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PCM1 and EXOC8
Number of citations of the paper that reports this interaction (PMID
16189514
)
699
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PCM1
EXOC8
Gene Name
pericentriolar material 1
exocyst complex component 8
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Pericentriolar Material
Cytoplasm
Centrosome
Cytosol
Membrane
Nonmotile Primary Cilium
Nuclear Membrane
Centriolar Satellite
Ciliary Basal Body
Protein Complex
Exocyst
Cytoplasm
Late Endosome
Cytosol
Plasma Membrane
Membrane
Growth Cone
Molecular Function
Protein Binding
Identical Protein Binding
Protein Binding
Ral GTPase Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Organelle Organization
Interkinetic Nuclear Migration
Cytoplasmic Microtubule Organization
Microtubule Anchoring
Microtubule Anchoring At Centrosome
Intraciliary Transport Involved In Cilium Morphogenesis
Cilium Assembly
Negative Regulation Of Neurogenesis
Centrosome Organization
Protein Localization To Centrosome
Positive Regulation Of Intracellular Protein Transport
Neuronal Stem Cell Maintenance
Exocyst Assembly
Organelle Organization
Endosome Organization
Protein Transport
Extracellular Matrix Disassembly
Cellular Protein Metabolic Process
Exocyst Localization
Membrane Organization
Pathways
Organelle biogenesis and maintenance
Loss of proteins required for interphase microtubule organization from the centrosome
Loss of Nlp from mitotic centrosomes
G2/M Transition
Assembly of the primary cilium
Centrosome maturation
Regulation of PLK1 Activity at G2/M Transition
Mitotic G2-G2/M phases
Anchoring of the basal body to the plasma membrane
Recruitment of mitotic centrosome proteins and complexes
Cell Cycle, Mitotic
Peptide hormone metabolism
Cargo trafficking to the periciliary membrane
Organelle biogenesis and maintenance
Translocation of GLUT4 to the plasma membrane
VxPx cargo-targeting to cilium
Assembly of the primary cilium
Insulin processing
Drugs
Diseases
GWAS
Economic and political preferences (
22566634
)
Protein-Protein Interactions
17 interactors:
ABI2
BBS4
CASK
CCDC53
CEP131
CEP72
E2F4
EPS8
EXOC8
HAP1
ING5
KIAA0368
KRT15
KRT19
PCNT
TTC8
YWHAQ
20 interactors:
BLOC1S6
CCDC85B
CEP57L1
EFHC2
EXOC2
HGS
IKZF3
KRT15
KRT18
KRT19
KRT20
KRT31
LNX1
MBIP
PCM1
RAB3IL1
RALA
TADA2A
ULK1
USHBP1
Entrez ID
5108
149371
HPRD ID
02624
09943
Ensembl ID
ENSG00000078674
ENSG00000116903
Uniprot IDs
A2RUU9
E7ETA6
Q15154
Q8IYI6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Organelle Organization
Cilium Organization
Cilium Morphogenesis
Mitotic Cell Cycle
Positive Regulation Of Cilium Assembly
Sensory Processing
Cell Cycle Process
Mitotic Cell Cycle Process
Cilium Assembly
Cell Projection Organization
Microtubule-based Process
Organelle Assembly
Cell Cycle
Regulation Of Organelle Organization
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Cell Projection Assembly
Regulation Of Microtubule-based Movement
Cellular Protein Complex Localization
Rac Protein Signal Transduction
Organ Development
Nonmotile Primary Cilium Assembly
G2/M Transition Of Mitotic Cell Cycle
Cytoskeleton Organization
Protein Complex Localization
Anatomical Structure Development
Regulation Of Cilium Assembly
Positive Regulation Of Transport
Positive Regulation Of Organelle Assembly
Brain Development
Positive Regulation Of Organelle Organization
Cellular Component Assembly
Head Development
Regulation Of Intracellular Transport
Cell Projection Morphogenesis
Regulation Of Microtubule-based Process
Forebrain Development
Cell Part Morphogenesis
Developmental Process
Movement Of Cell Or Subcellular Component
Olfactory Bulb Development
Brain Morphogenesis
Central Nervous System Development
Multicellular Organismal Development
Olfactory Lobe Development
Eye Photoreceptor Cell Differentiation
Positive Regulation Of Intracellular Transport
Anatomical Structure Formation Involved In Morphogenesis
Cell Morphogenesis
Positive Regulation Of Neurotrophin Production
Organelle Organization
Protein Localization
Post-Golgi Vesicle-mediated Transport
Cytoskeleton Organization
Golgi To Plasma Membrane Transport
Membrane Organization
Intermediate Filament Cytoskeleton Organization
Intermediate Filament-based Process
Microtubule Anchoring
Histone H3 Acetylation
Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway
Golgi To Plasma Membrane CFTR Protein Transport
Golgi Vesicle Transport
Cellular Localization
Cytoplasmic Transport
Radial Glia Guided Migration Of Cerebellar Granule Cell
Exocytosis
Establishment Of Localization In Cell
Membrane Raft Localization
Protein Transport
Histone Acetylation
Vesicle-mediated Transport
Establishment Of Protein Localization
Internal Peptidyl-lysine Acetylation
Regulation Of Tubulin Deacetylation
Peptidyl-lysine Acetylation
Internal Protein Amino Acid Acetylation
Intracellular Transport
Maintenance Of Protein Location In Cell
Intraciliary Transport Involved In Cilium Morphogenesis
Secretion Of Lysosomal Enzymes
Microtubule-based Transport
Protein Acetylation
Maintenance Of Protein Location
Regulation Of Cell Differentiation
Cytoskeleton-dependent Intracellular Transport
Maintenance Of Location In Cell
Organelle Assembly
Negative Regulation Of Collateral Sprouting
Tagcloud
?
9p24
allogeneic
asct
band
bcr
bridging
cytogenetic
discovery
encouraging
fusion
guide
hematologic
highlight
indispensable
jak1
jak2
myeloid
neoplasms
occurring
ongoing
options
p22
p24
q11
rearrangements
remission
ruxolitinib
termed
usually
Tagcloud (Difference)
?
9p24
allogeneic
asct
band
bcr
bridging
cytogenetic
discovery
encouraging
fusion
guide
hematologic
highlight
indispensable
jak1
jak2
myeloid
neoplasms
occurring
ongoing
options
p22
p24
q11
rearrangements
remission
ruxolitinib
termed
usually
Tagcloud (Intersection)
?