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UBE2D3 and BIRC7
Number of citations of the paper that reports this interaction (PubMedID
21113135
)
45
Data Source:
BioGRID
(two hybrid)
UBE2D3
BIRC7
Description
ubiquitin conjugating enzyme E2 D3
baculoviral IAP repeat containing 7
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Endosome
Cytosol
Plasma Membrane
Endosome Membrane
Membrane
Extracellular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Centrosome
Cytosol
Molecular Function
Nucleotide Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Transferase Activity
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Ubiquitin-protein Transferase Activity
Cysteine-type Endopeptidase Inhibitor Activity
Protein Binding
Zinc Ion Binding
Transferase Activity
Enzyme Binding
Peptidase Inhibitor Activity
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Protein Polyubiquitination
DNA Repair
Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Apoptotic Process
DNA Damage Response
Protein Ubiquitination
Negative Regulation Of BMP Signaling Pathway
Protein Modification Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Autoubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Protein K6-linked Ubiquitination
Positive Regulation Of Protein Targeting To Mitochondrion
Lens Development In Camera-type Eye
Apoptotic Process
Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Protein Ubiquitination
Positive Regulation Of Protein Ubiquitination
Regulation Of Cell Population Proliferation
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Positive Regulation Of JNK Cascade
Regulation Of Cell Cycle
Regulation Of Natural Killer Cell Apoptotic Process
Pathways
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
TICAM1, RIP1-mediated IKK complex recruitment
Signaling by BMP
Downregulation of SMAD2/3:SMAD4 transcriptional activity
PINK1-PRKN Mediated Mitophagy
Regulation of TNFR1 signaling
E3 ubiquitin ligases ubiquitinate target proteins
Neddylation
Peroxisomal protein import
Negative regulators of DDX58/IFIH1 signaling
IKK complex recruitment mediated by RIP1
Inactivation of CSF3 (G-CSF) signaling
Antigen processing: Ubiquitination & Proteasome degradation
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Regulation of MITF-M-dependent genes involved in apoptosis
Drugs
Diseases
GWAS
Alanine aminotransferase levels (
33547301
)
Asthma and attention deficit hyperactivity disorder (
31619474
)
Diastolic blood pressure (
30224653
)
Shoulder impingement or rotator cuff tear (
33482370
)
Interacting Genes
223 interacting genes:
AMBRA1
AMFR
ANAPC11
AREL1
ARIH1
ARIH2
ARK2C
ATXN3
BARD1
BFAR
BIRC2
BIRC3
BIRC7
BIRC8
BMI1
BRCA1
CADPS2
CBL
CBLC
CHFR
CNOT4
CRBN
CSNK2A1
CUL2
CUL4B
DBN1
DCAF1
DCUN1D1
DTX1
DTX2
DTX3
DTX3L
DZIP3
EPS15
F12
FBXL12
FBXL2
FBXO2
FBXO25
FBXO4
FBXO7
FBXW10
FBXW11
FBXW8
FOCAD
FZR1
H2AC4
HDAC6
HECTD1
HECTD3
HECW1
HECW2
HERC1
HERC2
HSP90AB1
HSPA1A
IKBKG
ITCH
KAT2B
KDM1B
KLHL3
LRSAM1
MAEA
MAP3K1
MAPT
MARCHF3
MARCHF5
MARCHF7
MARCHF8
MDM2
MDM4
MEX3B
MEX3C
MGRN1
MIB1
MID1
MID2
MKRN1
MKRN3
MSL1
MSL2
MUL1
MYCBP2
MYLIP
NBR1
NEDD4
NEDD4L
NFKB1
NFKBIA
NHLRC1
NOSIP
OTUB1
PCGF1
PCGF2
PCGF3
PCGF5
PCGF6
PCNA
PDCD5
PELI1
PJA1
PJA2
POLL
POLM
PPP4C
PRPF19
RABGEF1
RBCK1
RBX1
RCHY1
RELA
RFFL
RFWD3
RIGI
RING1
RLIM
RMND5B
RNF103
RNF111
RNF113A
RNF114
RNF115
RNF122
RNF125
RNF126
RNF13
RNF130
RNF14
RNF150
RNF166
RNF167
RNF168
RNF181
RNF185
RNF19B
RNF2
RNF213
RNF216
RNF220
RNF26
RNF31
RNF34
RNF38
RNF4
RNF41
RNF43
RNF5
RNF8
RNFT1
RPLP1
RSPRY1
SAT1
SH3RF1
SIAH1
SIAH2
SMURF1
SMURF2
STAM2
STAU1
STK25
STUB1
SYVN1
TMEM129
TOPORS
TRAF6
TRAIP
TRIM10
TRIM13
TRIM17
TRIM2
TRIM21
TRIM23
TRIM25
TRIM26
TRIM27
TRIM28
TRIM3
TRIM31
TRIM32
TRIM33
TRIM35
TRIM37
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM54
TRIM55
TRIM58
TRIM62
TRIM63
TRIM68
TRIM69
TRIM7
TRIM8
TUBA1A
UBA1
UBA6
UBASH3B
UBC
UBE2O
UBE3A
UBE3C
UBE4A
UBE4B
UBOX5
UBR5
UFM1
UHRF1
USP7
UVSSA
VHL
WSB1
WWP1
WWP2
XIAP
XPNPEP1
ZNF598
ZNRF1
ZNRF2
ZNRF4
37 interacting genes:
