TBC1D10A and EZR

Number of citations of the paper that reports this interaction (PMID 11285285)
21

Data Source:
HPRD (in vitro, in vivo)

		TBC1D10A	EZR
Gene Name		TBC1 domain family, member 10A	ezrin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Microvillus Extracellular Vesicular Exosome	Ruffle Uropod Extracellular Space Nucleolus Cytosol Actin Filament Plasma Membrane Microvillus Focal Adhesion Actin Cytoskeleton Membrane Basolateral Plasma Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Filopodium T-tubule Cortical Cytoskeleton Microvillus Membrane Vesicle Ruffle Membrane Ciliary Basal Body Cell Body Microspike Membrane Raft Apical Part Of Cell Cell Tip Extracellular Vesicular Exosome Cell Periphery Astrocyte Projection Schwann Cell Microvillus
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Rab GTPase Activator Activity Protein Binding PDZ Domain Binding	Protein Binding Protein Domain Specific Binding Poly(A) RNA Binding Cell Adhesion Molecule Binding Actin Filament Binding
	Biological Process	Positive Regulation Of Rab GTPase Activity Retrograde Transport, Endosome To Golgi Positive Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Regulation Of Cilium Assembly	Cytoskeletal Anchoring At Plasma Membrane Leukocyte Cell-cell Adhesion Axon Guidance Regulation Of Cell Shape Positive Regulation Of Gene Expression Membrane To Membrane Docking Microvillus Assembly Receptor Internalization Establishment Of Epithelial Cell Apical/basal Polarity Filopodium Assembly Actin Filament Bundle Assembly Establishment Of Endothelial Barrier
Pathways			Axon guidance L1CAM interactions Netrin-1 signaling Recycling pathway of L1
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ACD EZR GABARAPL1 MAP1LC3A SLC9A3R1 SLC9A3R2 TERF1 TERF2IP TEX13A	49 interactors: ACTB ACTC1 ADORA2B ADRA1B ARF6 ARHGDIB CD44 CDH1 CDK5 CFTR CLIC5 CTNNB1 DLG1 EGFR FAS FASLG GZMM ICAM1 ICAM2 ICAM3 IQGAP1 L1CAM LCK MDM2 MPP3 MSN NF2 PALLD PIK3R1 PRKAR2A PRKCA PTK2 PTPRC RDX ROCK1 S100P SCYL3 SDC2 SELL SELP SLC9A3R1 SLC9A3R2 SPN TBC1D10A TMEM8B TSC1 VCAM1 WFDC1 WWOX
Entrez ID		83874	7430
HPRD ID		18162	00475
Ensembl ID		ENSG00000099992	ENSG00000092820
Uniprot IDs		A7E244 B7ZVY9 Q20WK7 Q9BXI6	P15311
PDB IDs			1NI2
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Cellular Component Assembly Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomerase Organelle Organization Regulation Of Telomerase Activity Microvillus Assembly Microvillus Organization Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Nucleophagy RNA-dependent DNA Replication Regulation Of Chromosome Organization Mitochondrion Degradation Protein Localization To Chromosome Telomere Maintenance Via Telomere Lengthening Organelle Disassembly Autophagic Vacuole Assembly Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Macroautophagy Positive Regulation Of Single-stranded Telomeric DNA Binding Renal Phosphate Ion Absorption Negative Regulation Of DNA Recombination At Telomere Regulation Of Phosphatidylinositol 3-kinase Signaling Vacuole Organization Cellular Protein Localization Homeostatic Process Negative Regulation Of Sodium:proton Antiporter Activity Glutathione Transport Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Regulation Of DNA Replication Membrane Fusion Cellular Response To Starvation Cellular Response To Stress Telomeric Loop Formation Age-dependent Telomere Shortening Autophagy Telomere Maintenance Via Telomere Shortening Cellular Response To Nutrient Levels Response To Starvation Renal Sodium Ion Transport Membrane To Membrane Docking	Cell Adhesion Single Organismal Cell-cell Adhesion Movement Of Cell Or Subcellular Component Locomotion Cell Migration Regulation Of Immune System Process Regulation Of Cell Adhesion Cell Motility Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Response To Organic Substance Leukocyte Migration Regulation Of Signaling Leukocyte Cell-cell Adhesion Organ Development Membrane To Membrane Docking Positive Regulation Of Cellular Protein Metabolic Process Response To Organonitrogen Compound Regulation Of Cell-cell Adhesion Cell Differentiation Immune System Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Immune Response Regulation Of Phosphorylation Cell Activation Apoptotic Process Regulation Of Protein Metabolic Process Programmed Cell Death Regulation Of Immune Response System Development Response To Growth Factor Cell Death Anatomical Structure Development Death Response To External Stimulus Positive Regulation Of Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Catalytic Activity Multicellular Organismal Development Blood Coagulation Developmental Process Hemostasis Defense Response Response To Radiation Positive Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Response To Stimulus Cell Development Regulation Of Body Fluid Levels
Tagcloud ?			actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom fsp1 genomelab hcellmarkerplex house hybridisation incorporates krt18 lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf
Tagcloud (Difference) ?			actg2 adenomatous archived b4ganlt2 bank casp3 cdx1 cdx2 classifier cnn1 col1a1 custom fsp1 genomelab hcellmarkerplex house hybridisation incorporates krt18 lgr5 ms4a12 muc2 mucin nox1 ntn1 polyp signatures slc9a2 vwf
Tagcloud (Intersection) ?