RPH3AL and RIMS2

Number of citations of the paper that reports this interaction (PMID 10707984)
40

Data Source:
HPRD (in vivo, two hybrid)

		RPH3AL	RIMS2
Gene Name		rabphilin 3A-like (without C2 domains)	regulating synaptic membrane exocytosis 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane	Cell Junction Presynaptic Membrane Presynaptic Active Zone Extracellular Vesicular Exosome
	Molecular Function	Cytoskeletal Protein Binding Rab GTPase Binding LIM Domain Binding Metal Ion Binding	Protein Binding Rab GTPase Binding Ion Channel Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Response To Drug Glucose Homeostasis Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Secretion	Intracellular Protein Transport Positive Regulation Of Gene Expression Calcium Ion-dependent Exocytosis Regulation Of Exocytosis CAMP-mediated Signaling Insulin Secretion Regulation Of Membrane Potential Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Pathways
Drugs
Diseases
GWAS		AIDS progression ( 21502085)
Protein-Protein Interactions		13 interactors: MID2 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 TCEA3 UNC13B ZYX	12 interactors: ABCA1 CACNA1S RAB27A RAB3A RAB3B RAB3C RAB3D RAB8A RABAC1 RAPGEF4 RPH3AL YWHAH
Entrez ID		9501	9699
HPRD ID		05345	09436
Ensembl ID		ENSG00000181031
Uniprot IDs		A8K7D5 Q9UNE2	Q9UQ26
PDB IDs			1V27 1WFG
Enriched GO Terms of Interacting Partners?		Vesicle Docking Involved In Exocytosis Regulation Of Exocytosis Vesicle Docking Membrane Docking Protein Secretion Rab Protein Signal Transduction Exocytosis Establishment Of Vesicle Localization Vesicle Localization Regulation Of Vesicle-mediated Transport Regulation Of Secretion Neurotransmitter Secretion Synaptic Vesicle Transport Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Levels Secretion By Cell Neurotransmitter Transport Establishment Of Organelle Localization Cell-cell Signaling Synaptic Transmission Secretion Regulation Of Cellular Localization Ras Protein Signal Transduction Organelle Localization Cellular Protein Localization Positive Regulation Of Exocytosis Cellular Localization Protein Localization Intracellular Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Positive Regulation Of Secretion Small GTPase Mediated Signal Transduction Regulation Of Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Positive Regulation Of Transport Intracellular Signal Transduction Establishment Of Localization In Cell Positive Regulation Of Regulated Secretory Pathway Protein Transport Intracellular Transport Regulation Of Synaptic Transmission Peptidyl-cysteine Methylation Regulation Of Regulated Secretory Pathway Multivesicular Body Sorting Pathway Regulation Of Synaptic Plasticity Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Regulation Of Neurotransmitter Secretion Signaling Cell Communication	Protein Secretion Regulation Of Exocytosis Secretion By Cell Rab Protein Signal Transduction Vesicle Docking Involved In Exocytosis Exocytosis Secretion Regulation Of Vesicle-mediated Transport Vesicle Docking Membrane Docking Synaptic Vesicle Transport Protein Transport Establishment Of Protein Localization Synaptic Vesicle Exocytosis Regulation Of Cellular Localization Regulation Of Secretion Protein Localization Establishment Of Vesicle Localization Vesicle Localization Establishment Of Localization In Cell Ras Protein Signal Transduction Vesicle-mediated Transport Intracellular Protein Transport Neurotransmitter Secretion Intracellular Transport Cellular Localization Small GTPase Mediated Signal Transduction Establishment Of Organelle Localization Regulation Of Neurotransmitter Levels Neurotransmitter Transport Positive Regulation Of Transport Organelle Localization Cellular Protein Localization Cell-cell Signaling Transport Positive Regulation Of Regulated Secretory Pathway Synaptic Transmission Intracellular Signal Transduction Peptidyl-cysteine Methylation Regulation Of Regulated Secretory Pathway Positive Regulation Of Exocytosis Regulation Of Synaptic Transmission Response To Stimulus Positive Regulation Of Secretion Endomembrane System Organization Signal Transduction Regulation Of Synaptic Plasticity Signaling Cell Communication Vesicle Organization
Tagcloud ?		artificial au bac breakpoints cafe cals cyto deletions dieker dysmorphisms emerges ends facial fosmid frames haploinsufficiency lait mdcr metrnl miller p1 pac preserved probes retardation sole spots subcloned unrevealed
Tagcloud (Difference) ?		artificial au bac breakpoints cafe cals cyto deletions dieker dysmorphisms emerges ends facial fosmid frames haploinsufficiency lait mdcr metrnl miller p1 pac preserved probes retardation sole spots subcloned unrevealed
Tagcloud (Intersection) ?