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LNX1 and RUVBL2
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
LNX1
RUVBL2
Gene Name
ligand of numb-protein X 1, E3 ubiquitin protein ligase
RuvB-like AAA ATPase 2
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Swr1 Complex
Intracellular
Nucleus
Nucleoplasm
Nuclear Euchromatin
Cytoplasm
Membrane
Nuclear Matrix
Ribonucleoprotein Complex
Ino80 Complex
NuA4 Histone Acetyltransferase Complex
Extracellular Vesicular Exosome
MLL1 Complex
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
PDZ Domain Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding
DNA Helicase Activity
Damaged DNA Binding
ATP-dependent DNA Helicase Activity
Protein Binding
ATP Binding
ATPase Activity
Chromatin DNA Binding
Identical Protein Binding
ATP-dependent 5'-3' DNA Helicase Activity
Unfolded Protein Binding
Biological Process
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Protein Homooligomerization
DNA Repair
DNA Recombination
Chromatin Organization
Chromatin Remodeling
Transcription, DNA-templated
Protein Folding
DNA Duplex Unwinding
Cellular Response To UV
Positive Regulation Of Histone Acetylation
Regulation Of Growth
Histone H4 Acetylation
Histone H2A Acetylation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Establishment Of Protein Localization To Chromatin
Cellular Response To Estradiol Stimulus
Transcriptional Activation By Promoter-enhancer Looping
Negative Regulation Of Estrogen Receptor Binding
Pathways
Chromatin modifying enzymes
Telomere Maintenance
Chromosome Maintenance
Chromatin organization
Extension of Telomeres
Telomere Extension By Telomerase
HATs acetylate histones
Drugs
Diseases
GWAS
DNA methylation (variation) (
23725790
)
Protein-Protein Interactions
218 interactors:
ABCA1
ABCB1
ABR
ACAT2
ACY3
ADRA1D
AGTRAP
AIDA
AIMP2
AKIRIN2
ALDOC
ALKBH3
AMMECR1L
APIP
APOL4
APP
ARHGAP6
ARHGEF16
ARVCF
ATPAF2
ATRIP
AURKC
BCR
BLVRA
BPIFA1
C1QTNF1
CA8
CALCOCO2
CAMK2N2
CATSPERD
CCDC101
CCDC102B
CCDC114
CCDC85B
CDA
CDC42EP4
CEP72
CGN
CIB3
CIRBP
CITED1
CLDN1
CLDN17
CLDN2
CLK2
COIL
CPNE2
CTBP1
CTNND2
CTSO
CUTC
CXADR
DAB1
DAPK1
DCTD
DCUN1D5
DDX17
DEPTOR
DNPEP
DOCK9
DPF2
DVL3
EBF4
EHMT2
EIF4H
ENOX1
EPHB3
EXOC8
FAM118A
FAM124A
FAM212B
FAM9B
FBP1
FBXL12
FHL3
GAS2L2
GDI1
GIPR
GJD4
GOLPH3L
GPR142
GRB2
GRIN1
HMBOX1
HOMEZ
HSBP1
HTR2B
HUNK
IGSF5
IL3RA
ILF3
INSC
ISCU
JOSD1
KALRN
KCNA4
KCTD1
KCTD13
KCTD17
KCTD6
KHDRBS3
KIAA1598
KLHL12
KRT15
KRTAP4-12
KRTAP4-2
KRTAP9-2
KXD1
LCLAT1
LDOC1
LGALS14
LGR6
LNX2
LRRC3B
LSM2
MAGEA11
MAGEB18
MAPK9
MEMO1
METTL21A
MRFAP1L1
MRPS24
MTMR9
MTUS2
MUSTN1
MVB12B
NADK
NAGK
NCK2
NECAB2
NEK6
NKD2
NME7
NOTCH2NL
NRCAM
NUDT14
NUMB
NUP37
NXT2
ORMDL3
OSBP2
OSGIN1
PAFAH1B3
PAICS
PBK
PBLD
PCBD1
PDZRN3
PDZRN4
PKDREJ
PKM
PKP4
POMGNT1
PPIA
PPID
PQBP1
PRR13
PTGIR
PTS
RABAC1
RAD51D
RAD54B
RBMX
RBMY1A1
RFPL3
ROBO3
ROPN1
RPIA
RUFY4
RUVBL2
SAPCD1
SAT1
SCLT1
SDK1
SLC6A15
SLC6A5
SNCB
SNRNP25
SNRPF
SPHKAP
SRSF1
SSNA1
SSTR3
STAC2
STRN
STX5
SUV39H1
SUV39H2
TBCEL
THAP7
TIFA
TMEM14C
TNFRSF18
TPM4
TRAF2
TRIM23
TRIM39
TRIM54
TRIP13
TRMT12
TSC2
TSC22D4
TSSK3
TYRO3
UBE2D2
ULK2
VCP
VRK2
WAC
WNT8A
WWP1
ZADH2
ZBTB43
ZBTB8A
ZCCHC10
ZFP64
ZNF581
ZNF593
27 interactors:
APP
APPL1
APPL2
ATF2
BCL3
CCDC103
CDKN2A
CTNNB1
DPCD
EHMT2
EXOSC10
FBL
FDFT1
HDAC1
HDAC4
LIG4
LNX1
MDM2
NDRG1
NUFIP1
PIH1D1
RUVBL1
STOM
TAF9
TBP
TERT
YWHAQ
Entrez ID
84708
10856
HPRD ID
17287
16070
Ensembl ID
ENSG00000072201
ENSG00000183207
Uniprot IDs
Q8TBB1
B3KNL2
B3KQ59
Q9Y230
PDB IDs
3B76
2CQA
2XSZ
3UK6
Enriched GO Terms of Interacting Partners
?
