SUV39H2 and PHF19

Number of citations of the paper that reports this interaction (PubMedID 23455924)
0

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		SUV39H2	PHF19
Description		SUV39H2 histone lysine methyltransferase	PHD finger protein 19
Image
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome	Nucleus Nucleoplasm ESC/E(Z) Complex
	Molecular Function	Transcription Cis-regulatory Region Binding Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Histone Methyltransferase Activity Metal Ion Binding Histone H3K9 Methyltransferase Activity Histone H3 Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity S-adenosyl-L-methionine Binding Ubiquitin-like Ligase-substrate Adaptor Activity	DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Metal Ion Binding Histone H3K4me3 Reader Activity Histone H3K36me3 Reader Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Chromatin Remodeling Circadian Rhythm Cell Differentiation Methylation Epigenetic Programming In The Zygotic Pronuclei Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of DNA-templated Transcription Rhythmic Process Cellular Response To Hypoxia	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Stem Cell Population Maintenance Epigenetic Regulation Of Gene Expression Negative Regulation Of Gene Expression, Epigenetic Stem Cell Differentiation
Pathways		PKMTs methylate histone lysines	PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Birth weight ( 27680694 31043758) Corneal astigmatism ( 29422769) High density lipoprotein cholesterol levels ( 29403010) Prostate-specific antigen levels ( 28139693) Pulse pressure ( 27618448 28135244) Refractive error ( 32231278)
Interacting Genes		43 interacting genes: AKAP9 APPL2 AR BLZF1 C8orf74 CBX7 CDCA4 CEP70 CFAP100 CGGBP1 EWSR1 FAM20C GOLGA6L9 GSTCD H3C1 ID2 KCTD17 KLF3 KLHDC4 LCA5L LNX1 LRIF1 MAGEA11 MCM3AP MRFAP1 MTF2 MYL12A NME4 ODAD3 PHF19 PNMA1 POLR3F RAB3IP RASSF1 SHC1 SMAD5 SNF8 UBE2V2 VHL WIZ ZNF212 ZNF557 ZNF57	22 interacting genes: BAG4 BTRC CSNK2A1 DVL3 H3C1 HOMEZ HOXB5 INO80E KDM1A LZTS2 PICK1 POTEB3 RCOR3 SNIP1 SUV39H1 SUV39H2 THAP1 THAP7 TSPYL2 YTHDC1 ZNF837 ZRANB1
Entrez ID		79723	26147
HPRD ID		07580	17846
Ensembl ID		ENSG00000152455	ENSG00000119403
Uniprot IDs		Q9H5I1	A0A087X169 B7Z887 B7Z8H3 F5H8K3 Q5T6S3
PDB IDs		2R3A 6P0R	2E5Q 4BD3 6NQ3 6WAU
Enriched GO Terms of Interacting Partners?		Nucleoplasm Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Histone H3K36me3 Reader Activity Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Biosynthetic Process Chromatin Organization Histone H3K9 Trimethyltransferase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway Epigenetic Regulation Of Gene Expression Negative Regulation Of Macromolecule Metabolic Process Chromatin Negative Regulation Of Metabolic Process Nucleus Histone H3K9 Methyltransferase Activity Epigenetic Programming In The Zygotic Pronuclei Regulation Of DNA Repair Negative Regulation Of Macromolecule Biosynthetic Process Rhythmic Process Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle Negative Regulation Of RNA Metabolic Process Regulation Of DNA Metabolic Process Histone H3 Methyltransferase Activity Cellular Component Assembly Regulation Of Wnt Signaling Pathway Cellular Response To Decreased Oxygen Levels Epigenetic Programming Of Gene Expression Histone Methyltransferase Activity Negative Regulation Of Cell Cycle Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Response To Oxygen Levels Negative Regulation Of MRNA Modification Primary Ureteric Bud Growth Regulation Of Protein Stability Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Signal Transduction By P53 Class Mediator Chromosome Cellular Response To Glucose Starvation Regulation Of Cell Communication Regulation Of Signaling
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?