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UBE2D3 and TUBA1A
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
0
Data Source:
BioGRID
(two hybrid)
UBE2D3
TUBA1A
Description
ubiquitin conjugating enzyme E2 D3
tubulin alpha 1a
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Endosome
Cytosol
Plasma Membrane
Endosome Membrane
Membrane
Extracellular Exosome
Condensed Chromosome
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Microtubule
Axonemal Microtubule
Cytoplasmic Microtubule
Plasma Membrane
Cilium
Microtubule Cytoskeleton
Motile Cilium
Neuromuscular Junction
Sperm Flagellum
Cytoplasmic Ribonucleoprotein Granule
Cell Projection
Synapse
Recycling Endosome
Extracellular Exosome
Molecular Function
Nucleotide Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Transferase Activity
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Nucleotide Binding
Structural Molecule Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Hydrolase Activity
Identical Protein Binding
Protein-containing Complex Binding
Metal Ion Binding
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Protein Polyubiquitination
DNA Repair
Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Apoptotic Process
DNA Damage Response
Protein Ubiquitination
Negative Regulation Of BMP Signaling Pathway
Protein Modification Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Autoubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Positive Regulation Of Protein Targeting To Mitochondrion
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Neuron Migration
Startle Response
Intracellular Protein Transport
Microtubule-based Process
Centrosome Cycle
Smoothened Signaling Pathway
Memory
Locomotory Behavior
Adult Locomotory Behavior
Visual Learning
Response To Mechanical Stimulus
Glial Cell Differentiation
Gene Expression
Dentate Gyrus Development
Cerebellar Cortex Morphogenesis
Hippocampus Development
Pyramidal Neuron Differentiation
Cerebral Cortex Development
Neurogenesis
Neuron Differentiation
Flagellated Sperm Motility
Adult Behavior
Cytoskeleton-dependent Intracellular Transport
Response To Tumor Necrosis Factor
Locomotory Exploration Behavior
Microtubule Polymerization
Forebrain Morphogenesis
Homeostasis Of Number Of Cells Within A Tissue
Regulation Of Synapse Organization
Synapse Organization
Cell Division
Neuron Apoptotic Process
Motor Behavior
Cellular Response To Calcium Ion
Organelle Transport Along Microtubule
Neuron Projection Arborization
Response To L-glutamate
Pathways
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
TICAM1, RIP1-mediated IKK complex recruitment
Signaling by BMP
Downregulation of SMAD2/3:SMAD4 transcriptional activity
PINK1-PRKN Mediated Mitophagy
Regulation of TNFR1 signaling
E3 ubiquitin ligases ubiquitinate target proteins
Neddylation
Peroxisomal protein import
Negative regulators of DDX58/IFIH1 signaling
IKK complex recruitment mediated by RIP1
Inactivation of CSF3 (G-CSF) signaling
Antigen processing: Ubiquitination & Proteasome degradation
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Post-chaperonin tubulin folding pathway
Recycling pathway of L1
Recycling pathway of L1
Hedgehog 'off' state
Anchoring of the basal body to the plasma membrane
Cargo trafficking to the periciliary membrane
