SRGN and UBQLN1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SRGN	UBQLN1
Gene Name		serglycin	ubiquilin 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Golgi Apparatus Platelet Alpha Granule Lumen Zymogen Granule Mast Cell Granule	Proteasome Complex Nucleoplasm Cytoplasm Endoplasmic Reticulum Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Collagen Binding	Protein Binding Kinase Binding Protein Domain Specific Binding
	Biological Process	Platelet Degranulation Blood Coagulation Granzyme-mediated Apoptotic Signaling Pathway Protein Processing Platelet Activation Negative Regulation Of Bone Mineralization Biomineral Tissue Development Mast Cell Secretory Granule Organization T Cell Secretory Granule Organization Maintenance Of Protease Location In Mast Cell Secretory Granule Maintenance Of Granzyme B Location In T Cell Secretory Granule Negative Regulation Of Cytokine Secretion	Regulation Of Protein Ubiquitination Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ALB BAG6 CCL3 CD44 CEP70 GZMB PF4 PSRC1 SGTA UBQLN1 UBQLN4 UBR4	151 interactors: ABCC2 ACOT7 ADRM1 AGPAT5 AGR2 AGR3 APP ASCL1 ATXN3 BPIFA1 C1QA C1QTNF2 CALU CARKD CCL7 CCNB1 CD47 CD99 CD99L2 CHGB CHRNA3 CHRNA4 CHRNB4 COL10A1 COL1A2 COLGALT2 COMTD1 CSTF2 CSTF2T CTAG1B CTAG2 CYB5R1 DEFA6 DNAJB2 EFEMP2 EP300 EPS15 ERP27 ETNK1 F8 FAM127A FAM127B FAM127C FAM189A2 FAM86B3P FAS FBXO25 FCGR2A FGF7 FKBP2 FN1 FZD7 GABRA1 GABRA2 GABRA3 GABRA6 GABRB1 GABRB2 GABRB3 GABRD GHRL GIT2 GKAP1 GPX3 GRM2 GYPB HERC3 HES1 HGS HK2 HSD17B12 HSPA13 IGL IGLC1 IGLV2-14 IL6ST IST1 ITPRIPL1 KLHL42 LITAF MANBAL MCM7 MIEF1 MIEF2 MLLT6 MTOR NBL1 NDE1 NGLY1 NME3 NPPA NPY NUPL1 P4HB PBXIP1 PIK3IP1 PLA2G16 PNMA1 PPIB PPIC PRAP1 PRB1 PRPF40A PSEN1 PSEN2 PSMD4 PSMD6 PTN RARA RASSF5 RIC8A RNF208 RPN1 RSRC2 SCG5 SCMH1 SERPINE1 SERPINI2 SIL1 SLC29A2 SMAD9 SMIM2 SMR3B SPARC SRGN STMN3 TARDBP TFF1 TICAM1 TMCO6 TMEM31 TMEM37 TMUB2 TNFRSF1A TNFRSF1B TREX1 TRIM32 TXNDC12 UBB UBC UBE2V1 UBQLN4 UBXN1 UBXN4 VCP XPO4 ZFAND2B ZG16 ZG16B ZMYM4 ZNF343
Entrez ID		5552	29979
HPRD ID		01513	05440
Ensembl ID		ENSG00000122862	ENSG00000135018
Uniprot IDs		P10124	Q9UMX0
PDB IDs			2JY5 2JY6 2KLC
Enriched GO Terms of Interacting Partners?		Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Behavior Cytolysis Regulation Of Behavior Leukocyte Migration Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Leukocyte Chemotaxis Exocytosis Platelet Degranulation Negative Regulation Of Apoptotic Process Negative Regulation Of Myeloid Cell Differentiation Negative Regulation Of Programmed Cell Death Positive Regulation Of Leukocyte Migration Positive Regulation Of Monocyte Aggregation Maintenance Of Mitochondrion Location Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Cell Death Blood Coagulation Inflammatory Response Hemostasis Leukocyte Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Myeloid Leukocyte Differentiation Regulation Of Leukocyte Migration Monocyte Aggregation Response To Platinum Ion Negative Regulation Of Cytolysis Hemolysis By Symbiont Of Host Erythrocytes Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Eosinophil Degranulation Regulation Of Cellular Protein Metabolic Process Secretion By Cell Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Chemotaxis Negative Regulation Of Megakaryocyte Differentiation Positive Regulation Of Natural Killer Cell Chemotaxis Granzyme-mediated Apoptotic Signaling Pathway Cellular Response To Interferon-gamma Regulation Of Body Fluid Levels Cellular Response To Cytokine Stimulus Positive Regulation Of Signal Transduction Regulation Of Intrinsic Apoptotic Signaling Pathway Immune System Process Response To Endoplasmic Reticulum Stress Regulation Of Protein Metabolic Process Negative Regulation Of MHC Class II Biosynthetic Process Wound Healing Immune Response	Response To Stress Response To Organic Substance Positive Regulation Of Proteolysis Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Positive Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Response To Stimulus Regulation Of Protein Metabolic Process Cellular Response To Histamine Cellular Response To Organic Substance Cell-cell Signaling Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Synaptic Transmission Platelet Degranulation Signal Transduction Regulation Of Protein Ubiquitination Regulation Of Protein Catabolic Process Regulation Of ERBB Signaling Pathway Response To Histamine Chloride Transmembrane Transport Response To Organic Cyclic Compound Positive Regulation Of Protein Catabolic Process Signaling Cell Surface Receptor Signaling Pathway Response To Abiotic Stimulus Gamma-aminobutyric Acid Signaling Pathway Response To Hypoxia Cell Communication Chloride Transport Notch Signaling Pathway Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Immune System Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Cellular Response To Oxygen Levels Regulation Of Cellular Process Defense Response Positive Regulation Of Cell Cycle Cellular Response To Ammonium Ion Notch Receptor Processing Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Tagcloud ?		bring btg1 cyr61 dcs e7 epha1 hla idc idcs igfbp3 igsf6 il8 kpna7 mdc mdcs mrps11 ncr3 nfkb1a nfkbia padre pgf pidc pulsed pulsing rad21 sema6a trem2 tubal3 txnrd1	affecting aid biomarkers biosynthesis contamination differentially elucidated evaluating exert exposed hepatic hepatotoxicity hnrnpc huwe1 itraq labeling ontology paf1 perfluorinated perfluorooctane pfos proteomic splicing sulfonate technology toxic transduction trigger whose
Tagcloud (Difference) ?		bring btg1 cyr61 dcs e7 epha1 hla idc idcs igfbp3 igsf6 il8 kpna7 mdc mdcs mrps11 ncr3 nfkb1a nfkbia padre pgf pidc pulsed pulsing rad21 sema6a trem2 tubal3 txnrd1	affecting aid biomarkers biosynthesis contamination differentially elucidated evaluating exert exposed hepatic hepatotoxicity hnrnpc huwe1 itraq labeling ontology paf1 perfluorinated perfluorooctane pfos proteomic splicing sulfonate technology toxic transduction trigger whose
Tagcloud (Intersection) ?