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LNX1 and SUV39H2
Number of citations of the paper that reports this interaction (PMID
23455924
)
3
Data Source:
BioGRID
(two hybrid)
LNX1
SUV39H2
Gene Name
ligand of numb-protein X 1, E3 ubiquitin protein ligase
suppressor of variegation 3-9 homolog 2 (Drosophila)
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Chromosome, Centromeric Region
Chromatin
Nucleoplasm
Nuclear Heterochromatin
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
PDZ Domain Binding
Transcription Regulatory Region Sequence-specific DNA Binding
Chromatin Binding
Protein Binding
Zinc Ion Binding
Histone Methyltransferase Activity (H3-K9 Specific)
Biological Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein Homooligomerization
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Chromatin Organization
Chromatin Assembly Or Disassembly
Chromatin Remodeling
Transcription, DNA-templated
Male Meiosis
Cell Differentiation
Histone H3-K9 Dimethylation
Histone H3-K9 Trimethylation
Negative Regulation Of Circadian Rhythm
Negative Regulation Of Transcription, DNA-templated
Rhythmic Process
Cellular Response To Hypoxia
Pathways
Chromatin modifying enzymes
Chromatin organization
PKMTs methylate histone lysines
Drugs
Diseases
GWAS
DNA methylation (variation) (
23725790
)
Protein-Protein Interactions
218 interactors:
ABCA1
ABCB1
ABR
ACAT2
ACY3
ADRA1D
AGTRAP
AIDA
AIMP2
AKIRIN2
ALDOC
ALKBH3
AMMECR1L
APIP
APOL4
APP
ARHGAP6
ARHGEF16
ARVCF
ATPAF2
ATRIP
AURKC
BCR
BLVRA
BPIFA1
C1QTNF1
CA8
CALCOCO2
CAMK2N2
CATSPERD
CCDC101
CCDC102B
CCDC114
CCDC85B
CDA
CDC42EP4
CEP72
CGN
CIB3
CIRBP
CITED1
CLDN1
CLDN17
CLDN2
CLK2
COIL
CPNE2
CTBP1
CTNND2
CTSO
CUTC
CXADR
DAB1
DAPK1
DCTD
DCUN1D5
DDX17
DEPTOR
DNPEP
DOCK9
DPF2
DVL3
EBF4
EHMT2
EIF4H
ENOX1
EPHB3
EXOC8
FAM118A
FAM124A
FAM212B
FAM9B
FBP1
FBXL12
FHL3
GAS2L2
GDI1
GIPR
GJD4
GOLPH3L
GPR142
GRB2
GRIN1
HMBOX1
HOMEZ
HSBP1
HTR2B
HUNK
IGSF5
IL3RA
ILF3
INSC
ISCU
JOSD1
KALRN
KCNA4
KCTD1
KCTD13
KCTD17
KCTD6
KHDRBS3
KIAA1598
KLHL12
KRT15
KRTAP4-12
KRTAP4-2
KRTAP9-2
KXD1
LCLAT1
LDOC1
LGALS14
LGR6
LNX2
LRRC3B
LSM2
MAGEA11
MAGEB18
MAPK9
MEMO1
METTL21A
MRFAP1L1
MRPS24
MTMR9
MTUS2
MUSTN1
MVB12B
NADK
NAGK
NCK2
NECAB2
NEK6
NKD2
NME7
NOTCH2NL
NRCAM
NUDT14
NUMB
NUP37
NXT2
ORMDL3
OSBP2
OSGIN1
PAFAH1B3
PAICS
PBK
PBLD
PCBD1
PDZRN3
PDZRN4
PKDREJ
PKM
PKP4
POMGNT1
PPIA
PPID
PQBP1
PRR13
PTGIR
PTS
RABAC1
RAD51D
RAD54B
RBMX
RBMY1A1
RFPL3
ROBO3
ROPN1
RPIA
RUFY4
RUVBL2
SAPCD1
SAT1
SCLT1
SDK1
SLC6A15
SLC6A5
SNCB
SNRNP25
SNRPF
SPHKAP
SRSF1
SSNA1
SSTR3
STAC2
STRN
STX5
SUV39H1
SUV39H2
TBCEL
THAP7
TIFA
TMEM14C
TNFRSF18
TPM4
TRAF2
TRIM23
TRIM39
TRIM54
TRIP13
TRMT12
TSC2
TSC22D4
TSSK3
TYRO3
UBE2D2
ULK2
VCP
VRK2
WAC
WNT8A
WWP1
ZADH2
ZBTB43
ZBTB8A
ZCCHC10
ZFP64
ZNF581
ZNF593
39 interactors:
AKAP9
APPL2
BLZF1
C8orf74
CBX5
CBX7
CCDC151
CCDC37
CDCA4
CEP70
CGGBP1
EWSR1
FAM20C
GSTCD
ID2
KCTD17
KLF3
KLHDC4
LCA5L
LNX1
LRIF1
MCM3AP
MRFAP1
MTF2
MYL12A
NME4
PHF19
PNMA1
POLR3F
RAB3IP
RASSF1
SHC1
SMAD5
SNF8
UBE2V2
WIZ
ZNF212
ZNF557
ZNF57
Entrez ID
84708
79723
HPRD ID
17287
07580
Ensembl ID
ENSG00000072201
ENSG00000152455
Uniprot IDs
Q8TBB1
Q9H5I1
PDB IDs
3B76
2R3A
Enriched GO Terms of Interacting Partners
?
