RPH3AL and RAB3D

Number of citations of the paper that reports this interaction (PMID 12578829)
33

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		RPH3AL	RAB3D
Gene Name		rabphilin 3A-like (without C2 domains)	RAB3D, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane	Mitochondrion Endosome Plasma Membrane Synaptic Vesicle Transport Vesicle Secretory Granule Membrane Zymogen Granule Extracellular Vesicular Exosome
	Molecular Function	Cytoskeletal Protein Binding Rab GTPase Binding LIM Domain Binding Metal Ion Binding	GTPase Activity GTP Binding GDP Binding Myosin V Binding GTPase Binding
	Biological Process	Intracellular Protein Transport Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Response To Drug Glucose Homeostasis Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Secretion	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Synaptic Vesicle Exocytosis Regulation Of Exocytosis Peptidyl-cysteine Methylation Rab Protein Signal Transduction Protein Localization To Plasma Membrane Positive Regulation Of Regulated Secretory Pathway
Pathways
Drugs
Diseases
GWAS		AIDS progression ( 21502085)	HDL cholesterol ( 23505323)
Protein-Protein Interactions		13 interactors: MID2 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 TCEA3 UNC13B ZYX	12 interactors: AKT1 AKT2 AP1M2 APP CEP55 CHM CYP2C9 MAST1 RAB3IP RIMS2 RNF32 RPH3AL
Entrez ID		9501	9545
HPRD ID		05345	05070
Ensembl ID		ENSG00000181031	ENSG00000105514
Uniprot IDs		A8K7D5 Q9UNE2	O95716
PDB IDs			2GF9
Enriched GO Terms of Interacting Partners?		Vesicle Docking Involved In Exocytosis Regulation Of Exocytosis Vesicle Docking Membrane Docking Protein Secretion Rab Protein Signal Transduction Exocytosis Establishment Of Vesicle Localization Vesicle Localization Regulation Of Vesicle-mediated Transport Regulation Of Secretion Neurotransmitter Secretion Synaptic Vesicle Transport Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Levels Secretion By Cell Neurotransmitter Transport Establishment Of Organelle Localization Cell-cell Signaling Synaptic Transmission Secretion Regulation Of Cellular Localization Ras Protein Signal Transduction Organelle Localization Cellular Protein Localization Positive Regulation Of Exocytosis Cellular Localization Protein Localization Intracellular Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Positive Regulation Of Secretion Small GTPase Mediated Signal Transduction Regulation Of Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Positive Regulation Of Transport Intracellular Signal Transduction Establishment Of Localization In Cell Positive Regulation Of Regulated Secretory Pathway Protein Transport Intracellular Transport Regulation Of Synaptic Transmission Peptidyl-cysteine Methylation Regulation Of Regulated Secretory Pathway Multivesicular Body Sorting Pathway Regulation Of Synaptic Plasticity Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Regulation Of Neurotransmitter Secretion Signaling Cell Communication	Protein Localization Establishment Of Localization In Cell Cellular Protein Localization Establishment Of Protein Localization Intracellular Protein Transport Intracellular Transport Cellular Localization Protein Transport Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Peripheral Nervous System Myelin Maintenance Positive Regulation Of Glycogen Biosynthetic Process Membrane Organization Regulation Of Fatty Acid Beta-oxidation Protein Targeting Myelin Maintenance Mammary Gland Epithelial Cell Differentiation Negative Regulation Of Lipid Transport Glycogen Biosynthetic Process Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Regulation Of Fatty Acid Transport Positive Regulation Of Glucose Metabolic Process Myelination In Peripheral Nervous System Positive Regulation Of Glucose Import Cellular Polysaccharide Biosynthetic Process Regulation Of Glycogen Metabolic Process Schwann Cell Development Positive Regulation Of Glucose Transport Polysaccharide Biosynthetic Process Negative Regulation Of Ion Transmembrane Transport Regulation Of Translation Vesicle-mediated Transport Schwann Cell Differentiation Negative Regulation Of Transmembrane Transport Regulation Of Glucose Import Transport Regulation Of Lipid Catabolic Process Glycogen Metabolic Process Positive Regulation Of Catalytic Activity Exocytosis Glycogen Cell Differentiation Involved In Embryonic Placenta Development Protein Localization To Membrane Regulation Of Vesicle-mediated Transport Regulation Of Generation Of Precursor Metabolites And Energy Polysaccharide Metabolic Process Regulation Of Fatty Acid Metabolic Process Post-Golgi Vesicle-mediated Transport Regulation Of Glucose Transport Glial Cell Development Regulation Of Lipid Transport
Tagcloud ?		artificial au bac breakpoints cafe cals cyto deletions dieker dysmorphisms emerges ends facial fosmid frames haploinsufficiency lait mdcr metrnl miller p1 pac preserved probes retardation sole spots subcloned unrevealed	cease chief he4 imchief immortomice immortomouse imspem lineages mal2 metaplasia metaplasias metaplastic myelin nonpermissive owing oxyntic pepsinogen permissive preneoplastic proliferate reliance resemble secrete sole spasmolytic spem stomach tff2 transdifferentiation
Tagcloud (Difference) ?		artificial au bac breakpoints cafe cals cyto deletions dieker dysmorphisms emerges ends facial fosmid frames haploinsufficiency lait mdcr metrnl miller p1 pac preserved probes retardation spots subcloned unrevealed	cease chief he4 imchief immortomice immortomouse imspem lineages mal2 metaplasia metaplasias metaplastic myelin nonpermissive owing oxyntic pepsinogen permissive preneoplastic proliferate reliance resemble secrete spasmolytic spem stomach tff2 transdifferentiation
Tagcloud (Intersection) ?		sole