Cellular Component Assembly
Protein Homooligomerization
Protein Oligomerization
Protein Complex Assembly
Regulation Of Signal Transduction
Regulation Of Signaling
Regulation Of Cellular Process
Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Cellular Process
Regulation Of Cellular Component Organization
Cellular Aromatic Compound Metabolic Process
Regulation Of Rho Protein Signal Transduction
Response To Stimulus
Developmental Process
Cellular Metabolic Process
Peptidyl-lysine Dimethylation
Heterocycle Metabolic Process
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Neutrophil Degranulation
Cellular Response To Stimulus
Viral Process
Programmed Cell Death
Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Splicing
Cellular Nitrogen Compound Metabolic Process
Protein Tetramerization
Cell Death
Apoptotic Process
Death
Neuron Recognition
Cell Communication
Signaling
Regulation Of Neutrophil Degranulation
Negative Regulation Of Neutrophil Activation
Viral Release From Host Cell
Regulation Of Rho GTPase Activity
Cell-cell Junction Organization
Protein Autophosphorylation
Response To Abiotic Stimulus
Organelle Organization
Regulation Of Cell Morphogenesis
Nitrogen Compound Metabolic Process
Axon Midline Choice Point Recognition
Positive Regulation Of Rho GTPase Activity
Cell Morphogenesis Involved In Differentiation
Regulation Of Protein Homodimerization Activity
Regulation Of Ras Protein Signal Transduction
Protein Heterooligomerization
Biosynthetic Process
Chromatin Modification
Positive Regulation Of Gene Expression
Chromatin Organization
Chromosome Organization
Negative Regulation Of Cellular Metabolic Process
Regulation Of Gene Expression, Epigenetic
Histone Modification
Regulation Of Transcription From RNA Polymerase II Promoter
RNA Metabolic Process
Cellular Component Assembly
Peptidyl-lysine Modification
Apoptotic Process
Negative Regulation Of Gene Expression
Positive Regulation Of Transcription, DNA-templated
Programmed Cell Death
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cell Cycle
Cell Death
Death
Regulation Of Protein Sumoylation
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of Apoptotic Process
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Cell Death
Box C/D SnoRNP Assembly
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of Biosynthetic Process
Histone H3-K9 Modification
Developmental Process
Posttranscriptional Regulation Of Gene Expression
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Signal Transduction By P53 Class Mediator
Sexual Reproduction
Ribonucleoprotein Complex Biogenesis
Gene Expression
Cellular Response To DNA Damage Stimulus
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Apoptotic Process
Fungiform Papilla Formation
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Programmed Cell Death
Chromatin Remodeling
Tagcloud
?
ac
accessible
architecture
attenuates
baz1b
clarify
cytoprotective
foci
gammah2ax
h2ax
h3k56
h3k9
hubs
integrated
ints3
irradiation
isoform
mark
matrix
mount
prevents
proteomic
respond
runx
runx2
scaffolding
subnuclear
supported
Tagcloud (Difference)
?
ac
accessible
architecture
attenuates
baz1b
clarify
cytoprotective
foci
gammah2ax
h2ax
h3k56
h3k9
hubs
integrated
ints3
irradiation
isoform
mark
matrix
mount
prevents
proteomic
respond
runx
runx2
scaffolding
subnuclear
supported
Tagcloud (Intersection)
?