Intraflagellar transport
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
Carboxyterminal post-translational modifications of tubulin
Carboxyterminal post-translational modifications of tubulin
HCMV Early Events
Assembly and cell surface presentation of NMDA receptors
Activation of AMPK downstream of NMDARs
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Sealing of the nuclear envelope (NE) by ESCRT-III
Kinesins
PKR-mediated signaling
Drugs
Albendazole
Vinblastine
Mebendazole
Epothilone D
Patupilone
CYT997
2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Artenimol
Phenethyl Isothiocyanate
Colchiceine
Diseases
Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS
Alanine aminotransferase levels (
33547301
)
Asthma and attention deficit hyperactivity disorder (
31619474
)
Diastolic blood pressure (
30224653
)
Shoulder impingement or rotator cuff tear (
33482370
)
Brain morphology (MOSTest) (
32665545
)
Composite immunoglobulin trait (IgG/IgM) (
28628107
)
Interacting Genes
223 interacting genes:
AMBRA1
AMFR
ANAPC11
AREL1
ARIH1
ARIH2
ARK2C
ATXN3
BARD1
BFAR
BIRC2
BIRC3
BIRC7
BIRC8
BMI1
BRCA1
CADPS2
CBL
CBLC
CHFR
CNOT4
CRBN
CSNK2A1
CUL2
CUL4B
DBN1
DCAF1
DCUN1D1
DTX1
DTX2
DTX3
DTX3L
DZIP3
EPS15
F12
FBXL12
FBXL2
FBXO2
FBXO25
FBXO4
FBXO7
FBXW10
FBXW11
FBXW8
FOCAD
FZR1
H2AC4
HDAC6
HECTD1
HECTD3
HECW1
HECW2
HERC1
HERC2
HSP90AB1
HSPA1A
IKBKG
ITCH
KAT2B
KDM1B
KLHL3
LRSAM1
MAEA
MAP3K1
MAPT
MARCHF3
MARCHF5
MARCHF7
MARCHF8
MDM2
MDM4
MEX3B
MEX3C
MGRN1
MIB1
MID1
MID2
MKRN1
MKRN3
MSL1
MSL2
MUL1
MYCBP2
MYLIP
NBR1
NEDD4
NEDD4L
NFKB1
NFKBIA
NHLRC1
NOSIP
OTUB1
PCGF1
PCGF2
PCGF3
PCGF5
PCGF6
PCNA
PDCD5
PELI1
PJA1
PJA2
POLL
POLM
PPP4C
PRPF19
RABGEF1
RBCK1
RBX1
RCHY1
RELA
RFFL
RFWD3
RIGI
RING1
RLIM
RMND5B
RNF103
RNF111
RNF113A
RNF114
RNF115
RNF122
RNF125
RNF126
RNF13
RNF130
RNF14
RNF150
RNF166
RNF167
RNF168
RNF181
RNF185
RNF19B
RNF2
RNF213
RNF216
RNF220
RNF26
RNF31
RNF34
RNF38
RNF4
RNF41
RNF43
RNF5
RNF8
RNFT1
RPLP1
RSPRY1
SAT1
SH3RF1
SIAH1
SIAH2
SMURF1
SMURF2
STAM2
STAU1
STK25
STUB1
SYVN1
TMEM129
TOPORS
TRAF6
TRAIP
TRIM10
TRIM13
TRIM17
TRIM2
TRIM21
TRIM23
TRIM25
TRIM26
TRIM27
TRIM28
TRIM3
TRIM31
TRIM32
TRIM33
TRIM35
TRIM37
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM54
TRIM55
TRIM58
TRIM62
TRIM63
TRIM68
TRIM69
TRIM7
TRIM8
TUBA1A
UBA1
UBA6
UBASH3B
UBC
UBE2O
UBE3A
UBE3C
UBE4A
UBE4B
UBOX5
UBR5
UFM1
UHRF1
USP7
UVSSA
VHL
WSB1
WWP1
WWP2
XIAP
XPNPEP1
ZNF598
ZNRF1
ZNRF2
ZNRF4
66 interacting genes:
ANXA7
ARL3
ATXN3
B4GALT1
BTG1
C8orf33
CDKN1A
CDKN2A
CEP20
CLIP1
CNP
CPEB2
CXCR1
CYLD
DAG1
DUSP23
EGFR
EIF4ENIF1
EML1
ENO1
GEMIN7
GRM7
GSK3B
GZMB
HTRA2
KEL
KPNB1
LINC01554
LRRK2
MAP7D3
MAPK6
MAPRE1
MAX
MX1
MYC
NFATC1
NUDT3
OGT
PAFAH1B1
PGK1
PLA2G7
PLK2
S100A8
S100A9
SDC3
SIAH1
SMN1
SNCA
SOCS6
SOCS7
SPART
STARD13
STK11
SYK
SYTL4
TAOK2
TIMM17A
TK1
TLN1
TTR
TUBB
UBE2D3
VAV1
VCL
YWHAQ
ZAP70
Entrez ID
7323
7846
HPRD ID
04269
03959
Ensembl ID
ENSG00000109332
ENSG00000167552
Uniprot IDs
D6RAH7
P61077
Q71U36
PDB IDs
1X23
2FUH
3L1Z
3RPG
3UGB
4BVU
4R8P
4S3O
5EGG
5IFR
6CP0
6T7F
7JZV
7LYB
8AMS
8GRQ
8SMW
8SMX
8SMY
8SMZ
8SN0
8SN1
8SN2
8SN3
8SN4
8SN5
8SN6
8SN7
8SN8
8SN9
8SNA
8U14
8UPF
8UQ8
8UQ9
8UQA
8UQB
8UQC
8UQD
8UQE
8X7I
8X7J
8X7K
9IPU
5JCO
6J8F
6WSL
7C1M
7UN1
7UNG
8J07
8SH7
Enriched GO Terms of Interacting Partners
?
