KASH5 and PIGU

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KASH5	PIGU
Description		KASH domain containing 5	phosphatidylinositol glycan anchor biosynthesis class U
Image
GO Annotations	Cellular Component	Chromosome, Telomeric Region Lateral Element Nucleus Nuclear Envelope Nuclear Outer Membrane Chromosome Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Meiotic Spindle Pole	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane GPI-anchor Transamidase Complex
	Molecular Function	Protein Binding Identical Protein Binding Dynein Complex Binding	GPI-anchor Transamidase Activity Protein Binding GPI Anchor Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Actin Filament Organization Homologous Chromosome Pairing At Meiosis Spermatogenesis Telomere Localization Meiotic Telomere Clustering Oogenesis Spindle Assembly Meiotic Cell Cycle Spindle Localization Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation	GPI Anchor Biosynthetic Process Attachment Of GPI Anchor To Protein Regulation Of Receptor Signaling Pathway Via JAK-STAT GPI Anchored Protein Biosynthesis
Pathways			Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756) Brown vs. black hair color ( 30531825) Colorectal cancer or advanced adenoma ( 30510241) Cutaneous melanoma or hair colour ( 32341527) Estimated glomerular filtration rate ( 31152163) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Melanoma ( 28212542) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Smoking status (ever vs never smokers) ( 30643258) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Weight ( 28552196)
Interacting Genes		112 interacting genes: ABHD1 ADIPOQ ANKRD46 ATF7 BAG5 BCL2L2 BET1 C14orf180 CCDC120 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CMTM5 CRABP2 CTXN3 CWF19L2 CXCL16 CXCL9 CYBC1 DERL1 DNAJC30 EFNA5 EMD FAM161A FAM241B FAM50B FAM90A1 FATE1 FIS1 FRA10AC1 FTCD FXYD3 GABARAPL2 GALNT2 GIMAP5 GOSR2 GPATCH4 GPR25 HMOX1 ITGAM ITM2B JAGN1 KDM1A LARP1 LAT LENG1 LHFPL5 LMNA LRCH4 MALL MARCHF2 MMP14 MOSPD3 MS4A1 MTX2 NRIP3 NSG1 NTAQ1 OLFM4 PDGFRA PGAP2 PGRMC1 PIGU PLP2 PLPP6 PPP1R18 RIPPLY2 RNF146 RSPH14 RSRC2 RTP2 SENP2 SERP2 SGTA SHMT2 SLC30A2 SLC35B4 SLC41A1 SLC41A2 SLC5A4 SLC61A1 SLN SMCO4 SNAP47 STBD1 STX12 STX5 TCF25 TMEM11 TMEM147 TMEM14C TMEM19 TMEM41A TMEM86A TMPRSS4 TNF TRAF3IP3 TRARG1 TSHZ3 TTC23 UPK1B UPK2 VAMP1 VAMP2 VAMP4 VMA12 VTI1B ZC2HC1C ZFPL1 ZNF250	4 interacting genes: F2RL1 GPAA1 KASH5 WEE2-AS1
Entrez ID		147872	128869
HPRD ID		08134	12250
Ensembl ID		ENSG00000161609	ENSG00000101464
Uniprot IDs		Q8N6L0	Q9H490
PDB IDs		6R2I 6WMF	7W72 7WLD 8IMX 8IMY
Enriched GO Terms of Interacting Partners?		Membrane SNARE Complex SNAP Receptor Activity Protein Binding Endoplasmic Reticulum Membrane Vesicle Fusion Organelle Fusion Organelle Membrane Fusion Membrane Fusion Endoplasmic Reticulum SNARE Binding Membrane Organization Localization Within Membrane Vesicle Organization Presynaptic Endosome Membrane SNARE Complex Assembly Mitochondrial Outer Membrane Establishment Of Protein Localization To Membrane Golgi Membrane Endosome To Plasma Membrane Protein Transport Positive Regulation Of Neutrophil Activation Regulation Of Cellular Localization Monoatomic Cation Transmembrane Transporter Activity Vesicle-mediated Transport Endomembrane System Establishment Of Protein Localization To Plasma Membrane	Proteinase-activated Receptor Activity Positive Regulation Of Glomerular Filtration Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Regulation Of Renin Secretion Into Blood Stream Positive Regulation Of Eosinophil Degranulation Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Positive Regulation Of Renin Secretion Into Blood Stream GPI-anchor Transamidase Activity Meiotic Spindle Pole Mature Conventional Dendritic Cell Differentiation Positive Regulation Of Killing Of Cells Of Another Organism Thrombin-activated Receptor Activity GPI-anchor Transamidase Complex GPI Anchored Protein Biosynthesis Pre-mRNA 5'-splice Site Binding Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Neutrophil Mediated Cytotoxicity Attachment Of GPI Anchor To Protein Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Protein Retention In ER Lumen Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation MRNA 5'-splice Site Recognition GPI Anchor Binding Telomere Localization Regulation Of Toll-like Receptor 3 Signaling Pathway Thrombin-activated Receptor Signaling Pathway Positive Regulation Of Defense Response To Bacterium Positive Regulation Of Actin Filament Depolymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Phagocytosis, Engulfment Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Glomerular Filtration Maintenance Of Protein Localization In Endoplasmic Reticulum Meiotic Nuclear Membrane Microtubule Tethering Complex Lateral Element Regulation Of Defense Response To Bacterium Pseudopodium Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Positive Regulation Of Protein Depolymerization Renal System Process Involved In Regulation Of Systemic Arterial Blood Pressure Regulation Of Superoxide Anion Generation Cell-cell Junction Maintenance Positive Regulation Of Superoxide Anion Generation G-protein Beta-subunit Binding Dynein Complex Binding U1 SnRNP Positive Regulation Of Positive Chemotaxis Positive Regulation Of Rho Protein Signal Transduction
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?