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TUBA1A and MAPRE1
Number of citations of the paper that reports this interaction (PubMedID
16455083
)
22
Data Source:
BioGRID
(pull down)
TUBA1A
MAPRE1
Description
tubulin alpha 1a
microtubule associated protein RP/EB family member 1
Image
GO Annotations
Cellular Component
Condensed Chromosome
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Microtubule
Axonemal Microtubule
Cytoplasmic Microtubule
Plasma Membrane
Cilium
Microtubule Cytoskeleton
Motile Cilium
Neuromuscular Junction
Sperm Flagellum
Cytoplasmic Ribonucleoprotein Granule
Cell Projection
Synapse
Recycling Endosome
Extracellular Exosome
Spindle Pole
Cytoplasm
Golgi Apparatus
Centrosome
Microtubule Organizing Center
Spindle
Cytosol
Cytoskeleton
Microtubule
Cytoplasmic Microtubule
Focal Adhesion
Microtubule Cytoskeleton
Cortical Microtubule Cytoskeleton
Cell Projection Membrane
Microtubule Plus-end
Ciliary Basal Body
Cell Projection
Spindle Midzone
Mitotic Spindle Pole
Mitotic Spindle Astral Microtubule End
Mitotic Spindle Microtubule
Molecular Function
Nucleotide Binding
Structural Molecule Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Hydrolase Activity
Identical Protein Binding
Protein-containing Complex Binding
Metal Ion Binding
Protein Heterodimerization Activity
RNA Binding
Protein Binding
Microtubule Binding
Identical Protein Binding
Cadherin Binding
Microtubule Plus-end Binding
Protein Serine/threonine Kinase Binding
Biological Process
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Neuron Migration
Startle Response
Intracellular Protein Transport
Microtubule-based Process
Centrosome Cycle
Smoothened Signaling Pathway
Memory
Locomotory Behavior
Adult Locomotory Behavior
Visual Learning
Response To Mechanical Stimulus
Glial Cell Differentiation
Gene Expression
Dentate Gyrus Development
Cerebellar Cortex Morphogenesis
Hippocampus Development
Pyramidal Neuron Differentiation
Cerebral Cortex Development
Neurogenesis
Neuron Differentiation
Flagellated Sperm Motility
Adult Behavior
Cytoskeleton-dependent Intracellular Transport
Response To Tumor Necrosis Factor
Locomotory Exploration Behavior
Microtubule Polymerization
Forebrain Morphogenesis
Homeostasis Of Number Of Cells Within A Tissue
Regulation Of Synapse Organization
Synapse Organization
Cell Division
Neuron Apoptotic Process
Motor Behavior
Cellular Response To Calcium Ion
Organelle Transport Along Microtubule
Neuron Projection Arborization
Response To L-glutamate
Establishment Of Mitotic Spindle Orientation
Microtubule Bundle Formation
Intracellular Protein Localization
Cell Migration
Regulation Of Microtubule Polymerization Or Depolymerization
Negative Regulation Of Microtubule Polymerization
Positive Regulation Of Microtubule Polymerization
Protein Localization To Microtubule
Microtubule Polymerization
Spindle Assembly
Cell Division
Attachment Of Mitotic Spindle Microtubules To Kinetochore
Protein Localization To Centrosome
Protein Localization To Mitotic Spindle
Protein Localization To Astral Microtubule
Non-motile Cilium Assembly
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Post-chaperonin tubulin folding pathway
Recycling pathway of L1
Recycling pathway of L1
Hedgehog 'off' state
Anchoring of the basal body to the plasma membrane
Cargo trafficking to the periciliary membrane
Intraflagellar transport
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
Carboxyterminal post-translational modifications of tubulin
Carboxyterminal post-translational modifications of tubulin
HCMV Early Events
Assembly and cell surface presentation of NMDA receptors
Activation of AMPK downstream of NMDARs
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Sealing of the nuclear envelope (NE) by ESCRT-III
Kinesins
PKR-mediated signaling
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
RHO GTPases Activate Formins
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
EML4 and NUDC in mitotic spindle formation
Drugs
Albendazole
Vinblastine
Mebendazole
Epothilone D
Patupilone
CYT997
2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Artenimol
Phenethyl Isothiocyanate
Colchiceine
Diseases
Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS
Brain morphology (MOSTest) (
32665545
)
Composite immunoglobulin trait (IgG/IgM) (
28628107
)
Brain morphology (MOSTest) (
32665545
)
Mean platelet volume (
32888494
)
Oily fish consumption (
32066663
)
Polycystic ovary syndrome (
30566500
)
Pork consumption (
32066663
