CAMLG and PGRMC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CAMLG	PGRMC1
Description		calcium modulating ligand	progesterone receptor membrane component 1
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex	Extracellular Region Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Amyloid-beta Binding Steroid Binding Protein Binding Lipid Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	B Cell Homeostasis Receptor Recycling Defense Response Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Insertion Into ER Membrane Protein Stabilization Tail-anchored Membrane Protein Insertion Into ER Membrane	Heme Biosynthetic Process Axon Guidance Memory Associative Learning Modification Of Synaptic Structure Positive Regulation Of Lipoprotein Transport Positive Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Synapse Organization
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Neutrophil degranulation
Drugs		Cyclosporine Voclosporin	Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS		Height ( 18391951)	Hodgkin's lymphoma ( 34216518)
Interacting Genes		21 interacting genes: ADIPOQ AGR2 BCL2L13 EGFR ETNK1 F11R GET1 HSP90B1 HSPA13 KCNE4 LAT LCN2 OCIAD1 PBXIP1 PGRMC1 PKHD1 PPIB TMEM31 TNFRSF13B TXNDC12 VWC2	20 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 LINC00632 MTNR1A PAM16 SCAP SGTB TMEM213 ZNF71
Entrez ID		819	10857
HPRD ID		03073	02338
Ensembl ID		ENSG00000164615	ENSG00000101856
Uniprot IDs		P49069	O00264 Q6IB11
PDB IDs		6SO5 8CR1	4X8Y
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Localization Within Membrane Positive Regulation Of Protein Localization To Plasma Membrane Endoplasmic Reticulum Chaperone Complex Positive Regulation Of Protein Localization To Cell Periphery Positive Regulation Of Protein Localization To Membrane Protein Localization To Cell Periphery Digestive Tract Morphogenesis Protein-containing Complex Smooth Endoplasmic Reticulum Regulation Of Protein Localization To Plasma Membrane Regulation Of Cellular Localization Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Protein Localization To Membrane	GET Complex
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