RPH3AL and RAB3GAP1

Number of citations of the paper that reports this interaction (PMID 14593078)
9

Data Source:
BioGRID (pull down)

		RPH3AL	RAB3GAP1
Gene Name		rabphilin 3A-like (without C2 domains)	RAB3 GTPase activating protein subunit 1 (catalytic)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane	Cytoplasm Protein Complex Extracellular Vesicular Exosome Endoplasmic Reticulum Tubular Network
	Molecular Function	Cytoskeletal Protein Binding Rab GTPase Binding LIM Domain Binding Metal Ion Binding	Rab GTPase Activator Activity Rab Guanyl-nucleotide Exchange Factor Activity Rab GTPase Binding
	Biological Process	Intracellular Protein Transport Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Response To Drug Glucose Homeostasis Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Secretion	Brain Development Hypothalamus Development Positive Regulation Of Rab GTPase Activity Lipid Particle Organization Camera-type Eye Development Regulation Of GTPase Activity Regulation Of Short-term Neuronal Synaptic Plasticity Regulation Of Excitatory Postsynaptic Membrane Potential Face Morphogenesis Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization
Pathways
Drugs
Diseases
GWAS		AIDS progression ( 21502085)	Cholesterol, total ( 20686565) Corneal structure ( 21979947)
Protein-Protein Interactions		13 interactors: MID2 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 TCEA3 UNC13B ZYX	8 interactors: FEZ1 FEZ2 RAB22A RAB39A RAB39B RAB3GAP2 RPH3AL WDR7
Entrez ID		9501	22930
HPRD ID		05345	16002
Ensembl ID		ENSG00000181031	ENSG00000115839
Uniprot IDs		A8K7D5 Q9UNE2	B9A6J2 C9J837 Q15042
PDB IDs
Enriched GO Terms of Interacting Partners?		Vesicle Docking Involved In Exocytosis Regulation Of Exocytosis Vesicle Docking Membrane Docking Protein Secretion Rab Protein Signal Transduction Exocytosis Establishment Of Vesicle Localization Vesicle Localization Regulation Of Vesicle-mediated Transport Regulation Of Secretion Neurotransmitter Secretion Synaptic Vesicle Transport Synaptic Vesicle Exocytosis Regulation Of Neurotransmitter Levels Secretion By Cell Neurotransmitter Transport Establishment Of Organelle Localization Cell-cell Signaling Synaptic Transmission Secretion Regulation Of Cellular Localization Ras Protein Signal Transduction Organelle Localization Cellular Protein Localization Positive Regulation Of Exocytosis Cellular Localization Protein Localization Intracellular Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Positive Regulation Of Secretion Small GTPase Mediated Signal Transduction Regulation Of Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Positive Regulation Of Transport Intracellular Signal Transduction Establishment Of Localization In Cell Positive Regulation Of Regulated Secretory Pathway Protein Transport Intracellular Transport Regulation Of Synaptic Transmission Peptidyl-cysteine Methylation Regulation Of Regulated Secretory Pathway Multivesicular Body Sorting Pathway Regulation Of Synaptic Plasticity Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Regulation Of Neurotransmitter Secretion Signaling Cell Communication See more	Rab Protein Signal Transduction Intracellular Protein Transport Establishment Of Localization In Cell Cellular Localization Cellular Protein Localization Protein Transport Ras Protein Signal Transduction Establishment Of Protein Localization Intracellular Transport Protein Localization Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Regulation Of Vesicle Size Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Phagosome-lysosome Fusion Transport Phagosome Acidification Negative Regulation Of Macroautophagy Phagolysosome Assembly Establishment Of Mitochondrion Localization Intracellular PH Reduction Axon Guidance PH Reduction See more
Tagcloud ?		artificial au bac breakpoints cafe cals cyto deletions dieker dysmorphisms emerges ends facial fosmid frames haploinsufficiency lait mdcr metrnl miller p1 pac preserved probes retardation sole spots subcloned unrevealed	acidic adaptor anchored binds catalytic compartment consists envelope ergic etc execute ff ffat golgi gtpase heterodimer motif phenylalanines potently recruit reduces substitution tail traffic vap vesicle
Tagcloud (Difference) ?		artificial au bac breakpoints cafe cals cyto deletions dieker dysmorphisms emerges ends facial fosmid frames haploinsufficiency lait mdcr metrnl miller p1 pac preserved probes retardation sole spots subcloned unrevealed	acidic adaptor anchored binds catalytic compartment consists envelope ergic etc execute ff ffat golgi gtpase heterodimer motif phenylalanines potently recruit reduces substitution tail traffic vap vesicle
Tagcloud (Intersection) ?