CAMLG and TXNDC12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CAMLG	TXNDC12
Description		calcium modulating ligand	thioredoxin domain containing 12
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane GET Complex	Endoplasmic Reticulum Endoplasmic Reticulum Lumen
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	Protein Binding Protein-disulfide Reductase Activity Oxidoreductase Activity Protein-disulfide Reductase (glutathione) Activity
	Biological Process	B Cell Homeostasis Receptor Recycling Defense Response Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Negative Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Insertion Into ER Membrane Protein Stabilization Tail-anchored Membrane Protein Insertion Into ER Membrane	Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways		Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs		Cyclosporine Voclosporin
Diseases
GWAS		Height ( 18391951)
Interacting Genes		21 interacting genes: ADIPOQ AGR2 BCL2L13 EGFR ETNK1 F11R GET1 HSP90B1 HSPA13 KCNE4 LAT LCN2 OCIAD1 PBXIP1 PGRMC1 PKHD1 PPIB TMEM31 TNFRSF13B TXNDC12 VWC2	9 interacting genes: CAMLG DPF2 FKBP7 KLHL2 SGTA SGTB UBQLN1 UBQLN2 ZDHHC17
Entrez ID		819	51060
HPRD ID		03073	11633
Ensembl ID		ENSG00000164615	ENSG00000117862
Uniprot IDs		P49069	O95881
PDB IDs		6SO5 8CR1	1SEN 2K8V
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Localization Within Membrane Positive Regulation Of Protein Localization To Plasma Membrane Endoplasmic Reticulum Chaperone Complex Positive Regulation Of Protein Localization To Cell Periphery Positive Regulation Of Protein Localization To Membrane Protein Localization To Cell Periphery Digestive Tract Morphogenesis Protein-containing Complex Smooth Endoplasmic Reticulum Regulation Of Protein Localization To Plasma Membrane Regulation Of Cellular Localization Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Protein Localization To Membrane	TRC Complex Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Proteasomal Protein Catabolic Process Regulation Of Response To Endoplasmic Reticulum Stress Post-translational Protein Targeting To Endoplasmic Reticulum Membrane ERAD Pathway Regulation Of Protein Catabolic Process Regulation Of Proteolysis Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Proteasomal Protein Catabolic Process Identical Protein Binding Protein Insertion Into ER Membrane Regulation Of Cellular Response To Stress Protein Targeting To ER Establishment Of Protein Localization To Membrane Positive Regulation Of Proteolysis Establishment Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of Protein Catabolic Process Polyubiquitin Modification-dependent Protein Binding Protein Catabolic Process Response To Endoplasmic Reticulum Stress Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Myeloid Progenitor Cell Differentiation Perforant Pathway To Dendrate Granule Cell Synapse Negative Regulation Of Store-operated Calcium Channel Activity Protein Insertion Into Membrane Protein Targeting To Membrane Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Autophagosome Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Negative Regulation Of G Protein-coupled Receptor Internalization Autophagosome Assembly Autophagosome Organization Macromolecule Catabolic Process GET Complex Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Protein Catabolic Process Localization Within Membrane Regulation Of Myeloid Progenitor Cell Differentiation Histone H3K14ac Reader Activity BAT3 Complex Binding Proteolysis Negative Regulation Of Clathrin-dependent Endocytosis
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