TBC1D10A and GABARAPL1

Number of citations of the paper that reports this interaction (PMID 22354992)
16

Data Source:
BioGRID (affinity chromatography technology, pull down)

		TBC1D10A	GABARAPL1
Gene Name		TBC1 domain family, member 10A	GABA(A) receptor-associated protein like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Microvillus Extracellular Vesicular Exosome	Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Autophagic Vacuole Endoplasmic Reticulum Golgi Apparatus Cytosol Microtubule Extrinsic Component Of Membrane Cytoplasmic Vesicle Membrane Dendrite Membrane Dendrite Cytoplasm Cell Body
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Rab GTPase Activator Activity Protein Binding PDZ Domain Binding	Protein Binding Microtubule Binding Tat Protein Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Positive Regulation Of Rab GTPase Activity Retrograde Transport, Endosome To Golgi Positive Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Regulation Of Cilium Assembly	Autophagic Vacuole Assembly Mitochondrion Degradation Nucleophagy Membrane Fusion
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ACD EZR GABARAPL1 MAP1LC3A SLC9A3R1 SLC9A3R2 TERF1 TERF2IP TEX13A	35 interactors: AHNAK2 ATG4A ATG4B ATG4D CALCOCO2 DVL2 FAM134C FUNDC1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAPK15 OPRK1 RABGAP1 RABGAP1L SCYL3 SNCA SQSTM1 SRPK1 SRPK2 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B TNIP1 VDR
Entrez ID		83874	23710
HPRD ID		18162	07601
Ensembl ID		ENSG00000099992	ENSG00000139112
Uniprot IDs		A7E244 B7ZVY9 Q20WK7 Q9BXI6	Q9H0R8
PDB IDs			2L8J 2R2Q
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Cellular Component Assembly Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomerase Organelle Organization Regulation Of Telomerase Activity Microvillus Assembly Microvillus Organization Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Nucleophagy RNA-dependent DNA Replication Regulation Of Chromosome Organization Mitochondrion Degradation Protein Localization To Chromosome Telomere Maintenance Via Telomere Lengthening Organelle Disassembly Autophagic Vacuole Assembly Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Macroautophagy Positive Regulation Of Single-stranded Telomeric DNA Binding Renal Phosphate Ion Absorption Negative Regulation Of DNA Recombination At Telomere Regulation Of Phosphatidylinositol 3-kinase Signaling Vacuole Organization Cellular Protein Localization Homeostatic Process Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of DNA Replication Membrane Fusion Cellular Response To Starvation Cellular Response To Stress Telomeric Loop Formation Age-dependent Telomere Shortening Autophagy Telomere Maintenance Via Telomere Shortening Cellular Response To Nutrient Levels Response To Starvation Renal Sodium Ion Transport Membrane To Membrane Docking	Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Ras GTPase Activity Regulation Of Ras Protein Signal Transduction Regulation Of Ras GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Autophagy Regulation Of Catalytic Activity Regulation Of Signal Transduction Regulation Of Signaling Protein Delipidation Mitochondrion Degradation Organelle Disassembly Regulation Of Metabolic Process Macroautophagy Cellular Response To Nitrogen Starvation Retrograde Transport, Endosome To Golgi Cellular Response To Nutrient Levels Nucleophagy Response To Starvation C-terminal Protein Lipidation Endosomal Transport Cellular Response To Extracellular Stimulus Protein Processing Response To Nutrient Levels Positive Regulation Of Autophagy Response To Extracellular Stimulus Autophagic Vacuole Assembly Cellular Response To Starvation Negative Regulation Of Viral Genome Replication Regulation Of Viral Genome Replication Mitochondrion Organization Negative Regulation Of Viral Process Vacuole Organization Regulation Of Autophagy Positive Regulation Of Viral Genome Replication Protein Lipidation Intracellular Transport Lipoprotein Biosynthetic Process Cellular Localization Response To Stress Establishment Of Localization In Cell Positive Regulation Of Protein Metabolic Process
Tagcloud ?			2000mug 3f aminobutyric anabolism atg12 atg13 atg5 atrogin atrogin1 autophagosome beta2 bnip3 culminated e1b eb eif3 formoterol hydrolases kinase1 lc3b mafbx myod protein3 relativized sqstm1 tfeb tibialis ulk1 unc
Tagcloud (Difference) ?			2000mug 3f aminobutyric anabolism atg12 atg13 atg5 atrogin atrogin1 autophagosome beta2 bnip3 culminated e1b eb eif3 formoterol hydrolases kinase1 lc3b mafbx myod protein3 relativized sqstm1 tfeb tibialis ulk1 unc
Tagcloud (Intersection) ?