THY1 TLN1 TNS2 VTN
Entrez ID 8650 3690
HPRD ID 04767 01428
Ensembl ID ENSG00000133961 ENSG00000259207
Uniprot IDs P49757 P05106
PDB IDs 1JV2 1KUP 1KUZ 1L5G 1M1X 1M8O 1MIZ 1MK7 1MK9 1RN0 1S4X 1TYE 1U8C 2INI 2K9J 2KNC 2KV9 2L1C 2L91 2LJD 2LJE 2LJF 2Q6W 2RMZ 2RN0 2VC2 2VDK 2VDL 2VDM 2VDN 2VDO 2VDP 2VDQ 2VDR 3FCS 3FCU 3IJE 3NID 3NIF 3NIG 3T3M 3T3P 3ZDX 3ZDY 3ZDZ 3ZE0 3ZE1 3ZE2 4G1E 4G1M
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adapter  affinities  arise  asymmetric  bind  bond  contain  diverse  division  domain  gp  gppy  helical  hydrogen  ldnpay  library  lnx  modes  motif  nak  nmr  npxy  peptide  phosphotyrosine  ptb  reveals  sheet  turn  y 
a4  acp5  apb  b4  blt1  blt2  conclusionsin  crac  ctsk  cytochemical  erosion  hydrolase  introductionbone  leukotriene  leukotrienes  lipoxygenase  ltb4  manuscript  methodswe  mmp9  nfatc1  nucleated  osteoclast  osteoclasts  pbmcs  phospholipase  resorbing  resultsour  u73122 
Tagcloud (Difference) ?
adapter  affinities  arise  asymmetric  bind  bond  contain  diverse  division  domain  gp  gppy  helical  hydrogen  ldnpay  library  lnx  modes  motif  nak  nmr  npxy  peptide  phosphotyrosine  ptb  reveals  sheet  turn  y 
a4  acp5  apb  b4  blt1  blt2  conclusionsin  crac  ctsk  cytochemical  erosion  hydrolase  introductionbone  leukotriene  leukotrienes  lipoxygenase  ltb4  manuscript  methodswe  mmp9  nfatc1  nucleated  osteoclast  osteoclasts  pbmcs  phospholipase  resorbing  resultsour  u73122 
Tagcloud (Intersection) ?