LNX1 and CITED1

Number of citations of the paper that reports this interaction (PMID 22889411)
1

Data Source:
BioGRID (two hybrid)

		LNX1	CITED1
Gene Name		ligand of numb-protein X 1, E3 ubiquitin protein ligase	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nucleus Cytoplasm Cytosol
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity PDZ Domain Binding	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Protein C-terminus Binding Protein Homodimerization Activity Transcription Regulatory Region DNA Binding LBD Domain Binding Co-SMAD Binding
	Biological Process	Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Homooligomerization	Embryonic Axis Specification Vasculogenesis Metanephros Development Branching Involved In Ureteric Bud Morphogenesis Placenta Development Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Nucleocytoplasmic Transport Apoptotic Process Transforming Growth Factor Beta Receptor Signaling Pathway Brain Development Cell Proliferation Positive Regulation Of Gene Expression Negative Regulation Of Wnt Signaling Pathway Melanocyte Differentiation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To Lipopolysaccharide Response To Insulin Response To Cytokine Response To Interferon-gamma Melanin Biosynthetic Process Pigmentation Negative Regulation Of Neuron Apoptotic Process Response To Estrogen Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Response To CAMP Mesenchymal To Epithelial Transition SMAD Protein Signal Transduction Labyrinthine Layer Development Spongiotrophoblast Layer Development Response To Interleukin-1 Response To Interleukin-2 Response To Interleukin-4 Response To Interleukin-6 Response To Interleukin-9 Response To Interleukin-11 Response To Parathyroid Hormone Response To Transforming Growth Factor Beta
Pathways
Drugs
Diseases
GWAS		DNA methylation (variation) ( 23725790)
Protein-Protein Interactions		218 interactors: ABCA1 ABCB1 ABR ACAT2 ACY3 ADRA1D AGTRAP AIDA AIMP2 AKIRIN2 ALDOC ALKBH3 AMMECR1L APIP APOL4 APP ARHGAP6 ARHGEF16 ARVCF ATPAF2 ATRIP AURKC BCR BLVRA BPIFA1 C1QTNF1 CA8 CALCOCO2 CAMK2N2 CATSPERD CCDC101 CCDC102B CCDC114 CCDC85B CDA CDC42EP4 CEP72 CGN CIB3 CIRBP CITED1 CLDN1 CLDN17 CLDN2 CLK2 COIL CPNE2 CTBP1 CTNND2 CTSO CUTC CXADR DAB1 DAPK1 DCTD DCUN1D5 DDX17 DEPTOR DNPEP DOCK9 DPF2 DVL3 EBF4 EHMT2 EIF4H ENOX1 EPHB3 EXOC8 FAM118A FAM124A FAM212B FAM9B FBP1 FBXL12 FHL3 GAS2L2 GDI1 GIPR GJD4 GOLPH3L GPR142 GRB2 GRIN1 HMBOX1 HOMEZ HSBP1 HTR2B HUNK IGSF5 IL3RA ILF3 INSC ISCU JOSD1 KALRN KCNA4 KCTD1 KCTD13 KCTD17 KCTD6 KHDRBS3 KIAA1598 KLHL12 KRT15 KRTAP4-12 KRTAP4-2 KRTAP9-2 KXD1 LCLAT1 LDOC1 LGALS14 LGR6 LNX2 LRRC3B LSM2 MAGEA11 MAGEB18 MAPK9 MEMO1 METTL21A MRFAP1L1 MRPS24 MTMR9 MTUS2 MUSTN1 MVB12B NADK NAGK NCK2 NECAB2 NEK6 NKD2 NME7 NOTCH2NL NRCAM NUDT14 NUMB NUP37 NXT2 ORMDL3 OSBP2 OSGIN1 PAFAH1B3 PAICS PBK PBLD PCBD1 PDZRN3 PDZRN4 PKDREJ PKM PKP4 POMGNT1 PPIA PPID PQBP1 PRR13 PTGIR PTS RABAC1 RAD51D RAD54B RBMX RBMY1A1 RFPL3 ROBO3 ROPN1 RPIA RUFY4 RUVBL2 SAPCD1 SAT1 SCLT1 SDK1 SLC6A15 SLC6A5 SNCB SNRNP25 SNRPF SPHKAP SRSF1 SSNA1 SSTR3 STAC2 STRN STX5 SUV39H1 SUV39H2 TBCEL THAP7 TIFA TMEM14C TNFRSF18 TPM4 TRAF2 TRIM23 TRIM39 TRIM54 TRIP13 TRMT12 TSC2 TSC22D4 TSSK3 TYRO3 UBE2D2 ULK2 VCP VRK2 WAC WNT8A WWP1 ZADH2 ZBTB43 ZBTB8A ZCCHC10 ZFP64 ZNF581 ZNF593	8 interactors: CREBBP EP300 ESR1 HSPA8 LNX1 SMAD4 TFAP2B TFAP2C
Entrez ID		84708	4435
HPRD ID		17287	02146
