SUV39H2 and MTF2

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (two hybrid)

		SUV39H2	MTF2
Description		SUV39H2 histone lysine methyltransferase	metal response element binding transcription factor 2
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome	Nucleus Nucleoplasm Cytoplasm ESC/E(Z) Complex
	Molecular Function	Transcription Cis-regulatory Region Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Metal Ion Binding Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity S-adenosyl-L-methionine Binding Ubiquitin-like Ligase-substrate Adaptor Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Binding DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K36me3 Reader Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Circadian Rhythm Cell Differentiation Methylation Epigenetic Programming In The Zygotic Pronuclei Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Hypoxia	Chromatin Organization Segment Specification Stem Cell Population Maintenance Epigenetic Regulation Of Gene Expression Negative Regulation Of Gene Expression, Epigenetic Stem Cell Differentiation Cellular Response To Leukemia Inhibitory Factor
Pathways		PKMTs methylate histone lysines	PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Bitter alcoholic beverage consumption ( 31046077) Chronotype ( 30696823) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Plasma clusterin levels ( 26545630) Response to lurasidone in schizophrenia ( 29730043) Triglyceride levels ( 32154731)
Interacting Genes		43 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD H3C1 ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 VHL WIZ ZNF212 ZNF557 ZNF57	12 interacting genes: CDKN2D CREB1 GPRASP1 GSK3B KDM1A PIK3R3 PRKD2 PRMT6 SMAD3 SUV39H1 SUV39H2 TMED9
Entrez ID		79723	22823
HPRD ID		07580	14342
Ensembl ID		ENSG00000152455	ENSG00000143033
Uniprot IDs		Q9H5I1	B4DZ69 B4DZG1 Q7Z534 Q9Y483
PDB IDs		2R3A 6P0R	5XFR
Enriched GO Terms of Interacting Partners?		Nucleoplasm Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone H3K36me3 Reader Activity Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding	Positive Regulation Of Transforming Growth Factor Beta3 Production Histone H3 Methyltransferase Activity Circadian Rhythm Histone Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Apoptotic Process Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Histone H3K9 Methyltransferase Activity Rhythmic Process Transcription Cis-regulatory Region Binding Regulation Of Growth Response To Retinoic Acid Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Transcription By RNA Polymerase II Response To Decreased Oxygen Levels Response To Hypoxia Epigenetic Programming In The Zygotic Pronuclei Regulation Of Epithelial To Mesenchymal Transition Response To Oxygen Levels Positive Regulation Of Transforming Growth Factor Beta Production Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Metabolic Process Regulation Of Multicellular Organismal Development Methyltransferase Activity Nucleoplasm Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Macromolecule Biosynthetic Process Chromatin Binding Epigenetic Programming Of Gene Expression Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II Methylation Regulation Of Striated Muscle Tissue Development Regulation Of Cellular Response To Stress Cell Differentiation Regulation Of Long-term Synaptic Potentiation Regulation Of Muscle Organ Development Regulation Of Developmental Process Positive Regulation Of Cell Migration Regulation Of Cellular Component Organization Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Cell Motility Regulation Of Cell Communication
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