SUV39H2 and C8orf74

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (two hybrid)

		SUV39H2	C8orf74
Description		SUV39H2 histone lysine methyltransferase	chromosome 8 open reading frame 74
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome
	Molecular Function	Transcription Cis-regulatory Region Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Metal Ion Binding Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity S-adenosyl-L-methionine Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Circadian Rhythm Cell Differentiation Methylation Epigenetic Programming In The Zygotic Pronuclei Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Hypoxia
Pathways		PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Alanine aminotransferase levels ( 33547301) Autism spectrum disorder ( 30804558) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Fish- and plant-related diet ( 32066663) Processed meat consumption ( 32066663) Suicide ( 26079190)
Interacting Genes		43 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD H3C1 ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 VHL WIZ ZNF212 ZNF557 ZNF57	8 interacting genes: KDM1A PRMT6 SUV39H1 SUV39H2 TRIM54 TRIM55 TRIM63 ZNF655
Entrez ID		79723	203076
HPRD ID		07580	19096
Ensembl ID		ENSG00000152455	ENSG00000171060
Uniprot IDs		Q9H5I1	A0AAG2TK55 Q6P047
PDB IDs		2R3A 6P0R
Enriched GO Terms of Interacting Partners?		Nucleoplasm Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone H3K36me3 Reader Activity Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding	Histone H3 Methyltransferase Activity Defense Response To Other Organism Defense Response To Symbiont Histone Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity Innate Immune Response Response To Other Organism Immune Response Response To Stress Histone H3K9 Methyltransferase Activity Response To External Biotic Stimulus Defense Response Epigenetic Programming In The Zygotic Pronuclei Defense Response To Bacterium Response To Bacterium Methyltransferase Activity Immune System Process Epigenetic Programming Of Gene Expression Methylation Histone H2AR3 Methyltransferase Activity Epigenetic Regulation Of Gene Expression Chromatin Remodeling Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Histone H3R2 Methyltransferase Activity Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation ENoSc Complex Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Histone Arginine N-methyltransferase Activity Microtubule Defense Response To Gram-negative Bacterium Zinc Ion Binding Ubiquitin Protein Ligase Activity Protein Demethylase Activity CCR2 Chemokine Receptor Binding RDNA Heterochromatin Chromatin Organization MRF Binding Protein-arginine Omega-N Monomethyltransferase Activity Histone H4R3 Methyltransferase Activity Skeletal Muscle Atrophy Defense Response To Gram-positive Bacterium Regulation Of Signal Transduction By P53 Class Mediator
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?