RPH3AL and RAB27B

Number of citations of the paper that reports this interaction (PMID 12578829)
33

Data Source:
HPRD (in vivo)

		RPH3AL	RAB27B
Gene Name		rabphilin 3A-like (without C2 domains)	RAB27B, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane	Golgi Stack Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	Cytoskeletal Protein Binding Rab GTPase Binding LIM Domain Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Response To Drug Glucose Homeostasis Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Secretion	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Melanosome Transport Rab Protein Signal Transduction Positive Regulation Of Exocytosis Multivesicular Body Sorting Pathway
Pathways
Drugs
Diseases
GWAS		AIDS progression ( 21502085)
Protein-Protein Interactions		13 interactors: MID2 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 TCEA3 UNC13B ZYX	8 interactors: DHPS MLPH RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D
Entrez ID		9501	5874
HPRD ID		05345	04846
Ensembl ID		ENSG00000181031	ENSG00000041353
Uniprot IDs		A8K7D5 Q9UNE2	O00194
PDB IDs			2F7S
Enriched GO Terms of Interacting Partners?		Vesicle Docking Involved In Exocytosis Regulation Of Exocytosis Vesicle Docking Membrane Docking Protein Secretion Rab Protein Signal Transduction Exocytosis Establishment Of Vesicle Localization Vesicle Localization Regulation Of Vesicle-mediated Transport Regulation Of Secretion Neurotransmitter Secretion Synaptic Vesicle Transport Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Levels Secretion By Cell Neurotransmitter Transport Establishment Of Organelle Localization Cell-cell Signaling Synaptic Transmission Secretion Regulation Of Cellular Localization Ras Protein Signal Transduction Organelle Localization Cellular Protein Localization Positive Regulation Of Exocytosis Cellular Localization Protein Localization Intracellular Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Positive Regulation Of Secretion Small GTPase Mediated Signal Transduction Regulation Of Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Positive Regulation Of Transport Intracellular Signal Transduction Establishment Of Localization In Cell Positive Regulation Of Regulated Secretory Pathway Protein Transport Intracellular Transport Regulation Of Synaptic Transmission Peptidyl-cysteine Methylation Regulation Of Regulated Secretory Pathway Multivesicular Body Sorting Pathway Regulation Of Synaptic Plasticity Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Regulation Of Neurotransmitter Secretion Signaling Cell Communication	Exocytosis Secretion By Cell Secretion Intracellular Protein Transport Establishment Of Localization In Cell Cellular Localization Cellular Protein Localization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Positive Regulation Of Secretion Protein Localization Regulation Of Exocytosis Regulation Of Secretion Positive Regulation Of Transport Transport Positive Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Deoxyhypusine Biosynthetic Process From Spermidine Granuloma Formation Spermidine Catabolic Process Multivesicular Body Sorting Pathway Peptidyl-lysine Modification To Peptidyl-hypusine Polyamine Catabolic Process Positive Regulation Of Protein Secretion Glucose Homeostasis Natural Killer Cell Degranulation Regulation Of Cellular Localization Chronic Inflammatory Response Positive Regulation Of Mucus Secretion Germinal Center Formation Positive Regulation Of Protein Transport Regulation Of Mucus Secretion Positive Regulation Of Regulated Secretory Pathway Regulation Of Protein Secretion Natural Killer Cell Activation Involved In Immune Response Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Regulation Of Mast Cell Degranulation Regulation Of Cell Activation Polyamine Metabolic Process Leukocyte Mediated Cytotoxicity Regulation Of Mast Cell Activation Melanocyte Differentiation Negative Regulation Of Insulin Secretion Regulation Of Regulated Secretory Pathway Melanosome Localization Leukocyte Degranulation Negative Regulation Of Peptide Secretion
Tagcloud ?		artificial au bac breakpoints cafe cals cyto deletions dieker dysmorphisms emerges ends facial fosmid frames haploinsufficiency lait mdcr metrnl miller p1 pac preserved probes retardation sole spots subcloned unrevealed	7d autonomous biogenesis contributed deficient dicer disrupt exosomal exosome exosomes foxp3 helper intercellular interference let mechanistic micrornas mirna mirnas providing requirement silencing suppress suppressing suppression th1 transferred treg
Tagcloud (Difference) ?		artificial au bac breakpoints cafe cals cyto deletions dieker dysmorphisms emerges ends facial fosmid frames haploinsufficiency lait mdcr metrnl miller p1 pac preserved probes retardation sole spots subcloned unrevealed	7d autonomous biogenesis contributed deficient dicer disrupt exosomal exosome exosomes foxp3 helper intercellular interference let mechanistic micrornas mirna mirnas providing requirement silencing suppress suppressing suppression th1 transferred treg
Tagcloud (Intersection) ?