TBC1D10A and ACD

Number of citations of the paper that reports this interaction (PMID 21044950)
9

Data Source:
BioGRID (two hybrid)

		TBC1D10A	ACD
Gene Name		TBC1 domain family, member 10A	adrenocortical dysplasia homolog (mouse)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Microvillus Extracellular Vesicular Exosome	Chromosome, Telomeric Region Nuclear Telomere Cap Complex Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Rab GTPase Activator Activity Protein Binding PDZ Domain Binding	DNA Binding Protein Binding DNA Polymerase Binding
	Biological Process	Positive Regulation Of Rab GTPase Activity Retrograde Transport, Endosome To Golgi Positive Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Regulation Of Cilium Assembly	Telomere Maintenance Skeletal System Development Urogenital System Development Intracellular Protein Transport Telomere Capping Embryonic Limb Morphogenesis Protection From Non-homologous End Joining At Telomere Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Segmentation Positive Regulation Of Telomerase Activity Positive Regulation Of Single-stranded Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region
Pathways			Telomere Maintenance Packaging Of Telomere Ends DNA Damage/Telomere Stress Induced Senescence Chromosome Maintenance Cellular Senescence Meiotic synapsis
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ACD EZR GABARAPL1 MAP1LC3A SLC9A3R1 SLC9A3R2 TERF1 TERF2IP TEX13A	59 interactors: ACTB ADPRH AFAP1L2 AIPL1 ANKMY2 APOBEC3F BAG3 CKB CTTN DBN1 DBNL DCX DPYSL3 EIF3G EIF4B ENO2 ENSA FAM131B FKBP6 GAPDH HSP90AB1 IPO5 IVL LASP1 LDHA LGALSL LLGL1 LRRC25 NCDN NUDC NUDCD2 PAGE2 PDLIM2 PEX5 PFKP PGM2 POT1 RBKS RECQL4 RGS3 RPSA SBDS STIP1 STUB1 SULT1C2 TAGLN TBC1D10A TBCD TINF2 TOMM34 TRIM15 TRIM16 TUBB2A TUBB4B USP7 XRCC6 YWHAE ZFP36L1 ZNF790
Entrez ID		83874	65057
HPRD ID		18162	12417
Ensembl ID		ENSG00000099992	ENSG00000102977
Uniprot IDs		A7E244 B7ZVY9 Q20WK7 Q9BXI6	Q96AP0
PDB IDs			2I46
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Cellular Component Assembly Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomerase Organelle Organization Regulation Of Telomerase Activity Microvillus Assembly Microvillus Organization Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Nucleophagy RNA-dependent DNA Replication Regulation Of Chromosome Organization Mitochondrion Degradation Protein Localization To Chromosome Telomere Maintenance Via Telomere Lengthening Organelle Disassembly Autophagic Vacuole Assembly Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Macroautophagy Positive Regulation Of Single-stranded Telomeric DNA Binding Renal Phosphate Ion Absorption Negative Regulation Of DNA Recombination At Telomere Regulation Of Phosphatidylinositol 3-kinase Signaling Vacuole Organization Cellular Protein Localization Homeostatic Process Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of DNA Replication Membrane Fusion Cellular Response To Starvation Cellular Response To Stress Telomeric Loop Formation Age-dependent Telomere Shortening Autophagy Telomere Maintenance Via Telomere Shortening Cellular Response To Nutrient Levels Response To Starvation Renal Sodium Ion Transport Membrane To Membrane Docking	Organelle Organization Protein Folding Carbohydrate Catabolic Process Substantia Nigra Development Neural Nucleus Development 'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Nervous System Development Catabolic Process Cellular Component Assembly Midbrain Development Glycolytic Process Multicellular Organismal Development Negative Regulation Of Telomere Maintenance Via Telomerase Generation Of Neurons Telomere Assembly Pyruvate Metabolic Process Neurogenesis Developmental Process Negative Regulation Of Telomere Maintenance Monosaccharide Metabolic Process Regulation Of Cellular Protein Metabolic Process Brain Development Cellular Metabolic Process Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Head Development Glucose Metabolic Process Neuron Projection Development Neuron Projection Morphogenesis Telomere Maintenance Cell Differentiation Neuron Differentiation Regulation Of Protein Metabolic Process System Development DNA Duplex Unwinding DNA Geometric Change Regulation Of Telomere Maintenance Cellular Process Neuron Development Adherens Junction Organization Central Nervous System Development Pathogenesis Hexose Metabolic Process Cellular Carbohydrate Metabolic Process Negative Regulation Of DNA Metabolic Process Protein Polymerization Regulation Of Signaling Innate Immune Response DNA Metabolic Process
Tagcloud ?			acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86
Tagcloud (Difference) ?			acpra apng1 arg52 betaherpesvirus capsid carboxy carboxyl ccd corroborated counterparts cytomegalovirus deleting gal4 gammaherpesvirus hcmv his34 homologs maturational mcp pap proteinase replace scmv simian substituting transporting ul80 ul80a ul86
Tagcloud (Intersection) ?