EPS15 and SNAP91

Number of citations of the paper that reports this interaction (PMID 12807910)
18

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		EPS15	SNAP91
Gene Name		epidermal growth factor receptor pathway substrate 15	synaptosomal-associated protein, 91kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Coated Pit Membrane AP-2 Adaptor Complex Early Endosome Membrane Intracellular Membrane-bounded Organelle Ciliary Membrane	Plasma Membrane Coated Pit Clathrin-coated Vesicle
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Polyubiquitin Binding Identical Protein Binding	Protein Binding 1-phosphatidylinositol Binding Protein Kinase Binding Clathrin Binding
	Biological Process	Golgi To Endosome Transport Endocytosis Epidermal Growth Factor Receptor Signaling Pathway Cell Proliferation Protein Transport Vesicle Organization Endocytic Recycling Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Clathrin Coat Assembly	Synaptic Transmission Protein Transport Clathrin Coat Assembly Regulation Of Clathrin-mediated Endocytosis
Pathways		Signaling by EGFR EGFR downregulation Signaling by EGFR in Cancer Signaling by Ligand-Responsive EGFR Variants in Cancer Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by EGFRvIII in Cancer
Drugs
Diseases
GWAS		IgE grass sensitization ( 22036096)	Bipolar disorder (mood-incongruent) ( 23092984)
Protein-Protein Interactions		42 interactors: AGFG1 AGFG2 AP2A1 AP2A2 CLINT1 CORO7 CRK DNM1 DNM2 EGFR ELF3 EPN1 EPN2 GRB2 HGS ITSN1 ITSN2 LAPTM5 MOB4 NAGPA NEDD4 NUMB NUMBL OPTN PARK2 REPS2 RNF11 SCAMP1 SNAP91 SPG20 STAM2 STAMBP STON2 SYNJ1 TFAP2A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H UBQLN1	8 interactors: AP2A2 AP2B1 EPS15 NECAP1 OGT PLCG1 TRAF3IP1 TUBA1B
Entrez ID		2060	9892
HPRD ID		08968	06391
Ensembl ID		ENSG00000085832	ENSG00000065609
Uniprot IDs		B1AUU8 B7Z240 H7BYP0 P42566	B7Z2N2 O60641
PDB IDs		1C07 1EH2 1F8H 1FF1 2IV9 2JXC
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Endocytosis Vesicle-mediated Transport Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Protein K48-linked Ubiquitination Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Signal Transduction Protein Polyubiquitination Negative Regulation Of Signaling Regulation Of Signal Transduction Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Signaling Cell Communication Transport Post-Golgi Vesicle-mediated Transport Cellular Localization Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Neuron Development Neurotrophin TRK Receptor Signaling Pathway Neuron Projection Development Establishment Of Localization In Cell Neuron Projection Morphogenesis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Neurotrophin Signaling Pathway Intracellular Transport Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Neuron Differentiation Cell Surface Receptor Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Cellular Response To Growth Factor Stimulus Establishment Of Protein Localization Response To Growth Factor Regulation Of Intracellular Signal Transduction Ephrin Receptor Signaling Pathway Protein Modification By Small Protein Conjugation Cellular Response To Hypoxia Protein Monoubiquitination Protein Catabolic Process Cellular Response To Decreased Oxygen Levels Receptor Internalization Protein Targeting To Lysosome	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Endocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Defense Response To Virus Regulation Of Immune System Process Regulation Of Defense Response To Virus By Virus Vesicle-mediated Transport Neurotrophin TRK Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurotrophin Signaling Pathway Intracellular Transport Regulation Of Signal Transduction Clathrin-mediated Endocytosis Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Signaling Transport Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organic Substance Establishment Of Localization In Cell Axon Guidance Cell Morphogenesis Negative Regulation Of Signal Transduction Cell Projection Organization Negative Regulation Of Signaling Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Cellular Localization Ephrin Receptor Signaling Pathway Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Axonogenesis Response To Organic Substance Viral Process Protein Transport Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Establishment Of Protein Localization Chemotaxis Response To Growth Factor Movement Of Cell Or Subcellular Component Cytoskeleton-dependent Intracellular Transport Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Response To External Stimulus
Tagcloud ?		6g4 adaptin adaptins ap cerevisiae clathrin coimmunoprecipitated delineated end3 endocytosis glutathione homology immunoprecipitates immunoreactivity kd keeping mammals metabolically mu2 nh2 nih3t3 pheromone polypeptides precipitated saccharomyces sets sigma transferase ubiquitous
Tagcloud (Difference) ?		6g4 adaptin adaptins ap cerevisiae clathrin coimmunoprecipitated delineated end3 endocytosis glutathione homology immunoprecipitates immunoreactivity kd keeping mammals metabolically mu2 nh2 nih3t3 pheromone polypeptides precipitated saccharomyces sets sigma transferase ubiquitous
Tagcloud (Intersection) ?