NUMB and PRKCZ

  • Number of citations of the paper that reports this interaction (PMID 17203073)
  • 60
  • Data Source:
  • BioGRID (enzymatic study, pull down)
  • HPRD (in vitro)

NUMB

PRKCZ

Gene Name numb homolog (Drosophila) protein kinase C, zeta
Image No pdb structure No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Bipolar disorder (mood-incongruent) ( 23092984)
  • Coronary artery calcification ( 17903303)
Protein-Protein Interactions 24 interactors: AP2A1 AP2A2 APP DPYSL2 EGFR EPS15 ITCH ITGB2 ITGB3 ITGB5 L1CAM LNX1 LNX2 MDM2 NOTCH1 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCZ RPL3 SIAH1 84 interactors: ADAP1 ADCY5 AFAP1 AKT1 AKT3 BTK C1QBP CASP3 CASP6 CASP7 CASP8 CASP9 CCDC115 CDC42 CHAT CSNK2B DAPK3 DENND5A FADD FEZ1 FEZ2 FRS2 FYN GLRX3 GRB14 GRM5 GSK3A GSK3B HABP4 HIST1H1A HIST1H1B HIST3H3 HRAS IKBKB IL4R IRAK1 IRS1 IRS4 JAK1 KRT10 LRRK2 MAP2K1 MAP2K5 MAPK1 MAPK3 MAPK7 MARCKS MBP NCF1 NCL NCOA3 NFATC2 NMT2 NUMB PARD6A PARD6B PARD6G PAWR PDLIM7 PDPK1 PEBP1 PPP1R14A PPP3CA PRG2 PRKCA PRKCD PSEN1 RAF1 RELA RHOA SLC39A1 SP1 SQSTM1 SRC STAT6 STUB1 TIAM1 TRAF6 UTP14A WWC1 YWHAB YWHAQ YWHAZ ZNF71
Entrez ID 8650 5590
HPRD ID 04767 01504
Ensembl ID ENSG00000133961 ENSG00000067606
Uniprot IDs P49757 Q05513
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adapter  affinities  arise  asymmetric  bind  bond  contain  diverse  division  domain  gp  gppy  helical  hydrogen  ldnpay  library  lnx  modes  motif  nak  nmr  npxy  peptide  phosphotyrosine  ptb  reveals  sheet  turn  y 
apical  blastocyst  cdx2  compaction  dampened  derives  erm  gtpases  hippo  icm  lats1  lineages  llgl1  nanog  outer  pard6b  phosphorylating  polarity  polarization  rho  rock  scrib  segregation  specification  specifying  te  trophectoderm  tyrosinated  yap 
Tagcloud (Difference) ?
adapter  affinities  arise  asymmetric  bind  bond  contain  diverse  division  domain  gp  gppy  helical  hydrogen  ldnpay  library  lnx  modes  motif  nak  nmr  npxy  peptide  phosphotyrosine  ptb  reveals  sheet  turn  y 
apical  blastocyst  cdx2  compaction  dampened  derives  erm  gtpases  hippo  icm  lats1  lineages  llgl1  nanog  outer  pard6b  phosphorylating  polarity  polarization  rho  rock  scrib  segregation  specification  specifying  te  trophectoderm  tyrosinated  yap 
Tagcloud (Intersection) ?