FAM161A and MCM6

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAM161A	MCM6
Gene Name		family with sequence similarity 161, member A	minichromosome maintenance complex component 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Photoreceptor Connecting Cilium Ciliary Basal Body	Nucleus Nucleoplasm MCM Complex
	Molecular Function	Protein Binding	Single-stranded DNA Binding ATP-dependent DNA Helicase Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Visual Perception Cilium Assembly Response To Stimulus	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Replication DNA Unwinding Involved In DNA Replication DNA Replication Initiation DNA Strand Elongation Involved In DNA Replication
Pathways			Synthesis of DNA G2/M Checkpoints Activation of the pre-replicative complex DNA Replication Pre-Initiation M/G1 Transition Regulation of DNA replication Activation of the pre-replicative complex Orc1 removal from chromatin S Phase DNA strand elongation Cell Cycle, Mitotic Assembly of the pre-replicative complex Orc1 removal from chromatin G1/S Transition Activation of ATR in response to replication stress Cell Cycle Checkpoints Removal of licensing factors from origins Mitotic G1-G1/S phases Switching of origins to a post-replicative state Unwinding of DNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		63 interactors: BEND3 BEND5 BRCA1 CADPS CALCOCO1 CALCOCO2 CARD9 CCDC102B CCDC136 CCDC155 CCDC33 CCDC57 CDR2 CEP44 CEP57L1 CEP63 CEP70 DHX32 DOCK8 EHMT2 FAM9B FSD2 HMBOX1 IKZF1 KIAA0753 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LZTS2 MCM6 MDFI MID2 MIPOL1 MTUS2 NECAB2 NINL NUTM1 PDE4DIP PHC2 PNMA2 POC5 PPFIA1 PPM1F RINT1 RUNDC3A SPERT SSX2IP STX11 SYCE1 TFIP11 TMCC2 TNIP1 TRAF1 TRIM15 TRIM37 TRIM54 TSGA10 TXLNB ZBTB1 ZBTB14 ZBTB43 ZBTB8A	31 interactors: ALS2CR11 CCNA1 CDC45 CDC7 CDKN2A CDT1 CRLS1 DBF4 FAM161A GMNN HDAC1 IL36RN ING5 MCM10 MCM2 MCM3 MCM4 MCM7 MCM8 MLLT3 NUDT2 ORC1 ORC2 ORC4 ORC6 PSMA1 RPA1 SCNM1 SMC1A SNRPB2 ZBTB9
Entrez ID		84140	4175
HPRD ID		18996	03485
Ensembl ID		ENSG00000170264	ENSG00000076003
Uniprot IDs		Q3B820	Q14566
PDB IDs			2KLQ 2LE8
Enriched GO Terms of Interacting Partners?		Cell Cycle Negative Regulation Of RNA Biosynthetic Process Organelle Organization Negative Regulation Of Centriole Replication Cell Cycle Process Negative Regulation Of Gene Expression Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Synapsis Homologous Chromosome Segregation Negative Regulation Of Cytoskeleton Organization Regulation Of Centriole Replication Leukocyte Cell-cell Adhesion Cellular Component Assembly Negative Regulation Of Viral Process Negative Regulation Of Viral Release From Host Cell Meiotic Chromosome Segregation Negative Regulation Of Centrosome Duplication Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of RNA Biosynthetic Process Centrosome Organization Chromosome Segregation Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Viral Release From Host Cell Regulation Of Nitrogen Compound Metabolic Process Synaptonemal Complex Assembly Microtubule Cytoskeleton Organization Meiosis I Microtubule Organizing Center Organization Synaptonemal Complex Organization Neurotransmitter Secretion Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Chromosome Organization Regulation Of Cytoskeleton Organization Microtubule-based Process Regulation Of Neurotransmitter Levels Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation	G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle DNA Replication Mitotic Cell Cycle Process DNA-dependent DNA Replication DNA Replication Initiation Cell Cycle Cell Cycle Process DNA Metabolic Process DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle DNA Duplex Unwinding DNA Geometric Change DNA Unwinding Involved In DNA Replication Chromosome Organization Cellular Metabolic Process DNA Conformation Change Regulation Of Cell Cycle Double-strand Break Repair Via Break-induced Replication Regulation Of Cell Cycle Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cellular Response To DNA Damage Stimulus Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Regulation Of DNA Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Double-strand Break Repair Cellular Response To Stress Regulation Of Nuclear Cell Cycle DNA Replication DNA Replication Checkpoint Cellular Process Positive Regulation Of Cell Cycle Process Cell Cycle Checkpoint DNA Recombination Organelle Organization Negative Regulation Of Cell Cycle
Tagcloud ?			benign bronchial brushing brushings clinicopathologic considerable consisting cytology detecting icbp90 immunocytochemistry inpatients ki67 kiaa0317 kiaa1522 ligase lung mcm7 minichromosome nonsmall nsclc outpatients panel sclc specimens tp53 tp63 uhr1 uncharacterized
Tagcloud (Difference) ?			benign bronchial brushing brushings clinicopathologic considerable consisting cytology detecting icbp90 immunocytochemistry inpatients ki67 kiaa0317 kiaa1522 ligase lung mcm7 minichromosome nonsmall nsclc outpatients panel sclc specimens tp53 tp63 uhr1 uncharacterized
Tagcloud (Intersection) ?