Cellular Component Assembly
Protein Homooligomerization
Protein Oligomerization
Protein Complex Assembly
Regulation Of Signal Transduction
Regulation Of Signaling
Regulation Of Cellular Process
Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Process
Regulation Of Cellular Component Organization
Cellular Aromatic Compound Metabolic Process
Regulation Of Rho Protein Signal Transduction
Response To Stimulus
Developmental Process
Cellular Metabolic Process
Peptidyl-lysine Dimethylation
Heterocycle Metabolic Process
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Neutrophil Degranulation
Cellular Response To Stimulus
Viral Process
Programmed Cell Death
Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Splicing
Cellular Nitrogen Compound Metabolic Process
Protein Tetramerization
Cell Death
Apoptotic Process
Death
Neuron Recognition
Cell Communication
Signaling
Regulation Of Neutrophil Degranulation
Negative Regulation Of Neutrophil Activation
Viral Release From Host Cell
Regulation Of Rho GTPase Activity
Cell-cell Junction Organization
Protein Autophosphorylation
Response To Abiotic Stimulus
Organelle Organization
Regulation Of Cell Morphogenesis
Nitrogen Compound Metabolic Process
Axon Midline Choice Point Recognition
Positive Regulation Of Rho GTPase Activity
Cell Morphogenesis Involved In Differentiation
Regulation Of Protein Homodimerization Activity
Regulation Of Ras Protein Signal Transduction
Protein Heterooligomerization
Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Cellular Process
Positive Regulation Of Histone H3-K27 Methylation
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Histone H3-K27 Methylation
Regulation Of RNA Metabolic Process
Gene Expression
Nucleobase-containing Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Osteoblast Differentiation
Biosynthetic Process
Regulation Of Epidermal Growth Factor-activated Receptor Activity
Golgi To Plasma Membrane Transport
Positive Regulation Of Histone Methylation
Nitrogen Compound Metabolic Process
Positive Regulation Of DNA Metabolic Process
Osteoclast Maturation
Regulation Of Histone Methylation
Regulation Of Ossification
Protein Targeting
Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription, DNA-templated
Regulation Of Protein Tyrosine Kinase Activity
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of RNA Biosynthetic Process
Establishment Of Protein Localization To Membrane
Positive Regulation Of DNA Replication
Positive Regulation Of Histone Modification
Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Positive Regulation Of Osteoblast Differentiation
Myeloid Cell Differentiation
Negative Regulation Of Gene Expression, Epigenetic
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Establishment Of Protein Localization To Plasma Membrane
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Tagcloud
?
a7
circular
dichroism
dim
g12
g13
g9a
h3k9
h3k9me0
h3k9me1
h3k9me2
h3k9me3
introduce
introduces
k14
labrador
n324k
pkmts
prefers
processive
r8
readout
recognizes
renders
retrievers
s10
t11
t6
Tagcloud (Difference)
?
a7
circular
dichroism
dim
g12
g13
g9a
h3k9
h3k9me0
h3k9me1
h3k9me2
h3k9me3
introduce
introduces
k14
labrador
n324k
pkmts
prefers
processive
r8
readout
recognizes
renders
retrievers
s10
t11
t6
Tagcloud (Intersection)
?