FSD2 and PIK3R3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FSD2	PIK3R3
Gene Name		fibronectin type III and SPRY domain containing 2	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytosol Phosphatidylinositol 3-kinase Complex
	Molecular Function		Protein Binding 1-phosphatidylinositol-3-kinase Activity Phosphatidylinositol 3-kinase Regulator Activity
	Biological Process		Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Insulin Receptor Signaling Pathway Phosphatidylinositol-3-phosphate Biosynthetic Process Regulation Of Phosphatidylinositol 3-kinase Activity Small Molecule Metabolic Process
Pathways			Signaling by the B Cell Receptor (BCR) Signaling by GPCR Metabolism of lipids and lipoproteins Signaling by FGFR in disease Signaling by EGFRvIII in Cancer Signaling by SCF-KIT Downstream signaling events of B Cell Receptor (BCR) DAP12 signaling PI3K/AKT activation Interleukin receptor SHC signaling PI-3K cascade Gastrin-CREB signalling pathway via PKC and MAPK Interleukin-7 signaling Phospholipid metabolism Signaling by PDGF DAP12 interactions GAB1 signalosome G-protein beta:gamma signalling CD28 co-stimulation CD28 dependent PI3K/Akt signaling Signaling by ERBB4 Role of LAT2/NTAL/LAB on calcium mobilization Constitutive PI3K/AKT Signaling in Cancer PI3K events in ERBB4 signaling Signaling by ERBB2 G alpha (q) signalling events Signaling by EGFR Signaling by Interleukins GPCR downstream signaling Downstream signal transduction Fc epsilon receptor (FCERI) signaling Signaling by EGFR in Cancer Interleukin-2 signaling PI3K/AKT Signaling in Cancer Platelet activation, signaling and aggregation Interleukin-3, 5 and GM-CSF signaling Adaptive Immune System G alpha (q) signalling events Costimulation by the CD28 family PIP3 activates AKT signaling Synthesis of PIPs at the plasma membrane G beta:gamma signalling through PI3Kgamma PI3K events in ERBB2 signaling Regulation of signaling by CBL Downstream signaling of activated FGFR G alpha (12/13) signalling events PI Metabolism Innate Immune System Signalling by NGF Cytokine Signaling in Immune system Signaling by Ligand-Responsive EGFR Variants in Cancer NGF signalling via TRKA from the plasma membrane Signaling by Overexpressed Wild-Type EGFR in Cancer Signaling by FGFR GPVI-mediated activation cascade Interleukin receptor SHC signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		42 interactors: AES AQP1 BEX2 BRD8 CBX8 CCDC112 CCHCR1 CDC73 CORO1A ESD FAM107A FAM161A FAM90A1 FMR1 IFT20 KANSL1 LATS1 LENG1 MRPL11 NDN NGFRAP1 PBX3 PIK3R3 POLL PPP1R18 PPP2R5D PSMB4 SH2D4A SPATC1L TCEANC ZBTB38 ZC2HC1C ZMAT2 ZNF124 ZNF20 ZNF230 ZNF410 ZNF417 ZNF572 ZNF581 ZNF587 ZSCAN26	38 interactors: ABCB6 AMBP AXL DARS DRAP1 DSN1 EGFR ERBB2 ERBB3 ESR1 FBN3 FGB FSD2 GC IGF1R INSR IRS1 IRS2 KARS KHDRBS1 KIAA1377 KLC2 L3MBTL3 LUC7L2 MBIP MICAL1 ORM1 PDGFRB PIK3CA PSME1 QARS RB1 RING1 SERF1A TEC TRIM54 TRMT2A VBP1
Entrez ID		123722	8503
HPRD ID		17291	05831
Ensembl ID		ENSG00000186628	ENSG00000117461
Uniprot IDs		A1L4K1 B7ZM02 B7ZM05	F6TDL0 Q8N381 Q92569
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Wnt Signaling Pathway Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Cellular Process Neurotrophin Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Cellular Metabolic Process Histone Ubiquitination Negative Regulation Of Canonical Wnt Signaling Pathway Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Posterior Compartment Specification Anterior Compartment Pattern Formation Opsin Transport Histone Modification Histone H4 Acetylation Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Wnt Signaling Pathway Carbon Dioxide Transmembrane Transport Corticotropin Secretion Early Endosome To Recycling Endosome Transport Establishment Or Maintenance Of Actin Cytoskeleton Polarity Respiratory Gaseous Exchange Negative Regulation Of Cellular Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Uropod Organization Metanephric Proximal Convoluted Tubule Development Nitric Oxide Transport Cellular Response To Mercury Ion Formaldehyde Catabolic Process	Phosphatidylinositol-mediated Signaling Regulation Of Phosphorylation Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Fc-epsilon Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Fc Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Innate Immune Response Immune System Process Cellular Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Phosphatidylinositol 3-kinase Signaling Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To Hormone Regulation Of Protein Kinase Activity Regulation Of Catalytic Activity Negative Regulation Of Cell Death Cellular Response To Hormone Stimulus Positive Regulation Of Signal Transduction Wound Healing Positive Regulation Of Cell Cycle Regulation Of Protein Metabolic Process Immune Response Regulation Of Immune System Process Regulation Of MAPK Cascade Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Phosphorylation Defense Response Organ Development Negative Regulation Of Signal Transduction Immune Response-regulating Signaling Pathway Positive Regulation Of Mitotic Nuclear Division Regulation Of Signaling Response To Wounding Protein Autophosphorylation Regulation Of Apoptotic Process Regulation Of Signal Transduction Negative Regulation Of Signaling Peptidyl-amino Acid Modification
Tagcloud ?			akt carcinogenesis diagnostic downregulated elucidating hcc hepatocellular insights invasion inversely investigations lead malignancy markedly micrornas migration mir mirnas mtor negatively phosphoinositide regulating repressing strategies suppressed suppression taken tissues underlying
Tagcloud (Difference) ?			akt carcinogenesis diagnostic downregulated elucidating hcc hepatocellular insights invasion inversely investigations lead malignancy markedly micrornas migration mir mirnas mtor negatively phosphoinositide regulating repressing strategies suppressed suppression taken tissues underlying
Tagcloud (Intersection) ?