FSD2 and FAM50B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FSD2	FAM50B
Description		fibronectin type III and SPRY domain containing 2	family with sequence similarity 50 member B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Midbody Intercellular Bridge
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Chromatin Organization
Pathways
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Tourette syndrome ( 30818990)	Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin) ( 23648065)
Interacting Genes		93 interacting genes: AQP1 ARFIP2 ATF7IP2 ATG14 ATXN7L2 BEX2 BEX3 BRD8 C1orf216 CAMSAP3 CBX8 CCDC112 CCDC120 CCDC146 CCDC187 CCHCR1 CDC73 CDK18 CORO1A CTAG1A CTAG1B CWF19L2 DCX DTNB ENKD1 EXOC3 FAM107A FAM110A FAM161A FAM50B FAM90A1 FARS2 FMR1 HDAC4 HGS IFT20 KANSL1 KLHL40 LATS1 LENG1 LNX1 MCRS1 MID2 MRPL11 MYBPC2 NDN OIP5 OXNAD1 PBX3 PIK3R3 PNMA5 POLL PPP1R18 PPP2R5D PRPF18 PRPF31 PSMB4 RCOR3 RNF8 SCNM1 SH2D4A SMARCE1 SNAPIN SPATC1L TCEANC THAP7 TLE5 TSGA10IP TTC23 UBTFL1 VEZF1 ZBTB38 ZC2HC1C ZMAT2 ZNF124 ZNF20 ZNF230 ZNF35 ZNF408 ZNF410 ZNF417 ZNF490 ZNF572 ZNF580 ZNF581 ZNF587 ZNF648 ZNF76 ZNF774 ZNF777 ZNF835 ZNF837 ZSCAN26	49 interacting genes: ACTN2 ADRA1A BICD2 CARD9 CCDC136 CCDC57 CCDC85B CCDC89 CCNC CDR2 DEUP1 FSD2 GFAP GMCL1 GOLGA2 GRIPAP1 HAP1 HOOK2 IKZF1 KASH5 KPNA3 KPNA4 KRT31 KRT34 LDOC1 LZTS1 LZTS2 MID1 MID2 MLH1 NUTF2 PAX6 PDE4DIP PIBF1 PSMB1 RABEP1 TACC1 TBC1D1 TFIP11 TRAF2 TRIM14 TRIM37 TRIM54 UBL5 VAC14 VPS52 WBP4 ZMYND12 ZRANB1
Entrez ID		123722	26240
HPRD ID		17291	16883
Ensembl ID		ENSG00000186628	ENSG00000145945
Uniprot IDs		A1L4K1 B7ZM05	Q9Y247
PDB IDs
Enriched GO Terms of Interacting Partners?		Zinc Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Gene Expression Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Identical Protein Binding Regulation Of Metabolic Process Centriole Microtubule Anchoring Microtubule Binding	Microtubule-based Process Cytoskeleton Organization Microtubule Cytoskeleton Organization Cytoskeleton Organelle Organization Cytoplasm Intracellular Protein Localization Protein Binding Protein Localization To Organelle Identical Protein Binding Nuclear Import Signal Receptor Activity Protein Transport Cellular Localization Intracellular Transport Spindle Organization Microtubule Organizing Center Organization Nuclear Pore Regulation Of Microtubule-based Process Centrosome Establishment Of Protein Localization Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Establishment Of Localization In Cell Telomere Localization Organelle Localization NLS-dependent Protein Nuclear Import Complex Protein Localization To Cytoskeleton Microtubule Microtubule Cytoskeleton Organization Involved In Mitosis Ubiquitin Protein Ligase Activity Spindle Midzone Assembly Cellular Component Assembly Protein Localization To Microtubule Microtubule Binding Positive Regulation Of Synaptic Transmission, GABAergic Enzyme Binding Negative Regulation Of Viral Transcription Membraneless Organelle Assembly Intermediate Filament Organization Regulation Of Microtubule Cytoskeleton Organization Transcription Coactivator Activity Positive Regulation Of Stress-activated MAPK Cascade Regulation Of Endocytic Recycling Regulation Of Viral Transcription Chromosome Localization Dynein Complex Binding Response To Muramyl Dipeptide
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