TUBA1A and STARD13

Number of citations of the paper that reports this interaction (PMID 14697242)
13

Data Source:
BioGRID (two hybrid)

		TUBA1A	STARD13
Gene Name		tubulin, alpha 1a	StAR-related lipid transfer (START) domain containing 13
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Microtubule Cytoplasmic Microtubule Cytoplasmic Ribonucleoprotein Granule Recycling Endosome Extracellular Vesicular Exosome	Lipid Particle Cytosol Mitochondrial Membrane
	Molecular Function	GTPase Activity Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Protein Domain Specific Binding	GTPase Activator Activity Protein Binding Lipid Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Protein Folding Organelle Organization Microtubule-based Process Cytoskeleton-dependent Intracellular Transport Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Protein Polymerization Cell Division	Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Transport of connexons to the plasma membrane Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Hedgehog 'off' state Separation of Sister Chromatids Translocation of GLUT4 to the plasma membrane L1CAM interactions G2/M Transition Mitotic Anaphase Recycling pathway of L1 Recruitment of NuMA to mitotic centrosomes Regulation of PLK1 Activity at G2/M Transition Formation of tubulin folding intermediates by CCT/TriC Intraflagellar transport M Phase Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Post-chaperonin tubulin folding pathway Loss of Nlp from mitotic centrosomes Gap junction trafficking and regulation MHC class II antigen presentation Recruitment of mitotic centrosome proteins and complexes Protein folding Gap junction assembly Gap junction trafficking Kinesins Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Resolution of Sister Chromatid Cohesion Chaperonin-mediated protein folding Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Adaptive Immune System	Rho GTPase cycle Signaling by Rho GTPases
Drugs		Albendazole Vinblastine Mebendazole Epothilone D Epothilone B 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE
Diseases
GWAS			Body mass index (asthmatics) ( 23517042) Intracranial aneurysm ( 20364137)
Protein-Protein Interactions		53 interactors: ANXA7 ARL3 ATXN3 B4GALT1 BTG1 C8orf33 CDKN1A CDKN2A CLIP1 CNP CXCR1 CYLD DAG1 DUSP23 EGFR GEMIN7 GRM7 GSK3B GZMB HTRA2 KEL KPNB1 LRRK2 MAP2 MAPK6 MAPRE1 MAX MYC NFATC1 NUDT3 PAFAH1B1 PFDN1 PLA2G7 SDC3 SIAH1 SMN1 SNCA SOCS6 SOCS7 SPG20 STARD13 SYK TAOK2 TIMM17A TK1 TLN1 TTR TUBB UBE2D3 VAV1 VCL YWHAQ ZAP70	12 interactors: BAI2 EPB41L1 HMGCR HSP90AA1 HSP90AB1 ITPR1 KIF1B SMAD1 SMARCD3 TAX1BP1 TUBA1A TUBA4A
Entrez ID		7846	90627
HPRD ID		03959	11607
Ensembl ID		ENSG00000167552	ENSG00000133121
Uniprot IDs		Q71U36	B2R789 B3KRK6 Q9Y3M8
PDB IDs			2H80 2JW2 2PSO
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cell Communication Cell Death Death Intracellular Signal Transduction Signaling Programmed Cell Death Response To Stimulus Response To Organic Substance Positive Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Response To Stress Regulation Of Cellular Component Organization Negative Regulation Of Phosphorylation Apoptotic Process Developmental Process Cell Cycle Regulation Of Intracellular Transport System Development Regulation Of Intracellular Signal Transduction Defense Response Regulation Of Signal Transduction Regulation Of Signaling Cellular Response To Organic Substance Cellular Process Negative Regulation Of Intracellular Signal Transduction Locomotion Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Phosphorus Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Immune System Process Anatomical Structure Development Signal Transduction Regulation Of Phosphorylation Regulation Of Cell Death Immune Response-regulating Signaling Pathway Neuron Development Regulation Of Growth Nervous System Development Cell Differentiation Cell Development Regulation Of Kinase Activity Neuron Projection Morphogenesis Regulation Of Cellular Process Multicellular Organismal Development Innate Immune Response Cell Projection Morphogenesis Cell Migration	Cellular Response To Interleukin-4 Response To Interleukin-4 Protein Folding Cellular Protein Complex Assembly G2/M Transition Of Mitotic Cell Cycle Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Response To Organic Substance Protein Complex Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Muscle Cell Apoptotic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Cellular Macromolecular Complex Assembly Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Mitotic Cell Cycle Phase Transition Phagocytosis Cell Cycle Phase Transition Regulation Of Muscle Cell Apoptotic Process Fc Receptor Signaling Pathway Defense Response Immune Response-activating Cell Surface Receptor Signaling Pathway 'de Novo' Posttranslational Protein Folding Regulation Of Nitric Oxide Biosynthetic Process 'de Novo' Protein Folding Vesicle-mediated Transport Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Heat Innate Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Cell Death Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein Polymerization Immune Response-regulating Signaling Pathway Cellular Response To Organic Substance Response To Heat Cellular Component Assembly Response To Abiotic Stimulus Voluntary Musculoskeletal Movement Cardiac Right Ventricle Formation Protein Import Into Mitochondrial Outer Membrane Establishment Of Localization In Cell Response To Unfolded Protein Cytoskeleton-dependent Intracellular Transport Regulation Of Protein Binding Cellular Response To Cytokine Stimulus Regulation Of Reactive Oxygen Species Metabolic Process
Tagcloud ?		brainstem calorimetry elucidate exerts feeding fret interactive interacts isothermal itc library neurodegeneration neurological screened se sec selenium selenocysteines selenoprotein selenoproteins selp terminus titration trace transporter tubulin verified widespread	aberrant abilities addressed appearing bioinformatics certified clinicopathological colony colorectal corresponding crc curve distant healing indicator invasion kaplan luciferase lymphatic meier metastasis mimics mir nats poorer tnm untranslated utr wound
Tagcloud (Difference) ?		brainstem calorimetry elucidate exerts feeding fret interactive interacts isothermal itc library neurodegeneration neurological screened se sec selenium selenocysteines selenoprotein selenoproteins selp terminus titration trace transporter tubulin verified widespread	aberrant abilities addressed appearing bioinformatics certified clinicopathological colony colorectal corresponding crc curve distant healing indicator invasion kaplan luciferase lymphatic meier metastasis mimics mir nats poorer tnm untranslated utr wound
Tagcloud (Intersection) ?