AURKC
BOLA1
BOLA2
BOLA2B
CASP3
CASP7
CASP9
DDX6
DIABLO
FAM124B
GTF2A1
HTRA2
KANK2
LCOR
LMO4
NTAQ1
PHF1
POLR1C
PRR35
PSMB1
PTCD3
QARS1
SOX5
TEPSIN
TLE5
TNPO2
TSGA10IP
TTPA
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2I
UBE2K
USP2
VPS37C
XAF1
Entrez ID
7323
79444
HPRD ID
04269
05761
Ensembl ID
ENSG00000109332
ENSG00000101197
Uniprot IDs
D6RAH7
P61077
Q96CA5
PDB IDs
1X23
2FUH
3L1Z
3RPG
3UGB
4BVU
4R8P
4S3O
5EGG
5IFR
6CP0
6T7F
7JZV
7LYB
8AMS
8GRQ
8SMW
8SMX
8SMY
8SMZ
8SN0
8SN1
8SN2
8SN3
8SN4
8SN5
8SN6
8SN7
8SN8
8SN9
8SNA
8U14
8UPF
8UQ8
8UQ9
8UQA
8UQB
8UQC
8UQD
8UQE
8X7I
8X7J
8X7K
9IPU
1OXN
1OXQ
1OY7
1TW6
2I3H
2I3I
3F7G
3F7H
3F7I
3GT9
3GTA
3UW5
4AUQ
Enriched GO Terms of Interacting Partners
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Ubiquitin Protein Ligase Activity
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Post-translational Protein Modification
Ubiquitin-protein Transferase Activity
Protein Modification Process
Protein Polyubiquitination
Modification-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Transferase Activity
Protein Metabolic Process
Macromolecule Catabolic Process
Zinc Ion Binding
Proteolysis
Macromolecule Metabolic Process
Catabolic Process
Metal Ion Binding
Proteasomal Protein Catabolic Process
Protein Catabolic Process
Protein Autoubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Protein K63-linked Ubiquitination
Ubiquitin Ligase Complex
Cytoplasm
Response To Stress
Cellular Response To Stress
Protein Monoubiquitination
Regulation Of Signal Transduction
Ubiquitin-ubiquitin Ligase Activity
Regulation Of Signaling
Regulation Of Post-translational Protein Modification
Regulation Of Cell Communication
Ubiquitin Protein Ligase Binding
Positive Regulation Of Catabolic Process
Ubiquitin Binding
Cytosol
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Metabolic Process
Suppression Of Viral Release By Host
Innate Immune Response
Positive Regulation Of Post-translational Protein Modification
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Signal Transduction
DNA Damage Response
Positive Regulation Of Protein Ubiquitination
Regulation Of Protein Catabolic Process
Immune System Process
Negative Regulation Of Signaling
Ubiquitin Conjugating Enzyme Activity
Proteolysis
Protein Metabolic Process
Macromolecule Catabolic Process
Fibroblast Apoptotic Process
Iron-sulfur Cluster Assembly Complex
Modification-dependent Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Protein K48-linked Ubiquitination
Neuron Apoptotic Process
Nucleus
Cysteine-type Endopeptidase Activity
Proteolysis Involved In Protein Catabolic Process
Macromolecule Metabolic Process
Iron-sulfur Cluster Assembly
Execution Phase Of Apoptosis
Negative Regulation Of Macromolecule Biosynthetic Process
Cellular Response To Staurosporine
Cytosol
Negative Regulation Of Biosynthetic Process
Glial Cell Apoptotic Process
Protein Maturation
Post-translational Protein Modification
Response To Interferon-beta
Response To Anesthetic
Negative Regulation Of Metabolic Process
Cell Redox Homeostasis
Protein Binding
Negative Regulation Of Macromolecule Metabolic Process
Leukocyte Apoptotic Process
Negative Regulation Of Transcription By RNA Polymerase II
Cysteine-type Peptidase Activity
Response To Cobalt Ion
Ubiquitin-protein Transferase Activity
[2Fe-2S] Cluster Assembly
CD40 Receptor Complex
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Protein Polyubiquitination
Intracellular Iron Ion Homeostasis
Protein Modification Process
Positive Regulation Of Neuron Apoptotic Process
Catabolic Process
Apoptotic Process
Intrinsic Apoptotic Signaling Pathway
Histone Methyltransferase Binding
Negative Regulation Of RNA Metabolic Process
Protein Processing
Protein Poly-ADP-ribosylation
Programmed Cell Death
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Tagcloud (Difference)
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Tagcloud (Intersection)
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