KASH5 and FAM241B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KASH5	FAM241B
Description		KASH domain containing 5	family with sequence similarity 241 member B
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Lateral Element Nucleus Nuclear Envelope Nuclear Outer Membrane Chromosome Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex Meiotic Spindle Pole	Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Identical Protein Binding Dynein Complex Binding	Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination Actin Filament Organization Homologous Chromosome Pairing At Meiosis Spermatogenesis Telomere Localization Meiotic Telomere Clustering Oogenesis Spindle Assembly Meiotic Cell Cycle Spindle Localization Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation
Pathways
Drugs
Diseases
GWAS			Type 2 diabetes ( 30054458)
Interacting Genes		112 interacting genes: ABHD1 ADIPOQ ANKRD46 ATF7 BAG5 BCL2L2 BET1 C14orf180 CCDC120 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CMTM5 CRABP2 CTXN3 CWF19L2 CXCL16 CXCL9 CYBC1 DERL1 DNAJC30 EFNA5 EMD FAM161A FAM241B FAM50B FAM90A1 FATE1 FIS1 FRA10AC1 FTCD FXYD3 GABARAPL2 GALNT2 GIMAP5 GOSR2 GPATCH4 GPR25 HMOX1 ITGAM ITM2B JAGN1 KDM1A LARP1 LAT LENG1 LHFPL5 LMNA LRCH4 MALL MARCHF2 MMP14 MOSPD3 MS4A1 MTX2 NRIP3 NSG1 NTAQ1 OLFM4 PDGFRA PGAP2 PGRMC1 PIGU PLP2 PLPP6 PPP1R18 RIPPLY2 RNF146 RSPH14 RSRC2 RTP2 SENP2 SERP2 SGTA SHMT2 SLC30A2 SLC35B4 SLC41A1 SLC41A2 SLC5A4 SLC61A1 SLN SMCO4 SNAP47 STBD1 STX12 STX5 TCF25 TMEM11 TMEM147 TMEM14C TMEM19 TMEM41A TMEM86A TMPRSS4 TNF TRAF3IP3 TRARG1 TSHZ3 TTC23 UPK1B UPK2 VAMP1 VAMP2 VAMP4 VMA12 VTI1B ZC2HC1C ZFPL1 ZNF250	27 interacting genes: ADRA1A BIK BLCAP BNIP3 CD79A CGRRF1 CISD2 ERBB2 ERBB3 ERBB4 HSD17B11 KASH5 MOSPD1 MTNR1A REEP4 RNF185 RNF5 SCN3B SLC10A1 SLC39A11 SLC7A1 SUSD6 SYNE4 TMEM234 TMX2 TRHR ZDHHC15
Entrez ID		147872	219738
HPRD ID		08134	12573
Ensembl ID		ENSG00000161609	ENSG00000171224
Uniprot IDs		Q8N6L0	Q96D05
PDB IDs		6R2I 6WMF
Enriched GO Terms of Interacting Partners?		Membrane SNARE Complex SNAP Receptor Activity Protein Binding Endoplasmic Reticulum Membrane Vesicle Fusion Organelle Fusion Organelle Membrane Fusion Membrane Fusion Endoplasmic Reticulum SNARE Binding Membrane Organization Localization Within Membrane Vesicle Organization Presynaptic Endosome Membrane SNARE Complex Assembly Mitochondrial Outer Membrane Establishment Of Protein Localization To Membrane Golgi Membrane Endosome To Plasma Membrane Protein Transport Positive Regulation Of Neutrophil Activation Regulation Of Cellular Localization Monoatomic Cation Transmembrane Transporter Activity Vesicle-mediated Transport Endomembrane System Establishment Of Protein Localization To Plasma Membrane	Membrane ERBB3:ERBB2 Complex Basal Plasma Membrane ERBB2 Signaling Pathway Neuregulin Receptor Activity Protein Localization To Postsynapse ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Basolateral Plasma Membrane Ubiquitin-like Protein Conjugating Enzyme Binding Endoplasmic Reticulum ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Mitochondrial Fragmentation Involved In Apoptotic Process Protein Localization To Synapse Meiotic Nuclear Membrane Microtubule Tethering Complex Epidermal Growth Factor Receptor Signaling Pathway Apoptotic Mitochondrial Changes Mitochondrial Membrane Endoplasmic Reticulum Mannose Trimming Receptor Complex ERBB Signaling Pathway Protein Localization To Cell Junction Protein Alpha-1,2-demannosylation Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Protein Deglycosylation Glial Cell Differentiation Endoplasmic Reticulum Quality Control Compartment Positive Regulation Of Release Of Cytochrome C From Mitochondria Peripheral Nervous System Development Heart Development Positive Regulation Of Heart Rate Endoplasmic Reticulum Membrane Protein Tyrosine Kinase Activity Nuclear Outer Membrane Protein Localization To Postsynaptic Membrane Protein Localization To Membrane Negative Regulation Of Heart Rate Involved In Baroreceptor Response To Increased Systemic Arterial Blood Pressure Positive Regulation Of Heart Contraction Mitochondrion Autophagosome Adaptor Activity Establishment Of Planar Polarity Involved In Nephron Morphogenesis Thyrotropin-releasing Hormone Receptor Activity Regulation Of Release Of Cytochrome C From Mitochondria Oligodendrocyte Differentiation Apoptotic Process Growth Factor Binding Cell Death Positive Regulation Of The Force Of Heart Contraction By Epinephrine-norepinephrine
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