Ensembl ID		ENSG00000072201	ENSG00000125931
Uniprot IDs		Q8TBB1	Q99966
PDB IDs		3B76
Enriched GO Terms of Interacting Partners?		Cellular Component Assembly Protein Homooligomerization Protein Oligomerization Protein Complex Assembly Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Cellular Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Cellular Process Regulation Of Cellular Component Organization Cellular Aromatic Compound Metabolic Process Regulation Of Rho Protein Signal Transduction Response To Stimulus Developmental Process Cellular Metabolic Process Peptidyl-lysine Dimethylation Heterocycle Metabolic Process Regulation Of Intracellular Signal Transduction Negative Regulation Of Neutrophil Degranulation Cellular Response To Stimulus Viral Process Programmed Cell Death Nucleobase-containing Compound Metabolic Process Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process Protein Tetramerization Cell Death Apoptotic Process Death Neuron Recognition Cell Communication Signaling Regulation Of Neutrophil Degranulation Negative Regulation Of Neutrophil Activation Viral Release From Host Cell Regulation Of Rho GTPase Activity Cell-cell Junction Organization Protein Autophosphorylation Response To Abiotic Stimulus Organelle Organization Regulation Of Cell Morphogenesis Nitrogen Compound Metabolic Process Axon Midline Choice Point Recognition Positive Regulation Of Rho GTPase Activity Cell Morphogenesis Involved In Differentiation Regulation Of Protein Homodimerization Activity Regulation Of Ras Protein Signal Transduction Protein Heterooligomerization Biosynthetic Process	Negative Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Cellular Response To Heat Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated N-terminal Peptidyl-lysine Acetylation Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Negative Regulation Of Biosynthetic Process Anatomical Structure Morphogenesis Cellular Response To Heat Tube Development Germ-line Stem Cell Maintenance Branch Elongation Involved In Mammary Gland Duct Branching Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Transcription From RNA Polymerase II Promoter Sebaceous Gland Development Regulation Of Transcription From RNA Polymerase II Promoter Response To Heat N-terminal Protein Amino Acid Acetylation RNA Metabolic Process Organ Morphogenesis Positive Regulation Of Metabolic Process Epithelium Development Gene Expression Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Stem Cell Maintenance Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Mammary Gland Epithelial Cell Proliferation Branch Elongation Of An Epithelium Response To Temperature Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Branching Morphogenesis Of An Epithelial Tube Tissue Morphogenesis N-terminal Protein Amino Acid Modification Regulation Of Transcription, DNA-templated Skin Development DNA-templated Transcription, Initiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Morphogenesis Of A Branching Epithelium
Tagcloud ?			calm3 cblb ccna2 ccnd3 cdk6 dems dok elk3 fyn git1 hck lck module modules nonmodule p85beta pdgfra pib5pa psd93 ptch2 sam68 sh3kbp1 shc tgfbr1 tgfbr2 vav2 wilcoxon yes zfyve9
Tagcloud (Difference) ?			calm3 cblb ccna2 ccnd3 cdk6 dems dok elk3 fyn git1 hck lck module modules nonmodule p85beta pdgfra pib5pa psd93 ptch2 sam68 sh3kbp1 shc tgfbr1 tgfbr2 vav2 wilcoxon yes zfyve9
Tagcloud (Intersection) ?