SRGN

Gene Name		serglycin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Golgi Apparatus Platelet Alpha Granule Lumen Zymogen Granule Mast Cell Granule
	Molecular Function	Protein Binding Collagen Binding
	Biological Process	Platelet Degranulation Blood Coagulation Granzyme-mediated Apoptotic Signaling Pathway Protein Processing Platelet Activation Negative Regulation Of Bone Mineralization Biomineral Tissue Development Mast Cell Secretory Granule Organization T Cell Secretory Granule Organization Maintenance Of Protease Location In Mast Cell Secretory Granule Maintenance Of Granzyme B Location In T Cell Secretory Granule Negative Regulation Of Cytokine Secretion
Pathways		Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-protein Interactions		12 interactors: ALB BAG6 CCL3 CD44 CEP70 GZMB PF4 PSRC1 SGTA UBQLN1 UBQLN4 UBR4
Entrez ID		5552
HPRD ID		01513
Ensembl ID		ENSG00000122862
Uniprot IDs		P10124
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Behavior Cytolysis Regulation Of Behavior Leukocyte Migration Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Leukocyte Chemotaxis Exocytosis Platelet Degranulation Negative Regulation Of Apoptotic Process Negative Regulation Of Myeloid Cell Differentiation Negative Regulation Of Programmed Cell Death Positive Regulation Of Leukocyte Migration Positive Regulation Of Monocyte Aggregation Maintenance Of Mitochondrion Location Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Cell Death Blood Coagulation Inflammatory Response Hemostasis Leukocyte Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Myeloid Leukocyte Differentiation Regulation Of Leukocyte Migration Monocyte Aggregation Response To Platinum Ion Negative Regulation Of Cytolysis Hemolysis By Symbiont Of Host Erythrocytes Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Eosinophil Degranulation Regulation Of Cellular Protein Metabolic Process Secretion By Cell Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Chemotaxis Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Natural Killer Cell Chemotaxis Granzyme-mediated Apoptotic Signaling Pathway Cellular Response To Interferon-gamma Regulation Of Body Fluid Levels Cellular Response To Cytokine Stimulus Positive Regulation Of Signal Transduction Regulation Of Intrinsic Apoptotic Signaling Pathway Immune System Process Response To Endoplasmic Reticulum Stress Regulation Of Protein Metabolic Process Negative Regulation Of MHC Class II Biosynthetic Process Wound Healing Immune Response
Tagcloud ?		bring btg1 cyr61 dcs e7 epha1 hla idc idcs igfbp3 igsf6 il8 kpna7 mdc mdcs mrps11 ncr3 nfkb1a nfkbia padre pgf pidc pulsed pulsing rad21 sema6a trem2 tubal3 txnrd1