PCM1 and KIAA0368

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PCM1	KIAA0368
Gene Name		pericentriolar material 1	KIAA0368
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Pericentriolar Material Cytoplasm Centrosome Cytosol Membrane Nonmotile Primary Cilium Nuclear Membrane Centriolar Satellite Ciliary Basal Body Protein Complex	Proteasome Complex Nucleus Early Endosome Late Endosome Multivesicular Body Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Trans-Golgi Network Centrosome Membrane Cytoplasmic Membrane-bounded Vesicle ER To Golgi Transport Vesicle Endocytic Vesicle
	Molecular Function	Protein Binding Identical Protein Binding	Molecular_function
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Interkinetic Nuclear Migration Cytoplasmic Microtubule Organization Microtubule Anchoring Microtubule Anchoring At Centrosome Intraciliary Transport Involved In Cilium Morphogenesis Cilium Assembly Negative Regulation Of Neurogenesis Centrosome Organization Protein Localization To Centrosome Positive Regulation Of Intracellular Protein Transport Neuronal Stem Cell Maintenance	ER-associated Ubiquitin-dependent Protein Catabolic Process
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Economic and political preferences ( 22566634)
Protein-Protein Interactions		17 interactors: ABI2 BBS4 CASK CCDC53 CEP131 CEP72 E2F4 EPS8 EXOC8 HAP1 ING5 KIAA0368 KRT15 KRT19 PCNT TTC8 YWHAQ	28 interactors: AGTRAP ANK2 ANKRD17 CCDC57 CEP170B CKS1B CMTM5 CPD DNAJB9 DST FBXO2 GAREML GOLGB1 HNRNPM MKI67 MYH10 PCM1 PCYT1B RAB11FIP4 RNF168 SF3B2 SPECC1L SYNE1 UBE2G2 UBE2Q1 UIMC1 VPS11 ZNF483
Entrez ID		5108	23392
HPRD ID		02624	11078
Ensembl ID		ENSG00000078674	ENSG00000136813
Uniprot IDs		A2RUU9 E7ETA6 Q15154	J3KN16 Q5VYK3
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Cilium Organization Cilium Morphogenesis Mitotic Cell Cycle Positive Regulation Of Cilium Assembly Sensory Processing Cell Cycle Process Mitotic Cell Cycle Process Cilium Assembly Cell Projection Organization Microtubule-based Process Organelle Assembly Cell Cycle Regulation Of Organelle Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Projection Assembly Regulation Of Microtubule-based Movement Cellular Protein Complex Localization Rac Protein Signal Transduction Organ Development Nonmotile Primary Cilium Assembly G2/M Transition Of Mitotic Cell Cycle Cytoskeleton Organization Protein Complex Localization Anatomical Structure Development Regulation Of Cilium Assembly Positive Regulation Of Transport Positive Regulation Of Organelle Assembly Brain Development Positive Regulation Of Organelle Organization Cellular Component Assembly Head Development Regulation Of Intracellular Transport Cell Projection Morphogenesis Regulation Of Microtubule-based Process Forebrain Development Cell Part Morphogenesis Developmental Process Movement Of Cell Or Subcellular Component Olfactory Bulb Development Brain Morphogenesis Central Nervous System Development Multicellular Organismal Development Olfactory Lobe Development Eye Photoreceptor Cell Differentiation Positive Regulation Of Intracellular Transport Anatomical Structure Formation Involved In Morphogenesis Cell Morphogenesis Positive Regulation Of Neurotrophin Production	ER-associated Ubiquitin-dependent Protein Catabolic Process Nucleus Localization Cell Cycle Establishment Of Nucleus Localization Cell Cycle Process Positive Regulation Of DNA Repair Cell Division Endomembrane System Organization Negative Regulation Of Muscle Cell Differentiation Histone H2A-K13 Ubiquitination Protein Localization To T-tubule Histone H2A-K15 Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Regulation Of DNA Repair Histone H2A K63-linked Ubiquitination T-tubule Organization Protein Localization To M-band Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Response To DNA Damage Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process
Tagcloud ?		9p24 allogeneic asct band bcr bridging cytogenetic discovery encouraging fusion guide hematologic highlight indispensable jak1 jak2 myeloid neoplasms occurring ongoing options p22 p24 q11 rearrangements remission ruxolitinib termed usually
Tagcloud (Difference) ?		9p24 allogeneic asct band bcr bridging cytogenetic discovery encouraging fusion guide hematologic highlight indispensable jak1 jak2 myeloid neoplasms occurring ongoing options p22 p24 q11 rearrangements remission ruxolitinib termed usually
Tagcloud (Intersection) ?