LCP2 and SYK

  • Number of citations of the paper that reports this interaction (PMID 15388330)
  • 9
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro, two hybrid)

LCP2

SYK

Gene Name lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) spleen tyrosine kinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 39 interactors: APP BLNK CBL CD22 CLNK FXR2 FYB FYN GOLGA2 GRAP2 GRB2 HCK ITK LAT LCK LYN MAP4K1 NCK1 NCK2 PAG1 PIK3R1 PLCG1 PLCG2 PRAM1 PTPN6 PTPRC SH3GL2 SHB SHC1 STAM2 SYK TRAT1 TXK VAV1 VAV3 WAS YBX1 YWHAZ ZAP70 98 interactors: APP BLNK BTK CALM1 CBL CBLB CD19 CD22 CD3E CD72 CD79A CD79B CRKL CSF2RB CSF3R CTTN DBNL DUSP3 EGFR EPOR ERBB2 ERBB3 ERBB4 FCER1G FCGR1A FCGR2A FCGR3A FCRL3 FGR FYN GAB2 GRB2 HCLS1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC6 HDAC9 HNRNPU IL15RA IL2RB ITGB2 JAK1 LAT LAX1 LCK LCP2 LYN MAP4K1 MAPK3 MAPT MS4A2 NEDD4 NFAM1 PAG1 PIK3AP1 PIK3R1 PIK3R2 PLCG1 PLCG2 POU2AF1 PRKCA PRKD1 PTK2 PTK2B PTPN6 PXN RASA1 RPS10 RPS6KA1 RPS6KB1 RPS6KB2 SELPLG SH2B2 SH2D2A SH3BP2 SHC1 SIT1 SLA SLC4A1 SNCA SRC STAT1 STAT3 STAT5A TERF1 TLR4 TNFRSF1A TRAF6 TUBA1A TUBA4A TYROBP UBASH3B UBB USP25 VAV1 VAV2
Entrez ID 3937 6850
HPRD ID 03362 02514
Ensembl ID ENSG00000165025
Uniprot IDs Q13094 A8K4G2 P43405
PDB IDs 1H3H 1YWO 2EAP 2ROR 1A81 1CSY 1CSZ 1XBA 1XBB 1XBC 3BUW 3EMG 3FQE 3FQH 3FQS 3SRV 3TUB 3TUC 3TUD 3VF8 3VF9 4DFL 4DFN 4F4P 4FL1 4FL2 4FL3 4FYN 4FYO 4FZ6 4FZ7 4GFG
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aurkb  bub1b  ccnb1  cd247  cd3d  cd3g  cd8a  cdc20  cdca8  cenpa  cytoscape  dihydroxyfluorane  epstain  generank  hindering  itgb5  itk  kif2c  limma  lymphoblasts  mad2l1  nup37  pik3r3  plcg2  prkcq  rpa3  softwares  vav3  zap70 
belongs  bind  binds  blotting  coimmunoprecipitation  contribution  cytokine  domains  epo  epor  erythroid  erythropoietin  far  homology  individually  interaction  jak2  mediate  paper  participated  propose  recombinant  regulates  sh2  src  tandem  tyrosine  tyrosines  ut7 
Tagcloud (Difference) ?
aurkb  bub1b  ccnb1  cd247  cd3d  cd3g  cd8a  cdc20  cdca8  cenpa  cytoscape  dihydroxyfluorane  epstain  generank  hindering  itgb5  itk  kif2c  limma  lymphoblasts  mad2l1  nup37  pik3r3  plcg2  prkcq  rpa3  softwares  vav3  zap70 
belongs  bind  binds  blotting  coimmunoprecipitation  contribution  cytokine  domains  epo  epor  erythroid  erythropoietin  far  homology  individually  interaction  jak2  mediate  paper  participated  propose  recombinant  regulates  sh2  src  tandem  tyrosine  tyrosines  ut7 
Tagcloud (Intersection) ?