EVI5 and TCEANC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EVI5	TCEANC
Description		ecotropic viral integration site 5	transcription elongation factor A N-terminal and central domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Spindle Cytosol Cytoskeleton	Nucleus
	Molecular Function	GTPase Activator Activity Protein Binding Small GTPase Binding	Protein Binding
	Biological Process	Retrograde Transport, Endosome To Golgi Positive Regulation Of GTPase Activity Cell Division Regulation Of Cilium Assembly	DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Apolipoprotein B levels ( 32203549) Asthma or allergic disease (pleiotropy) ( 29785011) Body fat percentage and LDL-C (pairwise) ( 33619380) Cholesterol, total ( 25961943 24097068 20686565) Epstein Barr virus nuclear antigen 1 IgG levels or multiple sclerosis ( 26819262) LDL cholesterol ( 25961943 30275531) LDL cholesterol levels ( 32203549) Low density lipoprotein cholesterol levels ( 33339817 32154731) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Multiple sclerosis ( 19525955 31604244 21833088 24076602 27386562) Systemic lupus erythematosus ( 28714469) Total cholesterol levels ( 30275531 28334899 33339817)
Interacting Genes		21 interacting genes: ARL4A AURKB BIRC5 CCDC185 CEP19 CSNK1D ELOA FAM161A FBXO5 IMP3 INCENP LENG1 LMO1 MB21D2 MCRS1 MORF4L2 PRPF31 STX3 TCEANC TNFAIP8L1 ZNF446	140 interacting genes: ADARB1 AKAP9 ANAPC11 APP ATXN1 AXIN2 BICD2 BRCA1 C1QTNF2 C8orf34 CARD9 CBY2 CCDC102B CCDC136 CCDC138 CCDC33 CCDC85B CCNC CDR2L CEP70 CEP76 CRACR2B CREB3L3 CSRNP1 CTAG1A CTAG1B CYSRT1 DAB1 DISC1 DMAP1 DTX3 DVL3 DYNLT1 EVI5 FAM217B FAM9B FANCG FBXO25 FCHO1 FSD2 GOLGA2 GOLGA6L9 HES7 HIP1 HMBOX1 HOMEZ HOOK2 IGF1 IKBKG IKZF2 IKZF3 KATNBL1 KCTD6 KCTD7 KIAA1958 KIF16B KIFC3 KLHL12 KRT31 KRT35 KRT40 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP4-2 KRTAP5-9 L3MBTL3 LDOC1 LHX2 LHX3 LIN7B LMNA LSM14B LURAP1 MAGEA11 MCC MCIDAS MDFI MEOX1 MEOX2 MID1 MID2 MTUS2 MYF5 MYLIP NAB2 NECAB1 NEDD4 NINL OBI1 OOEP OSBPL3 PICK1 PLEKHF2 PNMA1 PNMA5 PXN RAD54B RNF41 RUBCN SIPA1L2 SORBS3 SSNA1 STRN3 STX1A STX4 TARBP2 TCP10L THAP1 TLE5 TMCO2 TNIP1 TNIP3 TRAF2 TRIM23 TRIM27 TRIM32 TRIM35 TRIM37 TRIM41 TRIM54 UBXN11 USH1G USHBP1 VAC14 VBP1 VPS52 YWHAE ZBTB14 ZBTB39 ZBTB9 ZFYVE26 ZKSCAN7 ZNF276 ZNF655 ZNF670 ZNF688 ZNF837 ZRANB1
Entrez ID		7813	170082
HPRD ID		04249	19501
Ensembl ID		ENSG00000067208	ENSG00000176896
Uniprot IDs		A0A804HIC4 A0A9L9PXE3 A0A9L9PXL1 A0A9L9PYE8 O60447 Q59FE7	A8K5F6 B4DG85 Q8N8B7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Chromosome Passenger Complex Spindle Assembly Spindle Microtubule Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore Mitotic Spindle Midzone Assembly Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Spindle Midzone Assembly Positive Regulation Of Mitotic Cytokinesis Regulation Of Metaphase Plate Congression Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Sister Chromatid Separation Spindle Organization Positive Regulation Of Cell Cycle Checkpoint Regulation Of Chromosome Separation Regulation Of Attachment Of Spindle Microtubules To Kinetochore Positive Regulation Of Mitotic Sister Chromatid Separation Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Nucleoplasm Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Chromosome Segregation Regulation Of Sister Chromatid Segregation Spindle Positive Regulation Of Chromosome Separation Regulation Of Chromosome Organization Microtubule Cytoskeleton Organization Regulation Of Mitotic Nuclear Division Organelle Assembly Membraneless Organelle Assembly Regulation Of Chromosome Segregation Positive Regulation Of Cytokinesis Mitotic Spindle Assembly Regulation Of Nuclear Division Chromosome, Centromeric Region Kinetochore Mitotic Cytokinesis Chromocenter Negative Regulation Of Chromosome Organization Regulation Of Cytokinesis Positive Regulation Of Cell Division Mitotic Spindle Organization Cytoskeleton-dependent Cytokinesis Cytoskeleton Positive Regulation Of Cell Cycle Process Microtubule-based Process Spindle Midzone Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Cell Cycle Mitotic Cell Cycle	Identical Protein Binding Protein Binding Ubiquitin Protein Ligase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Cytosol Intermediate Filament Post-translational Protein Modification Ubiquitin-protein Transferase Activity Keratin Filament Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cytoskeleton Regulation Of Transcription By RNA Polymerase II Microtubule-based Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Zinc Ion Binding Suppression Of Viral Release By Host Regulation Of Viral Transcription Regulation Of Primary Metabolic Process Centrosome Cytoplasm Microtubule Binding Protein Monoubiquitination Regulation Of Organelle Organization Microtubule Regulation Of Cellular Component Organization Regulation Of Macromolecule Metabolic Process Protein Autoubiquitination Negative Regulation Of Viral Transcription Microtubule Cytoskeleton Organization Protein K63-linked Ubiquitination Nucleus Regulation Of Cytoskeleton Organization Enzyme Binding Signaling Adaptor Activity Protein Polyubiquitination Regulation Of Metabolic Process Intracellular Transport Somite Specification Response To Muramyl Dipeptide Establishment Of Localization In Cell Positive Regulation Of Catabolic Process Regulation Of Macromolecule Biosynthetic Process
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