TUBA1A and STARD13

Number of citations of the paper that reports this interaction (PubMedID 14697242)
0

Data Source:
BioGRID (two hybrid)

		TUBA1A	STARD13
Description		tubulin alpha 1a	StAR related lipid transfer domain containing 13
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GO Annotations	Cellular Component	Condensed Chromosome Nucleus Cytoplasm Cytosol Cytoskeleton Microtubule Axonemal Microtubule Cytoplasmic Microtubule Plasma Membrane Cilium Microtubule Cytoskeleton Motile Cilium Neuromuscular Junction Sperm Flagellum Cytoplasmic Ribonucleoprotein Granule Cell Projection Synapse Recycling Endosome Extracellular Exosome	Cytoplasm Mitochondrion Lipid Droplet Cytosol Membrane Mitochondrial Membrane
	Molecular Function	Nucleotide Binding Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Hydrolase Activity Identical Protein Binding Protein-containing Complex Binding Metal Ion Binding Protein Heterodimerization Activity	GTPase Activator Activity Protein Binding Lipid Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Neuron Migration Startle Response Intracellular Protein Transport Microtubule-based Process Centrosome Cycle Smoothened Signaling Pathway Memory Locomotory Behavior Adult Locomotory Behavior Visual Learning Response To Mechanical Stimulus Glial Cell Differentiation Gene Expression Dentate Gyrus Development Cerebellar Cortex Morphogenesis Hippocampus Development Pyramidal Neuron Differentiation Cerebral Cortex Development Neurogenesis Neuron Differentiation Flagellated Sperm Motility Adult Behavior Cytoskeleton-dependent Intracellular Transport Response To Tumor Necrosis Factor Locomotory Exploration Behavior Microtubule Polymerization Forebrain Morphogenesis Homeostasis Of Number Of Cells Within A Tissue Regulation Of Synapse Organization Synapse Organization Cell Division Neuron Apoptotic Process Motor Behavior Cellular Response To Calcium Ion Organelle Transport Along Microtubule Neuron Projection Arborization Response To L-glutamate	Signal Transduction Actin Cytoskeleton Organization Negative Regulation Of Cell Migration Regulation Of Rho Protein Signal Transduction Endothelial Cell Migration Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Endothelial Tube Lumen Extension Negative Regulation Of Sprouting Angiogenesis
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Regulation of PLK1 Activity at G2/M Transition HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Anchoring of the basal body to the plasma membrane Cargo trafficking to the periciliary membrane Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint AURKA Activation by TPX2 Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins PKR-mediated signaling	RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle
Drugs		Albendazole Vinblastine Mebendazole Epothilone D Patupilone CYT997 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE Artenimol Phenethyl Isothiocyanate Colchiceine
Diseases		Lissencephaly (LIS); Miller-Dieker syndrome (MDLS)
GWAS		Brain morphology (MOSTest) ( 32665545) Composite immunoglobulin trait (IgG/IgM) ( 28628107)	Body mass index in asthmatics ( 23517042) Colorectal cancer or advanced adenoma ( 30510241) Diverticular disease ( 30177863) Hematocrit ( 32888494) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Intracranial aneurysm ( 20364137) Metamizole-induced agranulocytosis or neutropenia ( 33138277) Mild age-related type 2 diabetes ( 34737425) Plasma amyloid beta peptide concentrations (ABx-40) ( 24535457) Platelet count ( 32888494) Plateletcrit ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		66 interacting genes: ANXA7 ARL3 ATXN3 B4GALT1 BTG1 C8orf33 CDKN1A CDKN2A CEP20 CLIP1 CNP CPEB2 CXCR1 CYLD DAG1 DUSP23 EGFR EIF4ENIF1 EML1 ENO1 GEMIN7 GRM7 GSK3B GZMB HTRA2 KEL KPNB1 LINC01554 LRRK2 MAP7D3 MAPK6 MAPRE1 MAX MX1 MYC NFATC1 NUDT3 OGT PAFAH1B1 PGK1 PLA2G7 PLK2 S100A8 S100A9 SDC3 SIAH1 SMN1 SNCA SOCS6 SOCS7 SPART STARD13 STK11 SYK SYTL4 TAOK2 TIMM17A TK1 TLN1 TTR TUBB UBE2D3 VAV1 VCL YWHAQ ZAP70	12 interacting genes: ADGRB2 EPB41L1 HMGCR HSP90AA1 HSP90AB1 ITPR1 KIF1B SMAD1 SMARCD3 TAX1BP1 TUBA1A TUBA4A
