CHD1 and BCLAF1

Number of citations of the paper that reports this interaction (PMID 12890497)
11

Data Source:
BioGRID (two hybrid)

		CHD1	BCLAF1
Gene Name		chromodomain helicase DNA binding protein 1	BCL2-associated transcription factor 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	DNA Binding ATP-dependent DNA Helicase Activity Protein Binding ATP Binding Methylated Histone Binding	DNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter DNA Duplex Unwinding	Transcription, DNA-templated Apoptotic Process Positive Regulation Of Apoptotic Process Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Transcription, DNA-templated Positive Regulation Of DNA-templated Transcription, Initiation Positive Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs		Epirubicin
Diseases
GWAS		Renal sinus fat ( 22044751)
Protein-Protein Interactions		9 interactors: BCLAF1 H3F3A HDAC1 HIST3H3 NCOR1 SAFB SPP1 SRSF3 SSRP1	9 interactors: BCL2 BCL2L1 CHD1 CLK1 CSNK2A1 EMD LEMD3 PIN1 YWHAG
Entrez ID		1105	9774
HPRD ID		03668	16544
Ensembl ID		ENSG00000153922	ENSG00000029363
Uniprot IDs		B3KT33 O14646	E9PK91 Q9NYF8
PDB IDs		2B2T 2B2U 2B2V 2B2W 2B2Y 4B4C
Enriched GO Terms of Interacting Partners?		Chromosome Organization Chromatin Organization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Gene Expression Transcription, DNA-templated Nitrogen Compound Metabolic Process RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Viral Transcription Organelle Organization Negative Regulation Of Gene Expression, Epigenetic RNA Metabolic Process Circadian Regulation Of Gene Expression Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Glycolytic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Differentiation Chromatin Modification Notch Signaling Pathway Regulation Of Growth Positive Regulation Of Cellular Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Viral Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Definitive Erythrocyte Differentiation Regulatory T Cell Differentiation Circadian Rhythm Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Transforming Growth Factor Beta Stimulus Chromatin Remodeling Regulation Of RNA Metabolic Process Response To Transforming Growth Factor Beta Negative Regulation Of Collateral Sprouting Regulation Of Gene Expression, Epigenetic	Regulation Of Mitochondrion Organization Regulation Of Signal Transduction Regulation Of Organelle Organization Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Negative Regulation Of Anoikis Regulation Of Signaling Regulation Of Cellular Component Organization Regulation Of Anoikis Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Release Of Cytochrome C From Mitochondria Cell Cycle Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Establishment Of Protein Localization Regulation Of Mitochondrial Membrane Permeability Mitotic Cell Cycle Process Positive Regulation Of Intracellular Transport Regulation Of Membrane Permeability Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Mitotic Cell Cycle Regulation Of Protein Localization Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Peptidyl-threonine Phosphorylation Response To Gamma Radiation Rhythmic Process Membrane Organization Neuron Apoptotic Process Positive Regulation Of Mitochondrion Organization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Skeletal Muscle Cell Differentiation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Apoptotic Signaling Pathway Mitochondrial Membrane Organization Neuron Death Ovarian Follicle Development Cellular Response To Organic Substance Apoptotic Process Apoptotic Mitochondrial Changes Organelle Organization Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Programmed Cell Death Regulation Of Cellular Localization Cell Cycle Process Negative Regulation Of Cellular PH Reduction
Tagcloud ?		demand distinctly e5 e7 elongated engagement epiblast escs fail gastrulate globally grow highlighting intergenic normalized nucleoli output patterned pluripotent pol remodeler renewal ribosomal rnap sustain transcribed uncovered undergoes unusually	abcb7 advance alas2 asxl1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon hnrnpd leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome
Tagcloud (Difference) ?		demand distinctly e5 e7 elongated engagement epiblast escs fail gastrulate globally grow highlighting intergenic normalized nucleoli output patterned pluripotent pol remodeler renewal ribosomal rnap sustain transcribed uncovered undergoes unusually	abcb7 advance alas2 asxl1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon hnrnpd leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome
Tagcloud (Intersection) ?