CARD9 and MFAP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CARD9	MFAP1
Gene Name		caspase recruitment domain family, member 9	microfibrillar-associated protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Microfibril Extracellular Region
	Molecular Function	Protein Homodimerization Activity CARD Domain Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Response To Fungus Response To Peptidoglycan Response To Muramyl Dipeptide Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Stress-activated MAPK Cascade Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Drug Regulation Of Tumor Necrosis Factor Biosynthetic Process Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Exogenous DsRNA Regulation Of Interleukin-2 Biosynthetic Process Innate Immune Response Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of JNK Cascade Defense Response To Gram-positive Bacterium Defense Response To Virus Nucleotide-binding Oligomerization Domain Containing Signaling Pathway	Biological_process Extracellular Matrix Organization
Pathways		Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways NOD1/2 Signaling Pathway Innate Immune System	Molecules associated with elastic fibres Elastic fibre formation
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 21743469) Crohn's disease ( 22936669 21102463) Inflammatory bowel disease ( 23128233) Monocyte chemoattractant protein-1 ( 23017229) Obesity-related traits ( 23251661) Ulcerative colitis ( 19915572 20228799 21297633)
Protein-Protein Interactions		65 interactors: ABLIM1 AES ALS2CR11 AMOTL2 BCL10 BLZF1 C1orf94 CCDC36 CCDC85B CCHCR1 CDCA7L CEP57L1 CEP70 CSNK2A1 CWF19L2 DAXX DUSP13 EIF4E2 FAM124B FAM161A FAM208B FAM50B HMBOX1 IQCE KCTD9 KIAA0408 KIF9 KRT19 KRT31 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 LENG1 LMO1 LZTS2 MEOX2 MFAP1 NECAB2 PAK7 PBX2 PHC2 PNMA5 PPP1R18 RTP5 SSX2IP STX11 SUMO1 TCEANC TCL1A TFIP11 TNFAIP1 TRIM23 TRIM29 TRIM42 TRIM54 TSNAX USP15 VPS28 ZCCHC7 ZNF250 ZNF417 ZNF572 ZNF587 ZNF655	47 interactors: AES AMOTL2 BEND7 CARD9 CCDC57 CDCA7L CEP55 CEP57L1 CEP70 COIL CSNK2A1 DHX38 DHX8 FAM9B FRA10AC1 FXR2 GKAP1 GOLGA2 HMBOX1 HSPB1 IK KATNBL1 KIFC3 KRT40 LDOC1 MAD1L1 MID2 MIPOL1 MTUS2 NDC80 PHC2 SART1 SMU1 SNIP1 SNW1 SSX2IP STX11 TADA2A TRIM42 TRIM54 U2AF1 VPS52 YWHAG ZBTB14 ZBTB8A ZFP64 ZNF398
Entrez ID		64170	4236
HPRD ID		06236	02569
Ensembl ID		ENSG00000187796	ENSG00000140259
Uniprot IDs		Q9H257	P55081
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Organelle Organization Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Developmental Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Wnt Signaling Pathway Spliceosomal Complex Disassembly Organelle Assembly Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Mast Cell Cytokine Production Histone H2B Conserved C-terminal Lysine Deubiquitination Lymphotoxin A Biosynthetic Process Interleukin-6 Biosynthetic Process Negative Regulation Of Biosynthetic Process	Mitotic Cell Cycle Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Mitotic Cell Cycle Process Transcription, DNA-templated RNA Biosynthetic Process Cell Cycle Process Cell Cycle RNA Splicing RNA Processing Regulation Of Chromosome Organization Regulation Of Tumor Necrosis Factor Biosynthetic Process MRNA Processing Negative Regulation Of Cellular Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Metabolic Process Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Splicing Termination Of RNA Polymerase II Transcription Maturation Of 5S RRNA Regulation Of Metaphase Plate Congression Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Organelle Organization Regulation Of Mitotic Metaphase/anaphase Transition Microtubule Anchoring Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Gene Expression Positive Regulation Of Cytotoxic T Cell Differentiation Positive Regulation Of Vitamin D Receptor Signaling Pathway Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Binding Positive Regulation Of Tumor Necrosis Factor Production Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Cellular Macromolecule Biosynthetic Process Posttranscriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Zonula Adherens Maintenance Microtubule-based Process MRNA Export From Nucleus Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Tagcloud ?		adapter assembly danger defense discuss engaged framework fungal homeostasis inducible innate lectin links lymphoid lymphoma malt mucosa multifunctional nonredundant oligomerization paracaspase polymorphisms responds rig rlrs sensors spleen syk
Tagcloud (Difference) ?		adapter assembly danger defense discuss engaged framework fungal homeostasis inducible innate lectin links lymphoid lymphoma malt mucosa multifunctional nonredundant oligomerization paracaspase polymorphisms responds rig rlrs sensors spleen syk
Tagcloud (Intersection) ?