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CARD9 and FAM124B
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CARD9
FAM124B
Gene Name
caspase recruitment domain family, member 9
family with sequence similarity 124B
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Molecular Function
Protein Homodimerization Activity
CARD Domain Binding
Protein Binding
Biological Process
Response To Fungus
Response To Peptidoglycan
Response To Muramyl Dipeptide
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Response To Drug
Regulation Of Tumor Necrosis Factor Biosynthetic Process
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Exogenous DsRNA
Regulation Of Interleukin-2 Biosynthetic Process
Innate Immune Response
Regulation Of Interleukin-6 Biosynthetic Process
Positive Regulation Of JNK Cascade
Defense Response To Gram-positive Bacterium
Defense Response To Virus
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Pathways
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
NOD1/2 Signaling Pathway
Innate Immune System
Drugs
Diseases
GWAS
Ankylosing spondylitis (
21743469
)
Crohn's disease (
22936669
21102463
)
Inflammatory bowel disease (
23128233
)
Monocyte chemoattractant protein-1 (
23017229
)
Obesity-related traits (
23251661
)
Ulcerative colitis (
19915572
20228799
21297633
)
Protein-Protein Interactions
65 interactors:
ABLIM1
AES
ALS2CR11
AMOTL2
BCL10
BLZF1
C1orf94
CCDC36
CCDC85B
CCHCR1
CDCA7L
CEP57L1
CEP70
CSNK2A1
CWF19L2
DAXX
DUSP13
EIF4E2
FAM124B
FAM161A
FAM208B
FAM50B
HMBOX1
IQCE
KCTD9
KIAA0408
KIF9
KRT19
KRT31
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-5
LENG1
LMO1
LZTS2
MEOX2
MFAP1
NECAB2
PAK7
PBX2
PHC2
PNMA5
PPP1R18
RTP5
SSX2IP
STX11
SUMO1
TCEANC
TCL1A
TFIP11
TNFAIP1
TRIM23
TRIM29
TRIM42
TRIM54
TSNAX
USP15
VPS28
ZCCHC7
ZNF250
ZNF417
ZNF572
ZNF587
ZNF655
29 interactors:
ADAMTSL4
AES
BIRC7
CARD9
CCDC85B
EFEMP2
GOLGA2
KCTD6
KCTD9
KIAA1958
KRT19
KRT31
KRT40
KRTAP10-3
KRTAP10-7
KRTAP10-9
KRTAP5-9
LZTS2
MDFI
MKRN3
NOTCH2NL
RBPMS
RINT1
SSX2IP
TCF4
TRIM37
TRIM54
TRIP6
USHBP1
Entrez ID
64170
79843
HPRD ID
06236
08663
Ensembl ID
ENSG00000187796
ENSG00000124019
Uniprot IDs
Q9H257
Q9H5Z6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Gene Expression
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Organelle Organization
Regulation Of Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Developmental Process
Regulation Of Cellular Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Wnt Signaling Pathway
Spliceosomal Complex Disassembly
Organelle Assembly
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Gene Expression
Positive Regulation Of Mast Cell Cytokine Production
Histone H2B Conserved C-terminal Lysine Deubiquitination
Lymphotoxin A Biosynthetic Process
Interleukin-6 Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Wnt Signaling Pathway
Regulation Of Protein Localization To Nucleus
Regulation Of Nucleocytoplasmic Transport
Regulation Of Intracellular Transport
Regulation Of Binding
Regulation Of Intracellular Protein Transport
Negative Regulation Of Binding
Regulation Of Signal Transduction
Positive Regulation Of Nucleocytoplasmic Transport
Regulation Of Wnt Signaling Pathway
Positive Regulation Of JNK Cascade
Cellular Component Assembly
Regulation Of Signaling
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of Cellular Localization
Negative Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Protein Binding
Cell Differentiation Involved In Embryonic Placenta Development
Positive Regulation Of Intracellular Protein Transport
Regulation Of JNK Cascade
Activation Of JUN Kinase Activity
Regulation Of Protein Import Into Nucleus
Regulation Of Stress-activated MAPK Cascade
Regulation Of Protein Localization
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Signal Transduction
Regulation Of Natural Killer Cell Apoptotic Process
Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint
Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Protein Binding
Positive Regulation Of Intracellular Transport
Negative Regulation Of Fat Cell Differentiation
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of JUN Kinase Activity
Wnt Signaling Pathway
Regulation Of Protein Transport
Negative Regulation Of Protein Localization To Nucleus
Regulation Of JUN Kinase Activity
Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process
Histone H2A-K119 Monoubiquitination
JNK Cascade
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of Transcription Factor Import Into Nucleus
Regulation Of Establishment Of Protein Localization
Negative Regulation Of RNA Biosynthetic Process
Maintenance Of DNA Repeat Elements
Tagcloud
?
adapter
assembly
danger
defense
discuss
engaged
framework
fungal
homeostasis
inducible
innate
lectin
links
lymphoid
lymphoma
malt
mucosa
multifunctional
nonredundant
oligomerization
paracaspase
polymorphisms
responds
rig
rlrs
sensors
spleen
syk
Tagcloud (Difference)
?
adapter
assembly
danger
defense
discuss
engaged
framework
fungal
homeostasis
inducible
innate
lectin
links
lymphoid
lymphoma
malt
mucosa
multifunctional
nonredundant
oligomerization
paracaspase
polymorphisms
responds
rig
rlrs
sensors
spleen
syk
Tagcloud (Intersection)
?