FSD2 and CORO1A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		FSD2	CORO1A
Description		fibronectin type III and SPRY domain containing 2	coronin 1A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Sarcoplasmic Reticulum Perinuclear Region Of Cytoplasm	Immunological Synapse Phagocytic Cup Nucleus Cytoplasm Early Endosome Cytosol Cytoskeleton Actin Filament Plasma Membrane Cell-cell Junction Cell Cortex Actin Cytoskeleton Membrane Lamellipodium Axon Phagocytic Vesicle Membrane Cortical Actin Cytoskeleton Cell Leading Edge Cytoplasmic Vesicle Protein-containing Complex Synapse Phagocytic Vesicle Extracellular Exosome Glutamatergic Synapse
	Molecular Function	Protein Binding	RNA Binding Actin Binding Actin Monomer Binding Protein Binding Cytoskeletal Protein Binding Myosin Heavy Chain Binding Identical Protein Binding Protein Homodimerization Activity Phosphatidylinositol 3-kinase Binding Actin Filament Binding
	Biological Process		Immunological Synapse Formation Phagolysosome Assembly Calcium Ion Transport Vesicle Fusion Phagocytosis Actin Filament Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Cell Shape Epithelial Cell Migration Cell Migration Actin Cytoskeleton Organization Leukocyte Chemotaxis Regulation Of Actin Filament Polymerization Negative Regulation Of Vesicle Fusion Cell-substrate Adhesion Uropod Organization Regulation Of Actin Cytoskeleton Organization Response To Cytokine Nerve Growth Factor Signaling Pathway T Cell Proliferation Positive Regulation Of T Cell Proliferation T Cell Activation T Cell Homeostasis Natural Killer Cell Degranulation Negative Regulation Of Neuron Apoptotic Process Innate Immune Response Homeostasis Of Number Of Cells Within A Tissue Positive Regulation Of T Cell Activation Positive Chemotaxis Negative Regulation Of Actin Nucleation Negative Regulation Of Cellular Component Organization Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Neuron Apoptotic Process Establishment Of Localization In Cell Early Endosome To Recycling Endosome Transport Cellular Response To Interleukin-4 T Cell Migration Thymocyte Migration Positive Regulation Of T Cell Migration
Pathways			Prevention of phagosomal-lysosomal fusion
Drugs
Diseases
GWAS		HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Tourette syndrome ( 30818990)	Brain morphology (MOSTest) ( 32665545) Hodgkin's lymphoma ( 30194254) Tonsillectomy ( 27182965 28928442)
Interacting Genes		93 interacting genes: AQP1 ARFIP2 ATF7IP2 ATG14 ATXN7L2 BEX2 BEX3 BRD8 C1orf216 CAMSAP3 CBX8 CCDC112 CCDC120 CCDC146 CCDC187 CCHCR1 CDC73 CDK18 CORO1A CTAG1A CTAG1B CWF19L2 DCX DTNB ENKD1 EXOC3 FAM107A FAM110A FAM161A FAM50B FAM90A1 FARS2 FMR1 HDAC4 HGS IFT20 KANSL1 KLHL40 LATS1 LENG1 LNX1 MCRS1 MID2 MRPL11 MYBPC2 NDN OIP5 OXNAD1 PBX3 PIK3R3 PNMA5 POLL PPP1R18 PPP2R5D PRPF18 PRPF31 PSMB4 RCOR3 RNF8 SCNM1 SH2D4A SMARCE1 SNAPIN SPATC1L TCEANC THAP7 TLE5 TSGA10IP TTC23 UBTFL1 VEZF1 ZBTB38 ZC2HC1C ZMAT2 ZNF124 ZNF20 ZNF230 ZNF35 ZNF408 ZNF410 ZNF417 ZNF490 ZNF572 ZNF580 ZNF581 ZNF587 ZNF648 ZNF76 ZNF774 ZNF777 ZNF835 ZNF837 ZSCAN26	21 interacting genes: ACTB CEBPA FHL3 FSD2 FXR1 GIT2 GOLGA2 IFT20 LMO2 MAGEA11 MAGOH NCF4 POLR1C POT1 SMAD3 SMARCD1 SPATA20 STAT3 TAB1 THBS1 YTHDC1
Entrez ID		123722	11151
HPRD ID		17291	05414
Ensembl ID		ENSG00000186628	ENSG00000102879
Uniprot IDs		A1L4K1 B7ZM05	P31146
PDB IDs
Enriched GO Terms of Interacting Partners?		Zinc Ion Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleus Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Gene Expression Metal Ion Binding Regulation Of Macromolecule Biosynthetic Process Identical Protein Binding Regulation Of Metabolic Process Centriole Microtubule Anchoring Microtubule Binding	Positive Regulation Of Biosynthetic Process Brahma Complex NBAF Complex RSC-type Complex NpBAF Complex GBAF Complex Positive Regulation Of Macromolecule Biosynthetic Process Transcription By RNA Polymerase I Chromatin DNA Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Interleukin-6-mediated Signaling Pathway DNA-binding Transcription Factor Binding Osteoblast Development DEAD/H-box RNA Helicase Binding Nuclear Glucocorticoid Receptor Binding Transcription Regulator Complex Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transforming Growth Factor Beta Production Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Nucleotide-excision Repair Negative Regulation Of Developmental Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Double-strand Break Repair Nucleoplasm Nuclear Matrix SWI/SNF Complex Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Developmental Process Positive Regulation Of Cell Differentiation Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macrophage Activation Positive Regulation Of Gene Expression Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process BHLH Transcription Factor Binding Positive Regulation Of Extracellular Matrix Organization Post-transcriptional Regulation Of Gene Expression Regulation Of MRNA Metabolic Process MRNA Transport RNA Transport Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing Positive Regulation Of Metabolic Process Regulation Of G0 To G1 Transition Regulation Of Multicellular Organismal Development Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Differentiation Positive Regulation Of Cell Activation Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B
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