SUV39H2 and KCTD17

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		SUV39H2	KCTD17
Gene Name		suppressor of variegation 3-9 homolog 2 (Drosophila)	potassium channel tetramerization domain containing 17
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleoplasm Nuclear Heterochromatin
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Histone Methyltransferase Activity (H3-K9 Specific)	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Chromatin Assembly Or Disassembly Chromatin Remodeling Transcription, DNA-templated Male Meiosis Cell Differentiation Histone H3-K9 Dimethylation Histone H3-K9 Trimethylation Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Cellular Response To Hypoxia	Protein Homooligomerization
Pathways		Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Red blood cell traits ( 23222517)
Protein-Protein Interactions		39 interactors: AKAP9 APPL2 BLZF1 C8orf74 CBX5 CBX7 CCDC151 CCDC37 CDCA4 CEP70 CGGBP1 EWSR1 FAM20C GSTCD ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MCM3AP MRFAP1 MTF2 MYL12A NME4 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 WIZ ZNF212 ZNF557 ZNF57	12 interactors: AQP1 DMC1 LNX1 LRRC18 NIF3L1 NUDT18 PSMA1 RWDD4 STK16 SUV39H2 TINF2 TUBGCP4
Entrez ID		79723	79734
HPRD ID		07580	07764
Ensembl ID		ENSG00000152455	ENSG00000100379
Uniprot IDs		Q9H5I1	Q8N5Z5
PDB IDs		2R3A
Enriched GO Terms of Interacting Partners?		Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Cellular Process Positive Regulation Of Histone H3-K27 Methylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Histone H3-K27 Methylation Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Osteoblast Differentiation Biosynthetic Process Regulation Of Epidermal Growth Factor-activated Receptor Activity Golgi To Plasma Membrane Transport Positive Regulation Of Histone Methylation Nitrogen Compound Metabolic Process Positive Regulation Of DNA Metabolic Process Osteoclast Maturation Regulation Of Histone Methylation Regulation Of Ossification Protein Targeting Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription, DNA-templated Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process Establishment Of Protein Localization To Membrane Positive Regulation Of DNA Replication Positive Regulation Of Histone Modification Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Positive Regulation Of Osteoblast Differentiation Myeloid Cell Differentiation Negative Regulation Of Gene Expression, Epigenetic Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Establishment Of Protein Localization To Plasma Membrane Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition	Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Male Meiosis Negative Regulation Of Protein ADP-ribosylation Metanephric Descending Thin Limb Development DGDP Catabolic Process Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development DADP Catabolic Process Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport GDP Catabolic Process Response To Brefeldin A Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Protein ADP-ribosylation Carbon Dioxide Transmembrane Transport Corticotropin Secretion 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Establishment Or Maintenance Of Actin Cytoskeleton Polarity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Oxygen Levels Metanephric Proximal Convoluted Tubule Development Nitric Oxide Transport Dihydrobiopterin Metabolic Process Cellular Response To Mercury Ion Cell Cycle Metanephric Proximal Tubule Development Negative Regulation Of Protein Glycosylation Renal Water Absorption Histone H3-K9 Dimethylation Positive Regulation Of Saliva Secretion Carbon Dioxide Transport Epithelial Fluid Transport Meiotic Nuclear Division Protein Localization To Chromosome, Telomeric Region Purine Ribonucleoside Diphosphate Catabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Renal Water Transport Cellular Response To Copper Ion Nucleobase-containing Small Molecule Catabolic Process Pancreatic Juice Secretion Telomere Assembly Proximal Tubule Development Regulation Of Saliva Secretion Cellular Metabolic Process Ribonucleoside Diphosphate Catabolic Process Metanephric Loop Of Henle Development Cerebrospinal Fluid Secretion
Tagcloud ?		a7 circular dichroism dim g12 g13 g9a h3k9 h3k9me0 h3k9me1 h3k9me2 h3k9me3 introduce introduces k14 labrador n324k pkmts prefers processive r8 readout recognizes renders retrievers s10 t11 t6	57r arrests aurora axoneme centriolar centrioles cilia ciliary ciliogenesis crl3 crl3s cul3 developments doublet exit extension initiate instructive k50 ligases mother multistep organelles organize polyubiquitylates removes stepped trichoplein ubiquitylatable
Tagcloud (Difference) ?		a7 circular dichroism dim g12 g13 g9a h3k9 h3k9me0 h3k9me1 h3k9me2 h3k9me3 introduce introduces k14 labrador n324k pkmts prefers processive r8 readout recognizes renders retrievers s10 t11 t6	57r arrests aurora axoneme centriolar centrioles cilia ciliary ciliogenesis crl3 crl3s cul3 developments doublet exit extension initiate instructive k50 ligases mother multistep organelles organize polyubiquitylates removes stepped trichoplein ubiquitylatable
Tagcloud (Intersection) ?