EPS15 and CORO7

Number of citations of the paper that reports this interaction (PMID 24768539)
1

Data Source:
BioGRID (affinity chromatography technology, pull down)

		EPS15	CORO7
Gene Name		epidermal growth factor receptor pathway substrate 15	coronin 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Coated Pit Membrane AP-2 Adaptor Complex Early Endosome Membrane Intracellular Membrane-bounded Organelle Ciliary Membrane	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Actin Cytoskeleton Membrane Integral Component Of Membrane Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Polyubiquitin Binding Identical Protein Binding	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	Golgi To Endosome Transport Endocytosis Epidermal Growth Factor Receptor Signaling Pathway Cell Proliferation Protein Transport Vesicle Organization Endocytic Recycling Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Clathrin Coat Assembly	Golgi To Endosome Transport Protein Transport Actin Cytoskeleton Organization Actin Filament Polymerization
Pathways		Signaling by EGFR EGFR downregulation Signaling by EGFR in Cancer Signaling by Ligand-Responsive EGFR Variants in Cancer Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by EGFRvIII in Cancer
Drugs
Diseases
GWAS		IgE grass sensitization ( 22036096)
Protein-Protein Interactions		42 interactors: AGFG1 AGFG2 AP2A1 AP2A2 CLINT1 CORO7 CRK DNM1 DNM2 EGFR ELF3 EPN1 EPN2 GRB2 HGS ITSN1 ITSN2 LAPTM5 MOB4 NAGPA NEDD4 NUMB NUMBL OPTN PARK2 REPS2 RNF11 SCAMP1 SNAP91 SPG20 STAM2 STAMBP STON2 SYNJ1 TFAP2A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H UBQLN1	8 interactors: ACTB AP1M1 AP2M1 EPS15 KLHL20 SRC TOB1 ZRANB1
Entrez ID		2060	79585
HPRD ID		08968	07975
Ensembl ID		ENSG00000085832	ENSG00000262246
Uniprot IDs		B1AUU8 B7Z240 H7BYP0 P42566	B3KSY4 P57737
PDB IDs		1C07 1EH2 1F8H 1FF1 2IV9 2JXC
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Endocytosis Vesicle-mediated Transport Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Protein K48-linked Ubiquitination Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Signal Transduction Protein Polyubiquitination Negative Regulation Of Signaling Regulation Of Signal Transduction Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Signaling Cell Communication Transport Post-Golgi Vesicle-mediated Transport Cellular Localization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Neuron Development Neurotrophin TRK Receptor Signaling Pathway Neuron Projection Development Establishment Of Localization In Cell Neuron Projection Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Neurotrophin Signaling Pathway Intracellular Transport Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Neuron Differentiation Cell Surface Receptor Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Cellular Response To Growth Factor Stimulus Establishment Of Protein Localization Response To Growth Factor Regulation Of Intracellular Signal Transduction Ephrin Receptor Signaling Pathway Protein Modification By Small Protein Conjugation Cellular Response To Hypoxia Protein Monoubiquitination Protein Catabolic Process Cellular Response To Decreased Oxygen Levels Receptor Internalization Protein Targeting To Lysosome	Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Membrane Organization Ephrin Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Golgi To Endosome Transport Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Defense Response To Virus By Virus Protein Transport Endosomal Transport Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Establishment Of Protein Localization Cytoplasmic Transport Intracellular Transport Golgi Vesicle Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Transport Cell Surface Receptor Signaling Pathway Organelle Organization Protein Localization Establishment Of Localization In Cell Response To Stimulus Axon Guidance Negative Regulation Of Signal Transduction Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Defense Response To Virus Negative Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Protein K33-linked Ubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Signaling Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Adherens Junction Organization Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Locomotion Cellular Localization Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Immune System Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Axonogenesis Viral Process Negative Regulation Of MRNA 3'-end Processing Cellular Response To Progesterone Stimulus Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cellular Response To Stimulus Chemotaxis
Tagcloud ?		6g4 adaptin adaptins ap cerevisiae clathrin coimmunoprecipitated delineated end3 endocytosis glutathione homology immunoprecipitates immunoreactivity kd keeping mammals metabolically mu2 nh2 nih3t3 pheromone polypeptides precipitated saccharomyces sets sigma transferase ubiquitous
Tagcloud (Difference) ?		6g4 adaptin adaptins ap cerevisiae clathrin coimmunoprecipitated delineated end3 endocytosis glutathione homology immunoprecipitates immunoreactivity kd keeping mammals metabolically mu2 nh2 nih3t3 pheromone polypeptides precipitated saccharomyces sets sigma transferase ubiquitous
Tagcloud (Intersection) ?