FAM161A and PPM1F

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)

		FAM161A	PPM1F
Gene Name		family with sequence similarity 161, member A	protein phosphatase, Mg2+/Mn2+ dependent, 1F
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Photoreceptor Connecting Cilium Ciliary Basal Body	Cytosol Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Serine/threonine Phosphatase Activity Protein Binding Phosphatase Activity Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding
	Biological Process	Visual Perception Cilium Assembly Response To Stimulus	Negative Regulation Of Protein Kinase Activity Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Histone Dephosphorylation Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Response To Drug Peptidyl-threonine Dephosphorylation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Growth Positive Regulation Of Chemotaxis Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		63 interactors: BEND3 BEND5 BRCA1 CADPS CALCOCO1 CALCOCO2 CARD9 CCDC102B CCDC136 CCDC155 CCDC33 CCDC57 CDR2 CEP44 CEP57L1 CEP63 CEP70 DHX32 DOCK8 EHMT2 FAM9B FSD2 HMBOX1 IKZF1 KIAA0753 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LZTS2 MCM6 MDFI MID2 MIPOL1 MTUS2 NECAB2 NINL NUTM1 PDE4DIP PHC2 PNMA2 POC5 PPFIA1 PPM1F RINT1 RUNDC3A SPERT SSX2IP STX11 SYCE1 TFIP11 TMCC2 TNIP1 TRAF1 TRIM15 TRIM37 TRIM54 TSGA10 TXLNB ZBTB1 ZBTB14 ZBTB43 ZBTB8A	8 interactors: ARHGEF7 CAMK2A CAMK2G FAM161A FEM1A FEM1B MARS PAK1
Entrez ID		84140	9647
HPRD ID		18996	10163
Ensembl ID		ENSG00000170264	ENSG00000100034
Uniprot IDs		Q3B820	B7Z2C3 P49593
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Negative Regulation Of RNA Biosynthetic Process Organelle Organization Negative Regulation Of Centriole Replication Cell Cycle Process Negative Regulation Of Gene Expression Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Synapsis Homologous Chromosome Segregation Negative Regulation Of Cytoskeleton Organization Regulation Of Centriole Replication Leukocyte Cell-cell Adhesion Cellular Component Assembly Negative Regulation Of Viral Process Negative Regulation Of Viral Release From Host Cell Meiotic Chromosome Segregation Negative Regulation Of Centrosome Duplication Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of RNA Biosynthetic Process Centrosome Organization Chromosome Segregation Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Viral Release From Host Cell Regulation Of Nitrogen Compound Metabolic Process Synaptonemal Complex Assembly Microtubule Cytoskeleton Organization Meiosis I Microtubule Organizing Center Organization Synaptonemal Complex Organization Neurotransmitter Secretion Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Chromosome Organization Regulation Of Cytoskeleton Organization Microtubule-based Process Regulation Of Neurotransmitter Levels Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation	Protein Autophosphorylation Regulation Of Cellular Response To Heat Apoptotic Process Programmed Cell Death Cellular Response To Heat Cell Death Death Regulation Of Ubiquitin-protein Transferase Activity Ephrin Receptor Signaling Pathway Response To Heat Methionyl-tRNA Aminoacylation Cellular Protein Metabolic Process Interferon-gamma-mediated Signaling Pathway Positive Regulation Of Lamellipodium Morphogenesis Cellular Response To Interferon-gamma G1/S Transition Of Mitotic Cell Cycle Response To Interferon-gamma Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Epithelial Cell Maturation Involved In Prostate Gland Development Response To Temperature Stimulus Regulation Of Calcium Ion Transport Cellular Protein Modification Process Innate Immune Response Regulation Of Protein Ubiquitination Cellular Response To Organic Substance Cell Projection Morphogenesis Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Lamellipodium Morphogenesis Regulation Of Relaxation Of Cardiac Muscle Histone H3-T11 Phosphorylation Cell Part Morphogenesis Morphogenesis Of A Branching Epithelium Regulation Of Relaxation Of Muscle Protein Metabolic Process Morphogenesis Of A Branching Structure Regulation Of Skeletal Muscle Adaptation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Immune System Process Contact Inhibition Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Fibroblast Migration Cell Projection Assembly Regulation Of DNA Damage Checkpoint Cell Morphogenesis Response To Abiotic Stimulus Calcium Ion Transport Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Catalytic Activity Cell Projection Organization
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