TBC1D10A and GABARAPL1

Number of citations of the paper that reports this interaction (PubMedID 22354992)
55

Data Source:
BioGRID (affinity chromatography technology, pull down)

		TBC1D10A	GABARAPL1
Description		TBC1 domain family member 10A	GABA type A receptor associated protein like 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Microvillus Cell Projection Extracellular Exosome	Autophagosome Membrane Cytoplasm Mitochondrion Autophagosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Microtubule Plasma Membrane Cilium Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Ciliary Basal Body
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding PDZ Domain Binding Cadherin Binding	Protein Binding Phospholipid Binding Phosphatidylethanolamine Binding Tat Protein Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Retrograde Transport, Endosome To Golgi Positive Regulation Of Proteolysis Regulation Of Cilium Assembly	Autophagosome Assembly Mitophagy Autophagy Cellular Response To Nitrogen Starvation Glycophagy Autophagosome Maturation
Pathways		TBC/RABGAPs	Macroautophagy
Drugs
Diseases
GWAS		Delirium ( 29631748) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		9 interacting genes: ACD EZR GABARAPL1 MAP1LC3A NHERF1 NHERF2 TERF1 TERF2IP TEX13A	87 interacting genes: AHNAK2 AMBRA1 ANK2 APPL1 ARFGAP1 ATG13 ATG4A ATG4B ATG4D AZI2 BICC1 BNIP3L BRD9 BSCL2 BSDC1 CALCOCO1 CALCOCO2 CARS2 CCT2 CDC37 CREB3L2 CUL3 DISC1 DVL2 DYNLL1 ERBB2 ERBB3 FUNDC1 G3BP1 KBTBD7 KRTAP10-3 KRTAP10-7 KRTAP10-9 KXD1 MAP4K2 MAPK15 MEFV MLX MYBPC1 NCOR1 NEDD4 NFIA NUFIP2 OPRK1 OPTN OSBPL3 PBXIP1 PSMB4 PTPRR RABGAP1 RABGAP1L RB1CC1 RCN2 RESF1 RETREG3 SCYL3 SEC62 SNCA SQSTM1 SRPK1 SRPK2 STK3 STRN3 TAX1BP1 TBC1D1 TBC1D10A TBC1D10B TBC1D16 TBC1D17 TBC1D2 TBC1D25 TBC1D2B TBC1D5 TBC1D7 TBC1D9 TBC1D9B THAP7 TMEM131 TNIP1 TP53INP1 TRIM21 TRIM25 TRIM32 UMAD1 VDR WDFY3 ZBTB22
Entrez ID		83874	23710
HPRD ID		18162	07601
Ensembl ID		ENSG00000099992	ENSG00000139112
Uniprot IDs		A7E244 B7ZVY9 Q9BXI6	Q9H0R8
PDB IDs			2L8J 2R2Q 5DPT 5LXH 5LXI 6HOI 6HOL 6YOO 7AA7 7AA9 7JHX 8X8A
Enriched GO Terms of Interacting Partners?		Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Type 2 Metabotropic Glutamate Receptor Binding Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Type 3 Metabotropic Glutamate Receptor Binding Negative Regulation Of Telomere Maintenance Phosphatase Binding Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome Microvillus Assembly Protection From Non-homologous End Joining At Telomere Positive Regulation Of Telomere Maintenance Microvillus Organization Negative Regulation Of Chromosome Organization DNA Biosynthetic Process G-rich Strand Telomeric DNA Binding Cellular Response To Nitrogen Starvation Protein Localization To Chromosome, Telomeric Region Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Phosphatidylethanolamine Binding Telomere Maintenance In Response To DNA Damage Cellular Component Assembly Telomere Organization Establishment Of Epithelial Cell Apical/basal Polarity Negative Regulation Of DNA Metabolic Process Organelle Organization Negative Regulation Of Telomere Maintenance Via Telomerase Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Microvillus Membrane Gland Morphogenesis Establishment Of Epithelial Cell Polarity Negative Regulation Of DNA Biosynthetic Process Protein Localization To Plasma Membrane Protein-membrane Adaptor Activity Protein Localization To Cell Periphery Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Via Telomerase Microtubule Binding Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity	Autophagosome Regulation Of Cilium Assembly Autophagy Macroautophagy GTPase Activator Activity Regulation Of Organelle Assembly Cytosol Regulation Of Autophagy Positive Regulation Of Autophagy Autophagy Of Mitochondrion Regulation Of Cell Projection Assembly Mitophagy Autophagosome Assembly Autophagosome Organization Aggrephagy Cytoplasmic Vesicle Piecemeal Microautophagy Of The Nucleus Cytoplasm Regulation Of Cell Projection Organization Microautophagy Nucleophagy Positive Regulation Of Catabolic Process Regulation Of Plasma Membrane Bounded Cell Projection Organization Vacuole Organization Regulation Of Organelle Organization Positive Regulation Of Metabolic Process Protein-phosphatidylethanolamide Deconjugating Activity Catabolic Process Protein Delipidation Response To Mitochondrial Depolarisation Organelle Assembly Regulation Of Macroautophagy Atg1/ULK1 Kinase Complex Regulation Of Cellular Component Organization Positive Regulation Of Macroautophagy Regulation Of Intracellular Signal Transduction Protein Polyubiquitination Negative Regulation Of Cell Communication Negative Regulation Of Signaling Regulation Of Signal Transduction Phagophore Assembly Site Negative Regulation Of Signal Transduction ERBB3:ERBB2 Complex Protein Localization To Phagocytic Vesicle Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Metabolic Process Response To Stress Regulation Of Signaling Regulation Of Cell Communication Negative Regulation Of Viral Process
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