FSD2 and FMR1

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid, two hybrid)

		FSD2	FMR1
Gene Name		fibronectin type III and SPRY domain containing 2	fragile X mental retardation 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleoplasm Nucleolus Cytoplasm MRNA Cap Binding Complex Microtubule Cytoplasmic Stress Granule Membrane Cytoplasmic Ribonucleoprotein Granule Polysomal Ribosome Dendritic Spine Dendritic Shaft Cell Body Synapse Neuronal Ribonucleoprotein Granule
	Molecular Function		RNA Binding MRNA Binding Protein Binding Microtubule Binding Poly(A) RNA Binding
	Biological Process		Central Nervous System Development Negative Regulation Of Translation Negative Regulation Of Translational Initiation MRNA Transport
Pathways
Drugs
Diseases
GWAS			Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956)
Protein-Protein Interactions		42 interactors: AES AQP1 BEX2 BRD8 CBX8 CCDC112 CCHCR1 CDC73 CORO1A ESD FAM107A FAM161A FAM90A1 FMR1 IFT20 KANSL1 LATS1 LENG1 MRPL11 NDN NGFRAP1 PBX3 PIK3R3 POLL PPP1R18 PPP2R5D PSMB4 SH2D4A SPATC1L TCEANC ZBTB38 ZC2HC1C ZMAT2 ZNF124 ZNF20 ZNF230 ZNF410 ZNF417 ZNF572 ZNF581 ZNF587 ZSCAN26	15 interactors: CYFIP1 CYFIP2 FSD2 FXR1 FXR2 INCA1 MEOX1 NCL NUFIP1 NUFIP2 RANBP9 SPAG5 STAU1 UBE2I YBX1
Entrez ID		123722	2332
HPRD ID		17291	02398
Ensembl ID		ENSG00000186628	ENSG00000102081
Uniprot IDs		A1L4K1 B7ZM02 B7ZM05	G3V0J0 G8JL90 G8JLE9 Q06787 Q8IXW7 R9WQY1
PDB IDs			2BKD 2FMR 2LA5 2QND
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Wnt Signaling Pathway Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Cellular Process Neurotrophin Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Cellular Metabolic Process Histone Ubiquitination Negative Regulation Of Canonical Wnt Signaling Pathway Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport Posterior Compartment Specification Anterior Compartment Pattern Formation Opsin Transport Histone Modification Histone H4 Acetylation Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Wnt Signaling Pathway Carbon Dioxide Transmembrane Transport Corticotropin Secretion Early Endosome To Recycling Endosome Transport Establishment Or Maintenance Of Actin Cytoskeleton Polarity Respiratory Gaseous Exchange Negative Regulation Of Cellular Metabolic Process Neurotrophin TRK Receptor Signaling Pathway Uropod Organization Metanephric Proximal Convoluted Tubule Development Nitric Oxide Transport Cellular Response To Mercury Ion Formaldehyde Catabolic Process	Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Translation Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Positive Regulation By Virus Of Viral Protein Levels In Host Cell Box C/D SnoRNP Assembly Posttranscriptional Regulation Of Gene Expression Regulation Of Cellular Process Sclerotome Development CRD-mediated MRNA Stabilization Somite Specification Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Actin Nucleation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase I Promoter Intracellular MRNA Localization Chromosome Segregation Positive Regulation Of Macromolecule Biosynthetic Process Hematopoietic Stem Cell Differentiation Positive Regulation Of Gene Expression Regulation Of Gene Expression
Tagcloud ?			17beta cav1 caveolae caveolin cgg cingulate copyright coupling demonstration electrophysiological eralpha facilitation fear fmrp fragile fxs glua1 inherited interacted ko plasticity potentiation raft recording rescued reserved retardation rights shrna
Tagcloud (Difference) ?			17beta cav1 caveolae caveolin cgg cingulate copyright coupling demonstration electrophysiological eralpha facilitation fear fmrp fragile fxs glua1 inherited interacted ko plasticity potentiation raft recording rescued reserved retardation rights shrna
Tagcloud (Intersection) ?