CHD1 and SAFB

Number of citations of the paper that reports this interaction (PMID 12890497)
11

Data Source:
HPRD (two hybrid, in vitro)

		CHD1	SAFB
Gene Name		chromodomain helicase DNA binding protein 1	scaffold attachment factor B
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm
	Molecular Function	DNA Binding ATP-dependent DNA Helicase Activity Protein Binding ATP Binding Methylated Histone Binding	Nucleotide Binding Core Promoter Binding Chromatin Binding Double-stranded DNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter DNA Duplex Unwinding	Chromatin Organization Transcription, DNA-templated Intracellular Estrogen Receptor Signaling Pathway Growth Hormone Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs		Epirubicin
Diseases
GWAS		Renal sinus fat ( 22044751)
Protein-Protein Interactions		9 interactors: BCLAF1 H3F3A HDAC1 HIST3H3 NCOR1 SAFB SPP1 SRSF3 SSRP1	21 interactors: ABHD16A CDC37 CHD1 CHD3 CLK1 CSNK2A1 CYCS ESR1 HNRNPA1 HNRNPD HNRNPK IL7R MAP1LC3B NCOR1 POLR2A SAFB2 SREK1 SRPK1 SRSF9 TAF15 TJP2
Entrez ID		1105	6294
HPRD ID		03668	04205
Ensembl ID		ENSG00000153922	ENSG00000160633
Uniprot IDs		B3KT33 O14646	Q15424
PDB IDs		2B2T 2B2U 2B2V 2B2W 2B2Y 4B4C
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Organization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Transcription, DNA-templated Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Viral Transcription Organelle Organization Negative Regulation Of Gene Expression, Epigenetic RNA Metabolic Process Circadian Regulation Of Gene Expression Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Chromatin Modification Notch Signaling Pathway Regulation Of Growth Positive Regulation Of Cellular Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Viral Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Definitive Erythrocyte Differentiation Regulatory T Cell Differentiation Circadian Rhythm Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Transforming Growth Factor Beta Stimulus Chromatin Remodeling Regulation Of RNA Metabolic Process Response To Transforming Growth Factor Beta Negative Regulation Of Collateral Sprouting Regulation Of Gene Expression, Epigenetic	RNA Splicing Nucleobase-containing Compound Metabolic Process RNA Metabolic Process MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process MRNA Metabolic Process RNA Processing Nitrogen Compound Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated RNA Biosynthetic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Chromatin Organization Regulation Of Metabolic Process DNA-templated Transcription, Initiation Cellular Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Viral Process Rhythmic Process Chromatin Modification Metabolic Process Chromosome Organization Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Metabolic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated DNA Conformation Change Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Interleukin-7-mediated Signaling Pathway Transcription, RNA-templated Positive Regulation Of Viral Process RNA Export From Nucleus Execution Phase Of Apoptosis
Tagcloud ?		demand distinctly e5 e7 elongated engagement epiblast escs fail gastrulate globally grow highlighting intergenic normalized nucleoli output patterned pluripotent pol remodeler renewal ribosomal rnap sustain transcribed uncovered undergoes unusually	array bank comparing consistently differentially electrophoresis emphasizing follicular gel hundred luca lymphoma lymphomagenesis mad1l1 maldi mantle modest pooling programs proteome rad50 referenced relevance search seventy spots standardized tof translational
Tagcloud (Difference) ?		demand distinctly e5 e7 elongated engagement epiblast escs fail gastrulate globally grow highlighting intergenic normalized nucleoli output patterned pluripotent pol remodeler renewal ribosomal rnap sustain transcribed uncovered undergoes unusually	array bank comparing consistently differentially electrophoresis emphasizing follicular gel hundred luca lymphoma lymphomagenesis mad1l1 maldi mantle modest pooling programs proteome rad50 referenced relevance search seventy spots standardized tof translational
Tagcloud (Intersection) ?