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CARD9 and PPP1R18
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
CARD9
PPP1R18
Gene Name
caspase recruitment domain family, member 9
protein phosphatase 1, regulatory subunit 18
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytoplasm
Cytoskeleton
Molecular Function
Protein Homodimerization Activity
CARD Domain Binding
Actin Binding
Phosphatase Binding
Biological Process
Response To Fungus
Response To Peptidoglycan
Response To Muramyl Dipeptide
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Stress-activated MAPK Cascade
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Response To Drug
Regulation Of Tumor Necrosis Factor Biosynthetic Process
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Exogenous DsRNA
Regulation Of Interleukin-2 Biosynthetic Process
Innate Immune Response
Regulation Of Interleukin-6 Biosynthetic Process
Positive Regulation Of JNK Cascade
Defense Response To Gram-positive Bacterium
Defense Response To Virus
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Pathways
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
NOD1/2 Signaling Pathway
Innate Immune System
Drugs
Diseases
GWAS
Ankylosing spondylitis (
21743469
)
Crohn's disease (
22936669
21102463
)
Inflammatory bowel disease (
23128233
)
Monocyte chemoattractant protein-1 (
23017229
)
Obesity-related traits (
23251661
)
Ulcerative colitis (
19915572
20228799
21297633
)
Protein-Protein Interactions
65 interactors:
ABLIM1
AES
ALS2CR11
AMOTL2
BCL10
BLZF1
C1orf94
CCDC36
CCDC85B
CCHCR1
CDCA7L
CEP57L1
CEP70
CSNK2A1
CWF19L2
DAXX
DUSP13
EIF4E2
FAM124B
FAM161A
FAM208B
FAM50B
HMBOX1
IQCE
KCTD9
KIAA0408
KIF9
KRT19
KRT31
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-5
LENG1
LMO1
LZTS2
MEOX2
MFAP1
NECAB2
PAK7
PBX2
PHC2
PNMA5
PPP1R18
RTP5
SSX2IP
STX11
SUMO1
TCEANC
TCL1A
TFIP11
TNFAIP1
TRIM23
TRIM29
TRIM42
TRIM54
TSNAX
USP15
VPS28
ZCCHC7
ZNF250
ZNF417
ZNF572
ZNF587
ZNF655
37 interactors:
CALCOCO2
CARD9
CCDC102B
CCDC136
CCDC155
CCDC57
DES
FAM9B
FSD2
GOLGA2
HOMER3
KCTD9
KRT13
KRT15
KRT19
KRT31
KRT40
LZTS2
MID2
MTUS2
NEFL
PDE4DIP
PPP1CA
PPP1CC
SPDL1
SPERT
STX11
TCF4
TEX11
TFIP11
TRAF2
TRIM23
TRIM27
TRIM54
TRIM69
TSGA10
VPS52
Entrez ID
64170
170954
HPRD ID
06236
11172
Ensembl ID
ENSG00000187796
ENSG00000146112
Uniprot IDs
Q9H257
Q6NYC8
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Gene Expression
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Organelle Organization
Regulation Of Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Developmental Process
Regulation Of Cellular Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Wnt Signaling Pathway
Spliceosomal Complex Disassembly
Organelle Assembly
Cellular Nitrogen Compound Metabolic Process
Negative Regulation Of Gene Expression
Positive Regulation Of Mast Cell Cytokine Production
Histone H2B Conserved C-terminal Lysine Deubiquitination
Lymphotoxin A Biosynthetic Process
Interleukin-6 Biosynthetic Process
Negative Regulation Of Biosynthetic Process
Cellular Component Assembly
Glycogen Metabolic Process
Cell Cycle
Polysaccharide Metabolic Process
Negative Regulation Of Viral Release From Host Cell
Cytoskeleton Organization
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Triglyceride Catabolic Process
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Negative Regulation Of Viral Transcription
Innate Immune Response
Entrainment Of Circadian Clock By Photoperiod
Regulation Of Viral Release From Host Cell
Photoperiodism
Entrainment Of Circadian Clock
Acylglycerol Catabolic Process
Protein Ubiquitination
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Energy Reserve Metabolic Process
Organelle Organization
Cellular Protein Complex Assembly
Protein Modification By Small Protein Conjugation
Regulation Of Protein Binding
Protein K63-linked Ubiquitination
Cellular Macromolecular Complex Assembly
Protein Trimerization
Establishment Of Chromosome Localization
Protein Complex Assembly
Embryonic Digestive Tract Development
Spliceosomal Complex Disassembly
Chromosome Localization To Nuclear Envelope Involved In Synapsis
Regulation Of Cellular Response To Growth Factor Stimulus
Organelle Localization
Cellular Localization
Cell Division
Regulation Of Extrinsic Apoptotic Signaling Pathway
Establishment Of Localization In Cell
Synapsis
Response To Organic Substance
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Homologous Chromosome Segregation
Single Organism Reproductive Process
Chromosome Segregation
Negative Regulation Of Interleukin-2 Secretion
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Embryonic Ectodermal Digestive Tract Development
Cellular Carbohydrate Metabolic Process
Positive Regulation Of Protein Binding
Regulation Of Viral Transcription
Tagcloud
?
adapter
assembly
danger
defense
discuss
engaged
framework
fungal
homeostasis
inducible
innate
lectin
links
lymphoid
lymphoma
malt
mucosa
multifunctional
nonredundant
oligomerization
paracaspase
polymorphisms
responds
rig
rlrs
sensors
spleen
syk
Tagcloud (Difference)
?
adapter
assembly
danger
defense
discuss
engaged
framework
fungal
homeostasis
inducible
innate
lectin
links
lymphoid
lymphoma
malt
mucosa
multifunctional
nonredundant
oligomerization
paracaspase
polymorphisms
responds
rig
rlrs
sensors
spleen
syk
Tagcloud (Intersection)
?