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Interacting Genes
66 interacting genes:
ANXA7
ARL3
ATXN3
B4GALT1
BTG1
C8orf33
CDKN1A
CDKN2A
CEP20
CLIP1
CNP
CPEB2
CXCR1
CYLD
DAG1
DUSP23
EGFR
EIF4ENIF1
EML1
ENO1
GEMIN7
GRM7
GSK3B
GZMB
HTRA2
KEL
KPNB1
LINC01554
LRRK2
MAP7D3
MAPK6
MAPRE1
MAX
MX1
MYC
NFATC1
NUDT3
OGT
PAFAH1B1
PGK1
PLA2G7
PLK2
S100A8
S100A9
SDC3
SIAH1
SMN1
SNCA
SOCS6
SOCS7
SPART
STARD13
STK11
SYK
SYTL4
TAOK2
TIMM17A
TK1
TLN1
TTR
TUBB
UBE2D3
VAV1
VCL
YWHAQ
ZAP70
50 interacting genes:
ABCB1
APC
APC2
APP
AURKB
BCL3
C20orf202
CASK
CCSER1
CDC42
CDK5RAP2
CLASP1
CLASP2
COPS5
COPS8
CSN3
CYLD
DCTN1
GTSE1
HSPA1A
IKBKG
KAT2B
KAT5
KLHL12
KLHL21
KNSTRN
LMO2
LRP1
MACF1
MARCHF7
MEOX2
NAV1
NUPR1
PAX6
PIK3R4
POLE2
PQBP1
PRPF3
PSMA1
SLAIN1
SPDYE2
SPDYE2B
SRC
SRPK2
STK11
TERF1
TRAF2
TUBA1A
TUBB
ZNF653
Entrez ID
7846
22919
HPRD ID
03959
04379
Ensembl ID
ENSG00000167552
ENSG00000101367
Uniprot IDs
Q71U36
Q15691
PDB IDs
5JCO
6J8F
6WSL
7C1M
7UN1
7UNG
8J07
8SH7
1PA7
1TXQ
1UEG
1VKA
1WU9
1YIB
1YIG
2HKQ
2HL3
2HL5
2QJZ
2R8U
3GJO
3MTU
3MUD
3TQ7
4XA1
4XA3
4XA6
5JV3
5JVM
5JVP
5JVR
5JVS
5JVU
5JX1
5WLQ
6PF2
6PFP
6YF5
6YSH
Enriched GO Terms of Interacting Partners
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Cytoplasm
Cytosol
Regulation Of Cell Growth
Intracellular Signaling Cassette
Microtubule Binding
Regulation Of Growth
Microtubule Cytoskeleton Organization
Intracellular Signal Transduction
Regulation Of Cellular Component Organization
Organelle Organization
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Positive Regulation Of Programmed Cell Death
Protein-containing Complex
Regulation Of Signal Transduction
Positive Regulation Of Signal Transduction
Cytoskeleton
Positive Regulation Of Cell Communication
Regulation Of Cell Communication
Kinase Activity
Positive Regulation Of Signaling
Regulation Of Signaling
Protein Metabolic Process
Regulation Of Developmental Process
Regulation Of Intrinsic Apoptotic Signaling Pathway
Myeloid Leukocyte Migration
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Negative Regulation Of Signal Transduction
Cell Migration
Neutrophil Chemotaxis
Developmental Process
Cytoplasmic Microtubule
Microtubule-based Process
Ubiquitin Protein Ligase Binding
Catabolic Process
Leukocyte Migration
Protein Serine/threonine Kinase Activity
Protein Kinase Activity
Tubulin Binding
Negative Regulation Of Cell Growth
Cytoskeleton Organization
Neutrophil Migration
Protein Localization To Nucleus
Cellular Developmental Process
Microtubule Cytoskeleton
Microtubule
Positive Regulation Of Apoptotic Process
Leukocyte Aggregation
Regulation Of Microtubule-based Process
Regulation Of Microtubule-based Process
Cytoskeleton
Regulation Of Microtubule Polymerization Or Depolymerization
Microtubule
Regulation Of Attachment Of Spindle Microtubules To Kinetochore
Regulation Of Microtubule Cytoskeleton Organization
Cytoplasmic Microtubule
Microtubule Cytoskeleton Organization
Regulation Of Cell Cycle
Microtubule-based Process
Establishment Of Mitotic Spindle Localization
Regulation Of Cellular Component Organization
Regulation Of Cytoskeleton Organization
Cytoplasm
Microtubule Cytoskeleton
Regulation Of Organelle Organization
Establishment Of Organelle Localization
Organelle Localization
Mitotic Spindle
Microtubule Plus-end
Positive Regulation Of Cellular Component Organization
Cytoskeleton Organization
Regulation Of Supramolecular Fiber Organization
Establishment Of Spindle Localization
Kinetochore
Spindle Localization
Centrosome
Positive Regulation Of Supramolecular Fiber Organization
Regulation Of Microtubule Polymerization
Positive Regulation Of Microtubule Polymerization
Microtubule Binding
Cellular Component Assembly
Regulation Of Microtubule Depolymerization
Microtubule Cytoskeleton Organization Involved In Mitosis
Cytosol
Establishment Of Localization In Cell
Establishment Of Spindle Orientation
Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Protein Metabolic Process
Microtubule Plus-end Binding
Spindle
Perinuclear Region Of Cytoplasm
Protein Kinase Binding
Negative Regulation Of Cellular Component Organization
Regulation Of Cell Cycle Process
Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of Cytoskeleton Organization
Regulation Of Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Attachment Of Mitotic Spindle Microtubules To Kinetochore
Positive Regulation Of Macromolecule Metabolic Process
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Tagcloud (Intersection)
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