FAM161A and IKZF1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FAM161A	IKZF1
Gene Name		family with sequence similarity 161, member A	IKAROS family zinc finger 1 (Ikaros)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Photoreceptor Connecting Cilium Ciliary Basal Body	Nucleus Pericentric Heterochromatin Cytoplasm Protein Complex
	Molecular Function	Protein Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Visual Perception Cilium Assembly Response To Stimulus	Negative Regulation Of Transcription From RNA Polymerase II Promoter Natural Killer Cell Differentiation Transcription, DNA-templated Cell Cycle Mesoderm Development Chromatin Modification B Cell Differentiation T Cell Differentiation Forebrain Development Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Lymph Node Development Thymus Development Peyer's Patch Development Positive Regulation Of NK T Cell Differentiation Retina Development In Camera-type Eye
Pathways
Drugs
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 23512250 19684603 19684604) Crohn's disease ( 21102463) Hippocampal atrophy ( 19668339) IgG glycosylation ( 23382691) Inflammatory bowel disease ( 23128233) Mean corpuscular volume ( 19862010) Red blood cell traits ( 23222517) Systemic lupus erythematosus ( 23273568 19838193)
Protein-Protein Interactions		63 interactors: BEND3 BEND5 BRCA1 CADPS CALCOCO1 CALCOCO2 CARD9 CCDC102B CCDC136 CCDC155 CCDC33 CCDC57 CDR2 CEP44 CEP57L1 CEP63 CEP70 DHX32 DOCK8 EHMT2 FAM9B FSD2 HMBOX1 IKZF1 KIAA0753 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 LZTS2 MCM6 MDFI MID2 MIPOL1 MTUS2 NECAB2 NINL NUTM1 PDE4DIP PHC2 PNMA2 POC5 PPFIA1 PPM1F RINT1 RUNDC3A SPERT SSX2IP STX11 SYCE1 TFIP11 TMCC2 TNIP1 TRAF1 TRIM15 TRIM37 TRIM54 TSGA10 TXLNB ZBTB1 ZBTB14 ZBTB43 ZBTB8A	75 interactors: AEN ALKBH3 ANKRD11 AP1M1 AP2M1 ARMC7 BYSL C19orf66 C1orf109 C1orf174 C8orf33 CBX8 CDK2AP2 CEP57L1 CHD3 CKS1B CSNK1G1 CTBP1 CTBP2 DCX DDX6 DYRK2 FAM161A FAM214B FAM50B FAM74A4 FGF12 FRMD6 GLRX3 GMCL1P1 GTF2B HDAC1 HDAC2 IKZF2 IKZF3 IKZF4 IKZF5 ISCU KIF9 LMO3 LSM4 MAD2L2 MCRS1 MORF4L1 MORF4L2 MTA1 NEK6 NOC4L NUDT21 PIN1 PNKP PRKAB2 PSMA1 PSMA4 RAD51D RBBP8 RWDD2B SAP18 SCNM1 SDCBP SH2D4A SIN3A SIN3B SMARCA4 SNRPF SNW1 SPATC1L SYT17 TBP TDG UBE2I WTAP ZMAT2 ZNF417 ZNF581
Entrez ID		84140	10320
HPRD ID		18996	04318
Ensembl ID		ENSG00000170264	ENSG00000185811
Uniprot IDs		Q3B820	Q13422
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Negative Regulation Of RNA Biosynthetic Process Organelle Organization Negative Regulation Of Centriole Replication Cell Cycle Process Negative Regulation Of Gene Expression Positive Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Synapsis Homologous Chromosome Segregation Negative Regulation Of Cytoskeleton Organization Regulation Of Centriole Replication Leukocyte Cell-cell Adhesion Cellular Component Assembly Negative Regulation Of Viral Process Negative Regulation Of Viral Release From Host Cell Meiotic Chromosome Segregation Negative Regulation Of Centrosome Duplication Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of RNA Biosynthetic Process Centrosome Organization Chromosome Segregation Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Viral Release From Host Cell Regulation Of Nitrogen Compound Metabolic Process Synaptonemal Complex Assembly Microtubule Cytoskeleton Organization Meiosis I Microtubule Organizing Center Organization Synaptonemal Complex Organization Neurotransmitter Secretion Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G2/M Transition Of Mitotic Cell Cycle T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Chromosome Organization Regulation Of Cytoskeleton Organization Microtubule-based Process Regulation Of Neurotransmitter Levels Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Histone H4-K20 Methylation	RNA Metabolic Process Gene Expression Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression, Epigenetic Cellular Response To Stress Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Organelle Organization Chromosome Organization Chromatin Modification Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression, Epigenetic Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Negative Regulation Of Gene Expression Histone Deacetylation Protein Deacetylation Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Histone Modification Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter DNA Repair Regulation Of Cell Cycle Signal Transduction By P53 Class Mediator Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway DNA Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Metabolic Process Regulation Of Cell Cycle Phase Transition RNA Splicing
Tagcloud ?			agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Difference) ?			agree china cnki cochrane databases deletion derive efs eligible embase estimation ethnicity hazard infrastructure intervals lymphoblastic meta methodology precise pubmed random ratios science stratified subgroups unfavorable updated wanfang web
Tagcloud (Intersection) ?