Entrez ID		7846	90627
HPRD ID		03959	11607
Ensembl ID		ENSG00000167552	ENSG00000133121
Uniprot IDs		Q71U36	B2R789 B3KRK6 H3BRG5 Q9Y3M8
PDB IDs		5JCO 6J8F 6WSL 7C1M 7UN1 7UNG 8J07 8SH7	2H80 2JW2 2PSO
Enriched GO Terms of Interacting Partners?		Cytoplasm Cytosol Regulation Of Cell Growth Intracellular Signaling Cassette Microtubule Binding Regulation Of Growth Microtubule Cytoskeleton Organization Intracellular Signal Transduction Regulation Of Cellular Component Organization Organelle Organization Negative Regulation Of Cell Communication Negative Regulation Of Signaling Positive Regulation Of Programmed Cell Death Protein-containing Complex Regulation Of Signal Transduction Positive Regulation Of Signal Transduction Cytoskeleton Positive Regulation Of Cell Communication Regulation Of Cell Communication Kinase Activity Positive Regulation Of Signaling Regulation Of Signaling Protein Metabolic Process Regulation Of Developmental Process Regulation Of Intrinsic Apoptotic Signaling Pathway Myeloid Leukocyte Migration Regulation Of Intracellular Signal Transduction Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Signal Transduction Cell Migration Neutrophil Chemotaxis Developmental Process Cytoplasmic Microtubule Microtubule-based Process Ubiquitin Protein Ligase Binding Catabolic Process Leukocyte Migration Protein Serine/threonine Kinase Activity Protein Kinase Activity Tubulin Binding Negative Regulation Of Cell Growth Cytoskeleton Organization Neutrophil Migration Protein Localization To Nucleus Cellular Developmental Process Microtubule Cytoskeleton Microtubule Positive Regulation Of Apoptotic Process Leukocyte Aggregation Regulation Of Microtubule-based Process	Nitric-oxide Synthase Regulator Activity Dendritic Growth Cone TPR Domain Binding Telomerase Holoenzyme Complex Assembly Axonal Growth Cone Chaperone-mediated Protein Complex Assembly RNA-templated DNA Biosynthetic Process MHC Class II Protein Complex Binding Telomere Maintenance Via Telomerase Disordered Domain Specific Binding DNA Polymerase Binding Telomere Maintenance Via Telomere Lengthening Apoptotic Process Protein Folding Chaperone Complex Cell Death Programmed Cell Death ATP-dependent Protein Folding Chaperone Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process Tau Protein Binding Visual Learning Hydroxymethylglutaryl-CoA Reductase (NADPH) Activity Nucleotide Binding CTP Binding DATP Binding Cellular Response To Heat Inositol 1,4,5-trisphosphate Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Levels Nuclear Inner Membrane Protein Folding Chaperone Regulation Of Nitric Oxide Biosynthetic Process Visual Behavior Regulation Of Nitric Oxide Metabolic Process Ubiquitin Protein Ligase Binding Neurofibrillary Tangle Assembly UTP Binding Sulfonylurea Receptor Binding HSP90-CDC37 Chaperone Complex Homomeric SMAD Protein Complex Protein Localization To Phagocytic Vesicle Protein-containing Complex Response To Unfolded Protein Response To Heat Microtubule Organelle Transport Along Microtubule Regulation Of Protein Catabolic Process Associative Learning DNA Biosynthetic Process Rho GDP-dissociation Inhibitor Binding GTP Binding ATP Hydrolysis Activity
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