CCDC155 and MMP14

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CCDC155	MMP14
Gene Name		coiled-coil domain containing 155	matrix metallopeptidase 14 (membrane-inserted)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Chromosome, Telomeric Region Lateral Element Nuclear Outer Membrane Integral Component Of Membrane	Cytoplasm Golgi Lumen Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Extracellular Matrix Melanosome
	Molecular Function	Identical Protein Binding Dynein Complex Binding	Sequence-specific DNA Binding Transcription Factor Activity Metalloendopeptidase Activity Integrin Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Peptidase Activator Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination Spermatogenesis Oogenesis Chromosome Localization To Nuclear Envelope Involved In Synapsis	Angiogenesis Ovarian Follicle Development Response To Hypoxia Endothelial Cell Proliferation Endochondral Ossification Regulation Of Transcription, DNA-templated Proteolysis Response To Oxidative Stress Male Gonad Development Response To Mechanical Stimulus Positive Regulation Of Peptidase Activity Extracellular Matrix Disassembly Extracellular Matrix Organization Positive Regulation Of Cell Growth Lung Development Positive Regulation Of Cell Migration Collagen Catabolic Process Zymogen Activation Endodermal Cell Differentiation Chondrocyte Proliferation Astrocyte Cell Migration Response To Estrogen Embryonic Cranial Skeleton Morphogenesis Branching Morphogenesis Of An Epithelial Tube Tissue Remodeling Negative Regulation Of Focal Adhesion Assembly Craniofacial Suture Morphogenesis
Pathways			Collagen degradation Activation of Matrix Metalloproteinases Degradation of the extracellular matrix
Drugs
Diseases
GWAS
Protein-Protein Interactions		70 interactors: ABHD1 ADIPOQ ATF7 BAG5 BCL2L2 BET1 C17orf62 CCDC87 CDC73 CDKL3 CIB3 CLDN8 CRABP2 CXCL16 CXCL9 FAM161A FAM90A1 FATE1 FIS1 FRA10AC1 FTCD GABARAPL2 GALNT2 GOSR2 GPATCH4 GPR25 HMOX1 ITM2B JAGN1 KDM1A LARP1 LENG1 LHFPL5 MALL MARCH2 MFSD5 MMP14 MS4A1 MTX2 NRIP3 NSG1 OLFM4 PDGFRA PLP2 PPP1R18 RIPPLY2 RNF146 RSRC2 RTP2 SENP2 SERP2 SGTA SLC30A2 SLC41A2 SLN SMCO4 STBD1 STX5 TCF25 TMEM14C TMEM199 TMEM41A TMPRSS4 TRAF3IP3 TSHZ3 UPK1B UPK2 VAMP1 VAMP4 ZNF250	23 interactors: ACAN ADI1 BCAR1 C1QBP CAV1 CCDC155 CCL7 CLDN1 F12 ITGAV KISS1 LRP1 LUM MMP13 MMP2 PLLP RRAD SDC1 SPOCK1 SPOCK3 TIMP2 TIMP3 TIMP4
Entrez ID		147872	4323
HPRD ID		08134	02856
Ensembl ID		ENSG00000161609	ENSG00000157227
Uniprot IDs		Q8N6L0	P50281
PDB IDs			1BQQ 1BUV 3C7X 3MA2
Enriched GO Terms of Interacting Partners?		Membrane Fusion Organelle Fusion Vesicle Fusion Vesicle Fusion With Golgi Apparatus Negative Regulation Of Binding Membrane Organization Vesicle Organization Organelle Disassembly T Cell Chemotaxis SNARE Complex Assembly Negative Regulation Of Protein Binding Regulation Of Binding Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Intracellular Signal Transduction Regulation Of Intrinsic Apoptotic Signaling Pathway Vesicle-mediated Transport Regulation Of Cellular Component Organization Lymphocyte Chemotaxis Granulocyte Differentiation Endothelial Cell Proliferation T Cell Migration Transport Epithelial Cell Proliferation Low-density Lipoprotein Particle Clearance Embryo Development Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway ER To Golgi Vesicle-mediated Transport Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Metanephros Development Mitochondrion Degradation Lymphocyte Migration Establishment Of Protein Localization Response To Linoleic Acid Positive Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Renal Albumin Absorption Negative Regulation Of Metanephric Mesenchymal Cell Migration Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Positive Regulation Of Metanephric Glomerular Visceral Epithelial Cell Development Detection Of Oxidative Stress Kidney Smooth Muscle Cell Differentiation Ureteric Peristalsis Regulation Of Primitive Erythrocyte Differentiation Granulocyte Colony-stimulating Factor Signaling Pathway Molybdate Ion Transport	Negative Regulation Of Membrane Protein Ectodomain Proteolysis Negative Regulation Of Metalloenzyme Activity Extracellular Matrix Organization Extracellular Structure Organization Regulation Of Protein Processing Regulation Of Peptidase Activity Extracellular Matrix Disassembly Response To Wounding Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Negative Regulation Of Protein Metabolic Process Regulation Of Body Fluid Levels Sulfur Compound Metabolic Process Wound Healing Negative Regulation Of Proteolysis Response To Stimulus Glycosaminoglycan Catabolic Process Glycosaminoglycan Metabolic Process Negative Regulation Of Protein Processing System Development Anatomical Structure Development Regulation Of Endopeptidase Activity Regulation Of Proteolysis Negative Regulation Of Hydrolase Activity Regulation Of Cellular Component Movement Blood Coagulation Hemostasis Keratan Sulfate Catabolic Process Response To Organic Substance Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Developmental Process Regulation Of Protein Metabolic Process Multicellular Organismal Development Blood Coagulation, Intrinsic Pathway Glycosaminoglycan Biosynthetic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Proteoglycan Metabolic Process Response To External Stimulus Negative Regulation Of Protein Catabolic Process Regulation Of Cell Migration Response To Hormone Positive Regulation Of Cell Migration Keratan Sulfate Biosynthetic Process Positive Regulation Of Cell Motility Regulation Of Cell Motility Regulation Of Cellular Component Organization Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Keratan Sulfate Metabolic Process
Tagcloud ?			5p analyze diagnostics differentially focused functionally hcc hepatocarcinogenesis hepatocellular hepatoma identifying inhibiting invasion metalloproteinase microarray migration mir mirna mirnas pair progress promotes qpcr re reverses suppresses tissues validated worldwide
Tagcloud (Difference) ?			5p analyze diagnostics differentially focused functionally hcc hepatocarcinogenesis hepatocellular hepatoma identifying inhibiting invasion metalloproteinase microarray migration mir mirna mirnas pair progress promotes qpcr re reverses suppresses tissues validated worldwide
Tagcloud (Intersection) ?