TBC1D10A and SLC9A3R2

Number of citations of the paper that reports this interaction (PMID 11285285)
21

Data Source:
HPRD (in vitro)

		TBC1D10A	SLC9A3R2
Gene Name		TBC1 domain family, member 10A	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Microvillus Extracellular Vesicular Exosome	Nucleus Cytoplasm Plasma Membrane Focal Adhesion Endomembrane System Apical Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Rab GTPase Activator Activity Protein Binding PDZ Domain Binding	Receptor Binding Protein Binding Beta-catenin Binding Protein C-terminus Binding Phosphatase Binding
	Biological Process	Positive Regulation Of Rab GTPase Activity Retrograde Transport, Endosome To Golgi Positive Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Regulation Of Cilium Assembly	Protein Complex Assembly Negative Regulation Of Phosphatidylinositol 3-kinase Signaling
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ACD EZR GABARAPL1 MAP1LC3A SLC9A3R1 SLC9A3R2 TERF1 TERF2IP TEX13A	35 interactors: ABCC4 ACTN4 ADORA2B ADRB2 ATP2B2 CFTR EZR KCNJ1 LPAR1 LPAR2 P2RY1 PDPK1 PDZK1 PIK3CA PLCB3 PODXL PRKACA PTEN PTH1R RDX SGK1 SGK3 SIAH1 SLC22A4 SLC22A5 SLC22A9 SLC26A3 SLC34A1 SLC9A3 SLCO1A2 SLCO3A1 SRY TAZ TBC1D10A WWTR1
Entrez ID		83874	9351
HPRD ID		18162	05946
Ensembl ID		ENSG00000099992	ENSG00000065054
Uniprot IDs		A7E244 B7ZVY9 Q20WK7 Q9BXI6	Q15599
PDB IDs			2D11 2HE4 2OCS
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Cellular Component Assembly Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomerase Organelle Organization Regulation Of Telomerase Activity Microvillus Assembly Microvillus Organization Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Nucleophagy RNA-dependent DNA Replication Regulation Of Chromosome Organization Mitochondrion Degradation Protein Localization To Chromosome Telomere Maintenance Via Telomere Lengthening Organelle Disassembly Autophagic Vacuole Assembly Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Macroautophagy Positive Regulation Of Single-stranded Telomeric DNA Binding Renal Phosphate Ion Absorption Negative Regulation Of DNA Recombination At Telomere Regulation Of Phosphatidylinositol 3-kinase Signaling Vacuole Organization Cellular Protein Localization Homeostatic Process Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of DNA Replication Membrane Fusion Cellular Response To Starvation Cellular Response To Stress Telomeric Loop Formation Age-dependent Telomere Shortening Autophagy Telomere Maintenance Via Telomere Shortening Cellular Response To Nutrient Levels Response To Starvation Renal Sodium Ion Transport Membrane To Membrane Docking	Regulation Of Protein Kinase Activity Ion Homeostasis Transmembrane Transport Regulation Of Kinase Activity Regulation Of Ion Transport Positive Regulation Of Ion Transport Regulation Of Protein Phosphorylation Homeostatic Process Positive Regulation Of Transport Ion Transport Regulation Of Phosphorus Metabolic Process Positive Regulation Of Transferase Activity Regulation Of Phosphorylation Ion Transmembrane Transport Cellular Cation Homeostasis Organic Anion Transport Cellular Ion Homeostasis Cytosolic Calcium Ion Homeostasis Chemical Homeostasis Positive Regulation Of Protein Kinase Activity Blood Circulation Positive Regulation Of Cellular Protein Metabolic Process Anion Transport Platelet Activation Positive Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Transport Positive Regulation Of Protein Phosphorylation Sodium-independent Organic Anion Transport Carnitine Transport Cellular Chemical Homeostasis Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Body Fluid Levels Monocarboxylic Acid Transport Sperm Capacitation Anion Transmembrane Transport Regulation Of Cellular Component Organization Sodium Ion Transport Inorganic Anion Transport Regulation Of Cellular Protein Metabolic Process Response To Organonitrogen Compound Regulation Of Ion Transmembrane Transport Blood Coagulation Hemostasis Activation Of Protein Kinase Activity Positive Regulation Of Phosphorylation Quaternary Ammonium Group Transport Positive Regulation Of Cytosolic Calcium Ion Concentration
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