EVI5 and FAM161A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EVI5	FAM161A
Description		ecotropic viral integration site 5	FAM161 centrosomal protein A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Spindle Cytosol Cytoskeleton	Astral Microtubule Photoreceptor Inner Segment Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Centriole Cytosol Cytoskeleton Spindle Microtubule Cilium Photoreceptor Connecting Cilium Ciliary Basal Body Cell Projection Mitotic Spindle Mitotic Spindle Pole
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Protein Binding Microtubule Binding Identical Protein Binding
	Biological Process	Retrograde Transport, Endosome To Golgi Positive Regulation Of GTPase Activity Cell Division Regulation Of Cilium Assembly	Visual Perception Cell Projection Organization Cilium Organization Cilium Assembly
Pathways
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Apolipoprotein B levels ( 32203549) Asthma or allergic disease (pleiotropy) ( 29785011) Body fat percentage and LDL-C (pairwise) ( 33619380) Cholesterol, total ( 25961943 24097068 20686565) Epstein Barr virus nuclear antigen 1 IgG levels or multiple sclerosis ( 26819262) LDL cholesterol ( 25961943 30275531) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 33339817 32154731) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Multiple sclerosis ( 19525955 31604244 21833088 24076602 27386562) Systemic lupus erythematosus ( 28714469) Total cholesterol levels ( 30275531 28334899 33339817)	Atrial fibrillation ( 29892015) Erectile dysfunction ( 30583798) Systemic lupus erythematosus ( 28714469)
Interacting Genes		21 interacting genes: ARL4A AURKB BIRC5 CCDC185 CEP19 CSNK1D ELOA FAM161A FBXO5 IMP3 INCENP LENG1 LMO1 MB21D2 MCRS1 MORF4L2 PRPF31 STX3 TCEANC TNFAIP8L1 ZNF446	139 interacting genes: AQP1 AXIN2 BACH2 BEGAIN BEND3 BEND5 BICD2 BRCA1 CADPS CALCOCO1 CALCOCO2 CARD9 CBY2 CCDC102B CCDC125 CCDC13 CCDC136 CCDC185 CCDC33 CCDC57 CCDC88B CCNC CCNDBP1 CDR2 CDR2L CEP44 CEP57L1 CEP63 CEP70 CEP72 CTNNA3 DHX32 DOCK8 DRC4 DVL2 EHMT2 EVI5 FAM9B FSD2 FXR1 GOLGA2 GOLGA6L9 GPBP1 GPRASP3 GRIPAP1 HEXIM2 HMBOX1 HOOK1 HOOK2 IKZF1 INO80E JRK KANK2 KASH5 KAT5 KDM1A KIAA0753 KIAA1328 KIFC3 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-3 KRTAP2-4 KRTAP5-7 KRTAP5-9 LDOC1 LMNA LURAP1L LZTS1 LZTS2 MAGEA11 MCC MCM6 MDFI MID2 MIPOL1 MKRN1 MTCL2 MTUS2 NECAB2 NINL NUTM1 OSBPL3 PDE4DIP PHC2 PIBF1 PICK1 PLEKHG4 PNMA1 PNMA2 POC5 PPFIA1 PPM1F PPP2R3C PRKAR1B QARS1 RINT1 ROPN1 RUBCN RUNDC3A SCNM1 SMARCD1 SSX2IP STX11 SYCE1 TAX1BP1 TBC1D1 TFIP11 TMCC2 TNIP1 TNIP3 TRAF1 TRAF2 TRIB3 TRIM15 TRIM27 TRIM37 TRIM41 TRIM54 TRIM69 TSGA10 TXLNB VIM VPS52 ZBTB1 ZBTB14 ZBTB43 ZBTB8A ZIM2 ZNF24 ZNF250 ZNF276 ZNF426 ZNF526 ZNF792 ZRANB1 ZSCAN12
Entrez ID		7813	84140
HPRD ID		04249	18996
Ensembl ID		ENSG00000067208	ENSG00000170264
Uniprot IDs		A0A804HIC4 A0A9L9PXE3 A0A9L9PXL1 A0A9L9PYE8 O60447 Q59FE7	Q3B820
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Chromosome Passenger Complex Spindle Assembly Spindle Microtubule Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Mitotic Spindle Midzone Assembly Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Spindle Midzone Assembly Positive Regulation Of Mitotic Cytokinesis Regulation Of Metaphase Plate Congression Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Sister Chromatid Separation Spindle Organization Positive Regulation Of Cell Cycle Checkpoint Regulation Of Chromosome Separation Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Nucleoplasm Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Chromosome Segregation Regulation Of Sister Chromatid Segregation Spindle Positive Regulation Of Chromosome Separation Regulation Of Chromosome Organization Microtubule Cytoskeleton Organization Regulation Of Mitotic Nuclear Division Organelle Assembly Membraneless Organelle Assembly Regulation Of Chromosome Segregation Positive Regulation Of Cytokinesis Mitotic Spindle Assembly Regulation Of Nuclear Division Chromosome, Centromeric Region Kinetochore Mitotic Cytokinesis Chromocenter Negative Regulation Of Chromosome Organization Regulation Of Cytokinesis Positive Regulation Of Cell Division Mitotic Spindle Organization Cytoskeleton-dependent Cytokinesis Cytoskeleton Positive Regulation Of Cell Cycle Process Microtubule-based Process Spindle Midzone Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Cell Cycle Mitotic Cell Cycle	Protein Binding Microtubule-based Process Identical Protein Binding Centrosome Microtubule Organizing Center Organization Microtubule Cytoskeleton Organization Cytoskeleton Intermediate Filament Centriole Replication Cytoplasm Centrosome Cycle Centriole Assembly Cytoskeleton Organization Microtubule Binding Cytoplasmic Microtubule Organization Response To Muramyl Dipeptide Microtubule Organelle Organization Negative Regulation Of RNA Metabolic Process Cellular Response To Muramyl Dipeptide Dynein Light Intermediate Chain Binding Zinc Ion Binding Regulation Of Organelle Organization Membraneless Organelle Assembly Negative Regulation Of Nucleobase-containing Compound Metabolic Process Centriolar Satellite Keratin Filament Cytosol Microtubule Organizing Center Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Organelle Assembly Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Suppression Of Viral Release By Host Centriole Negative Regulation Of Fatty Acid Biosynthetic Process Transcription Coactivator Activity Nuclear Pore Localization FHF Complex Ubiquitin Protein Ligase Activity Protein Localization To Cytoskeleton Nucleus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?