Ubiquitin Protein Ligase Activity
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Post-translational Protein Modification
Ubiquitin-protein Transferase Activity
Protein Modification Process
Protein Polyubiquitination
Modification-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Transferase Activity
Protein Metabolic Process
Macromolecule Catabolic Process
Zinc Ion Binding
Proteolysis
Macromolecule Metabolic Process
Catabolic Process
Metal Ion Binding
Proteasomal Protein Catabolic Process
Protein Catabolic Process
Protein Autoubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Protein K63-linked Ubiquitination
Ubiquitin Ligase Complex
Cytoplasm
Response To Stress
Cellular Response To Stress
Protein Monoubiquitination
Regulation Of Signal Transduction
Ubiquitin-ubiquitin Ligase Activity
Regulation Of Signaling
Regulation Of Post-translational Protein Modification
Regulation Of Cell Communication
Ubiquitin Protein Ligase Binding
Positive Regulation Of Catabolic Process
Ubiquitin Binding
Cytosol
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Metabolic Process
Suppression Of Viral Release By Host
Innate Immune Response
Positive Regulation Of Post-translational Protein Modification
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Signal Transduction
DNA Damage Response
Positive Regulation Of Protein Ubiquitination
Regulation Of Protein Catabolic Process
Immune System Process
Negative Regulation Of Signaling
Cytoplasm
Cytosol
Regulation Of Cell Growth
Intracellular Signaling Cassette
Microtubule Binding
Regulation Of Growth
Microtubule Cytoskeleton Organization
Intracellular Signal Transduction
Regulation Of Cellular Component Organization
Organelle Organization
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Positive Regulation Of Programmed Cell Death
Protein-containing Complex
Regulation Of Signal Transduction
Positive Regulation Of Signal Transduction
Cytoskeleton
Positive Regulation Of Cell Communication
Regulation Of Cell Communication
Kinase Activity
Positive Regulation Of Signaling
Regulation Of Signaling
Protein Metabolic Process
Regulation Of Developmental Process
Regulation Of Intrinsic Apoptotic Signaling Pathway
Myeloid Leukocyte Migration
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Negative Regulation Of Signal Transduction
Cell Migration
Neutrophil Chemotaxis
Developmental Process
Cytoplasmic Microtubule
Microtubule-based Process
Ubiquitin Protein Ligase Binding
Catabolic Process
Leukocyte Migration
Protein Serine/threonine Kinase Activity
Protein Kinase Activity
Tubulin Binding
Negative Regulation Of Cell Growth
Cytoskeleton Organization
Neutrophil Migration
Protein Localization To Nucleus
Cellular Developmental Process
Microtubule Cytoskeleton
Microtubule
Positive Regulation Of Apoptotic Process
Leukocyte Aggregation
Regulation Of Microtubule-based Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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