FAM161A and CARD9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAM161A	CARD9
Gene Name		family with sequence similarity 161, member A	caspase recruitment domain family, member 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Photoreceptor Connecting Cilium Ciliary Basal Body	Cytoplasm
	Molecular Function	Protein Binding	Protein Homodimerization Activity CARD Domain Binding
	Biological Process	Visual Perception Cilium Assembly Response To Stimulus	Response To Fungus Response To Peptidoglycan Response To Muramyl Dipeptide Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Stress-activated MAPK Cascade Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Drug Regulation Of Tumor Necrosis Factor Biosynthetic Process Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Exogenous DsRNA Regulation Of Interleukin-2 Biosynthetic Process Innate Immune Response Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of JNK Cascade Defense Response To Gram-positive Bacterium Defense Response To Virus Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Pathways			Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways NOD1/2 Signaling Pathway Innate Immune System
Drugs
Diseases
GWAS			Ankylosing spondylitis ( 21743469) Crohn's disease ( 22936669 21102463) Inflammatory bowel disease ( 23128233) Monocyte chemoattractant protein-1 ( 23017229) Obesity-related traits ( 23251661) Ulcerative colitis ( 19915572 20228799 21297633)
Protein-Protein Interactions		63 interactors: BEND3 BEND5 BRCA1 CADPS CALCOCO1 CALCOCO2 CARD9 CCDC102B CCDC136 CCDC155 CCDC33 CCDC57 CDR2 CEP44 CEP57L1 CEP63 CEP70 DHX32 DOCK8 EHMT2 FAM9B FSD2 HMBOX1 IKZF1 KIAA0753 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LZTS2 MCM6 MDFI MID2 MIPOL1 MTUS2 NECAB2 NINL NUTM1 PDE4DIP PHC2 PNMA2 POC5 PPFIA1 PPM1F RINT1 RUNDC3A SPERT SSX2IP STX11 SYCE1 TFIP11 TMCC2 TNIP1 TRAF1 TRIM15 TRIM37 TRIM54 TSGA10 TXLNB ZBTB1 ZBTB14 ZBTB43 ZBTB8A	65 interactors: ABLIM1 AES ALS2CR11 AMOTL2 BCL10 BLZF1 C1orf94 CCDC36 CCDC85B CCHCR1 CDCA7L CEP57L1 CEP70 CSNK2A1 CWF19L2 DAXX DUSP13 EIF4E2 FAM124B FAM161A FAM208B FAM50B HMBOX1 IQCE KCTD9 KIAA0408 KIF9 KRT19 KRT31 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 LENG1 LMO1 LZTS2 MEOX2 MFAP1 NECAB2 PAK7 PBX2 PHC2 PNMA5 PPP1R18 RTP5 SSX2IP STX11 SUMO1 TCEANC TCL1A TFIP11 TNFAIP1 TRIM23 TRIM29 TRIM42 TRIM54 TSNAX USP15 VPS28 ZCCHC7 ZNF250 ZNF417 ZNF572 ZNF587 ZNF655
Entrez ID		84140	64170
HPRD ID		18996	06236
Ensembl ID		ENSG00000170264	ENSG00000187796
Uniprot IDs		Q3B820	Q9H257
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Negative Regulation Of RNA Biosynthetic Process Organelle Organization Negative Regulation Of Centriole Replication Cell Cycle Process Negative Regulation Of Gene Expression Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Synapsis Homologous Chromosome Segregation Negative Regulation Of Cytoskeleton Organization Regulation Of Centriole Replication Leukocyte Cell-cell Adhesion Cellular Component Assembly Negative Regulation Of Viral Process Negative Regulation Of Viral Release From Host Cell Meiotic Chromosome Segregation Negative Regulation Of Centrosome Duplication Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of RNA Biosynthetic Process Centrosome Organization Chromosome Segregation Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Viral Release From Host Cell Regulation Of Nitrogen Compound Metabolic Process Synaptonemal Complex Assembly Microtubule Cytoskeleton Organization Meiosis I Microtubule Organizing Center Organization Synaptonemal Complex Organization Neurotransmitter Secretion Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Chromosome Organization Regulation Of Cytoskeleton Organization Microtubule-based Process Regulation Of Neurotransmitter Levels Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation	Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Organelle Organization Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Developmental Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Wnt Signaling Pathway Spliceosomal Complex Disassembly Organelle Assembly Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Mast Cell Cytokine Production Histone H2B Conserved C-terminal Lysine Deubiquitination Lymphotoxin A Biosynthetic Process Interleukin-6 Biosynthetic Process Negative Regulation Of Biosynthetic Process
Tagcloud ?			adapter assembly danger defense discuss engaged framework fungal homeostasis inducible innate lectin links lymphoid lymphoma malt mucosa multifunctional nonredundant oligomerization paracaspase polymorphisms responds rig rlrs sensors spleen syk
Tagcloud (Difference) ?			adapter assembly danger defense discuss engaged framework fungal homeostasis inducible innate lectin links lymphoid lymphoma malt mucosa multifunctional nonredundant oligomerization paracaspase polymorphisms responds rig rlrs sensors spleen syk
Tagcloud (Intersection) ?