CHD1 and SAFB

Number of citations of the paper that reports this interaction (PubMedID 12890497)
0

Data Source:
HPRD (two hybrid, in vitro)

		CHD1	SAFB
Description		chromodomain helicase DNA binding protein 1	scaffold attachment factor B
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Chromatin Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Midbody
	Molecular Function	Nucleotide Binding DNA Binding Chromatin Binding Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Histone Binding Histone H3K4me3 Reader Activity ATP-dependent Chromatin Remodeler Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Nucleic Acid Binding DNA Binding Chromatin Binding Double-stranded DNA Binding RNA Binding Protein Binding Sequence-specific DNA Binding
	Biological Process	Chromatin Organization Chromatin Remodeling Nucleosome Organization Host-mediated Activation Of Viral Transcription	Chromatin Organization Regulation Of Transcription By RNA Polymerase II Estrogen Receptor Signaling Pathway Regulation Of MRNA Processing Regulation Of Androgen Receptor Signaling Pathway
Pathways		Estrogen-dependent gene expression	SUMOylation of transcription cofactors
Drugs
Diseases
GWAS		Basophil percentage of white cells ( 27863252) Eosinophil count ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Neutrophil percentage of granulocytes ( 27863252) Periodontitis (Mean PAL) ( 24024966) Renal sinus fat ( 22044751)	Mean reticulocyte volume ( 32888494)
Interacting Genes		9 interacting genes: BCLAF1 H3-3A H3-4 HDAC1 NCOR1 SAFB SPP1 SRSF3 SSRP1	30 interacting genes: ABHD16A CDC37 CEBPA CHD1 CHD3 CLK1 CSNK2A1 CYCS ESR1 HNRNPA1 HNRNPD HNRNPK IL7R LINC00941 MIR199A1 MIR363 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7D NCOR1 POLR2A SAFB2 SREK1 SRPK1 SRPK2 SRSF9 SUMO2 TAF15 TJP2
Entrez ID		1105	6294
HPRD ID		03668	04205
Ensembl ID		ENSG00000153922	ENSG00000160633
Uniprot IDs		A0A087WVF4 B3KT33 O14646	B7Z2F6 B7ZLP5 Q15424
PDB IDs		2B2T 2B2U 2B2V 2B2W 2B2Y 2N39 4B4C 4NW2 4O42 5AFW 8UMG
Enriched GO Terms of Interacting Partners?		Regulation Of Androgen Receptor Signaling Pathway Chromatin Organization Response To Macrophage Colony-stimulating Factor Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Nucleosome Assembly DNA Binding Negative Regulation Of Androgen Receptor Signaling Pathway Nucleosome Organization RNA Polymerase II Core Promoter Sequence-specific DNA Binding Response To Platelet-derived Growth Factor Protein-DNA Complex Assembly Response To Peptide Response To Cytokine Nucleoplasm Nucleosomal DNA Binding Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone Deacetylase Complex Embryo Implantation Chromatin Remodeling Heterochromatin Constitutive Heterochromatin Formation Adherens Junction Disassembly Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Transcription Repressor Complex Regulation Of Gene Expression Regulation Of RNA Metabolic Process Nucleus Regulation Of Macromolecule Biosynthetic Process Cell-cell Junction Disassembly Structural Constituent Of Chromatin Krueppel-associated Box Domain Binding Protein-RNA Sequence-specific Adaptor Activity Positive Regulation Of Estradiol Secretion Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Cytokine Stimulus Kit Signaling Pathway Protein Lysine Delactylase Activity Fungiform Papilla Formation Cellular Response To Leukemia Inhibitory Factor Response To Leukemia Inhibitory Factor Regulation Of Estradiol Secretion Male Gonad Development Cellular Response To Macrophage Colony-stimulating Factor Stimulus Negative Regulation Of Mast Cell Activation Involved In Immune Response Tyrosine Phosphorylation Of STAT Protein Regulation Of Macromolecule Metabolic Process Extracellular Matrix-cell Signaling Chromatin Gonad Development Nucleosome	Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulatory NcRNA-mediated Gene Silencing Regulation Of Metabolic Process Regulation Of RNA Splicing MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Regulation Of Gene Expression Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Regulation Of MRNA Processing Post-transcriptional Gene Silencing Regulation Of Primary Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process RISC Complex Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression RNA Splicing MRNA Base-pairing Post-transcriptional Repressor Activity Nucleoplasm Negative Regulation Of Metabolic Process Nucleic Acid Binding RNA Binding MRNA Metabolic Process Chromatin RNA Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of MRNA Metabolic Process Negative Regulation Of Interleukin-6-mediated Signaling Pathway Protein Domain Specific Binding Positive Regulation Of Catabolic Process MRNA 3'-UTR Binding Chromatin Organization Positive Regulation Of Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Processing DNA Binding Positive Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of MRNA Stability Nucleus Nucleic Acid Metabolic Process ATP-dependent Chromatin Remodeler Activity
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