FAM161A and CEP72

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAM161A	CEP72
Description		FAM161 centrosomal protein A	centrosomal protein 72
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Astral Microtubule Photoreceptor Inner Segment Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Centriole Cytosol Cytoskeleton Spindle Microtubule Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection Mitotic Spindle Mitotic Spindle Pole	Cytoplasm Centrosome Cytosol Cytoskeleton Centriolar Satellite Ciliary Basal Body
	Molecular Function	Protein Binding Microtubule Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Visual Perception Cell Projection Organization Cilium Organization Cilium Assembly	Spindle Organization Centriole Replication Gamma-tubulin Complex Localization Regulation Of Protein Localization To Centrosome
Pathways			Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Atrial fibrillation ( 29892015) Erectile dysfunction ( 30583798) Systemic lupus erythematosus ( 28714469)	Barrett's esophagus or Esophageal adenocarcinoma ( 27527254 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Esophageal adenocarcinoma ( 27527254) Lung disease severity in cystic fibrosis ( 26417704) Obesity-related traits ( 23251661) Ulcerative colitis ( 20228799 28067908) Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia ( 25710658)
Interacting Genes		139 interacting genes: AQP1 AXIN2 BACH2 BEGAIN BEND3 BEND5 BICD2 BRCA1 CADPS CALCOCO1 CALCOCO2 CARD9 CBY2 CCDC102B CCDC125 CCDC13 CCDC136 CCDC185 CCDC33 CCDC57 CCDC88B CCNC CCNDBP1 CDR2 CDR2L CEP44 CEP57L1 CEP63 CEP70 CEP72 CTNNA3 DHX32 DOCK8 DRC4 DVL2 EHMT2 EVI5 FAM9B FSD2 FXR1 GOLGA2 GOLGA6L9 GPBP1 GPRASP3 GRIPAP1 HEXIM2 HMBOX1 HOOK1 HOOK2 IKZF1 INO80E JRK KANK2 KASH5 KAT5 KDM1A KIAA0753 KIAA1328 KIFC3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP5-7 KRTAP5-9 LDOC1 LMNA LURAP1L LZTS1 LZTS2 MAGEA11 MCC MCM6 MDFI MID2 MIPOL1 MKRN1 MTCL2 MTUS2 NECAB2 NINL NUTM1 OSBPL3 PDE4DIP PHC2 PIBF1 PICK1 PLEKHG4 PNMA1 PNMA2 POC5 PPFIA1 PPM1F PPP2R3C PRKAR1B QARS1 RINT1 ROPN1 RUBCN RUNDC3A SCNM1 SMARCD1 SSX2IP STX11 SYCE1 TAX1BP1 TBC1D1 TFIP11 TMCC2 TNIP1 TNIP3 TRAF1 TRAF2 TRIB3 TRIM15 TRIM27 TRIM37 TRIM41 TRIM54 TRIM69 TSGA10 TXLNB VIM VPS52 ZBTB1 ZBTB14 ZBTB43 ZBTB8A ZIM2 ZNF24 ZNF250 ZNF276 ZNF426 ZNF526 ZNF792 ZRANB1 ZSCAN12	26 interacting genes: ATXN7 CATIP CHCHD3 FAM161A FAM90A1 FXR1 GOLGA6L9 IGHM IL16 INCA1 KIAA0408 LNX1 MCM10 NME7 PCM1 PIN4 PSMA1 SHANK3 SMARCA2 SPATA2 SPATA24 SRSF2 STAMBPL1 ZBTB16 ZNF417 ZNF688
Entrez ID		84140	55722
HPRD ID		18996	07685
Ensembl ID		ENSG00000170264	ENSG00000112877
Uniprot IDs		Q3B820	Q9P209
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Microtubule-based Process Identical Protein Binding Centrosome Microtubule Organizing Center Organization Microtubule Cytoskeleton Organization Cytoskeleton Intermediate Filament Centriole Replication Cytoplasm Centrosome Cycle Centriole Assembly Cytoskeleton Organization Microtubule Binding Cytoplasmic Microtubule Organization Response To Muramyl Dipeptide Microtubule Organelle Organization Negative Regulation Of RNA Metabolic Process Cellular Response To Muramyl Dipeptide Dynein Light Intermediate Chain Binding Zinc Ion Binding Regulation Of Organelle Organization Membraneless Organelle Assembly Negative Regulation Of Nucleobase-containing Compound Metabolic Process Centriolar Satellite Keratin Filament Cytosol Microtubule Organizing Center Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Organelle Assembly Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Suppression Of Viral Release By Host Centriole Negative Regulation Of Fatty Acid Biosynthetic Process Transcription Coactivator Activity Nuclear Pore Localization FHF Complex Ubiquitin Protein Ligase Activity Protein Localization To Cytoskeleton Nucleus
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